The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO.sub.2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO.sub.2-to-NO reactor cartridge and/or a breakthrough of NO.sub.2, and providing an indication of the remaining useful life and/or breakthrough.

A flow of gases in a respiratory therapy system can be conditioned to achieve more consistent output from sensors configured to sense a characteristic of the flow. The flow can be mixed by imparting a tangential, rotary, helical, or swirling motion to the flow of gases. The mixing can occur upstream of the sensors. The flow can be segregated into smaller compartments to reduce turbulence in a region of the sensors.

A therapeutic gas source and cart and methods thereof for use with a therapeutic gas delivery system is disclosed. The therapeutic gas source may include a cylinder operable to contain a therapeutic gas that includes a body and a gas source valve body. In some examples, the gas source valve body has a valve and a coupling member.

A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.

A delivery device for and a method of delivering gases to the nasal airway, in particular therapeutic gases and gases in combination with active substances, either as powders or liquids, for enhanced uptake of the active substances.

A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.

The present invention pertains to a system, method, and device for treating sleep disorders. The present invention is particularly useful in the delivery of carbon dioxide (CO2) to a subject and in the treatment of sleep apnea. Furthermore, integration of components with various sensors and apparatuses associated therewith and attached thereto preferably complete a rebreathing circuit in the present invention. In various embodiments of the present invention where the above components are integrated as a rebreathing circuit, a subject is both the source and recipient of a controlled concentration of carbon dioxide. In such embodiments, treatment of sleep disorders becomes much more efficient and effective.

In one embodiment, the present invention provides a system to deliver at least one therapeutic gas to a spontaneously breathing patient, wherein the rate of delivery of the at least one therapeutic gas exceeds the patient's inspiratory flow rate, and the amount of the at least one therapeutic gas that is wasted is minimized or eliminated.

A motorised respiratory assistance device with an integrated cooling system including an enclosure (1) forming a compartment (2) accommodating a motor unit (3) driving turbines (8a, 8b) generating a main respiratory assistance air flow (F1) and a secondary air flow (F2) for cooling the motor (5). The secondary air flow (F2) is conveyed by a secondary aeraulic path (E2, E4, E5, 22, E3, S2) that includes an inner portion (E2, E4, E5, 22) extending into the motor (5) between the stator (6a) and the rotor (6b) and an outer portion (E3, S2) that extends into an annular space (E3) provided around the motor unit (3). The cooling air flow (F2) flows in opposing directions in the inner (E4) and outer (E3) portions, and the main aeraulic path (E1, E6, S1) and the secondary aeraulic path (E2, E4, E5, 22, E3, S2) are separated from each other by a partition (18).

An anesthetic gas delivery system includes a gas machine for supplying anesthetic gas to a patient; a scavenging control system that controls a level of vacuum suction to evacuate waste anesthetic gas; and a user interface electronically coupled to the scavenging control system. The scavenging control system includes an air flow sensor external from the gas machine that measures the flow rate of the waste anesthetic gas through the scavenging control system; a control valve, such as a proportional solenoid valve, that is controllable to adjust the level of vacuum suction to adjust the flow rate of the waste anesthetic gas; and electronic control circuitry that is configured to receive a measured flow rate from the sensor and to control the control valve to adjust the level of vacuum suction based on the flow rate measured by the sensor. The electronic control circuitry further is configured to transmit flow rate information corresponding to the flow rate measured by the sensor to the user interface.