A sedation device has a housing divided internally into a ventilator chamber and an associated evaporator chamber which overlap and are separated by a filter mounted between the chambers and forming a common gas-permeable dividing wall between the chambers. An inlet port is provided at one end of the ventilator chamber at a top of the housing for connection to a patient ventilator in use. An outlet port on the evaporator chamber can be connected via a breathing tube to a patient. An evaporator is mounted within the evaporator chamber for delivery of a volatile sedative into the evaporator chamber during use.

An infectious aerosol capture mask (IACM) includes a face tent coupled to a suction tube adapter. The face tent includes a proximal opening configured to be disposed over the mouth and nose of a patient. The face tent further includes a distal opening with a smaller diameter than the proximal opening. A coupler is configured to secure the suction tube adapter to the distal opening of the face tent. The suction tube adapter includes a suction port configured to be coupled to a suction tube for active capture of infectious aerosol and left unconnected for passive capture of infectious aerosol. A viral filter is disposed between the suction port and the face tent to capture infectious aerosols expelled by the patient. The IACM further includes one or more one-way valves that are configured to permit airflow into the face tent.

The present invention provides a system, a kit and a use thereof for oral mucosa delivery of a composition. The composition may comprise at least two sub-compositions admixed right before dispensing to the oral mucosa. In one embodiment, the system is a pressurized system. In another embodiment, the admixed sub-compositions are atomized. In one embodiment, one of the sub-compositions comprise a beneficiary gas, such as oxygen. In another embodiment, one of the sub-compositions comprise a nutritional supplement, a nutraceutical composition, a pharmaceutical composition, or any combinations thereof.

A reusable, elastomeric respirator and ventilator, with filter inserts, including a mask body having a pliant facial interface on the interior of the mask body, and two apertures centrally positioned on the front face of the mask body. Two interchangeable plugs or ports are provided to be received within and seal the apertures, deliver oxygen into the mask, or deliver liquids to a wearer of the mask. On opposing sides of the mask body are air filter housings which support an air filter, each air filter housing including a base support structure affixed to the mask body and a top securing structure removably secured to the base support structure. One or more straps are affixed to the mask body to secure the mask body about a wearer's head.

An adaptor for a respiratory assistance system delivers aerosols to a patient. The adaptor is lightweight with a small footprint to increase patient comfort. The adaptor has a nozzle and a sealing mechanism to maintain pressure therein regardless of whether the nozzle is inserted into the adaptor. The adaptor is configured to connect to medical tubing and a medicament delivery device.

A medical double configurational and multiple ports mask preferably including a multifunctional plug with or without a nebulizer oxygen delivery adaptor (“NODA”) attachment. The mask fits over the mouth and the nose and preferably contains at least two possible nose/face configurational solutions. The mask can be secured over the head with a stretchable or non-stretchable material. The position of the preferred triple ports of the double configurational mask provides improved structural construction reflecting different patient's nose/face features and allows for different types of procedures to be performed at the same time regardless of the patient's head/neck position. The multifunctional plug can be used for a variety of applications. The mask can be used with existing standardized disposable respiratory care equipment, including a simplified improved nebulizer oxygen adaptor (“SINODA”) and/or multifunctional use nebulizer oxygen delivery adaptor (“MUNODA”) attachment.

A personal respiratory isolation system (PRIS) provides a personal, negative pressure environment for a patient or user that reduces contamination and spread of pathogens exhaled by the patient into the environment. The PRIS includes an enclosure to receive the patient's head (such as a hood and a drape) and a negative pressure source which draws ambient air into the interior of the enclosure and draws air within the enclosure's interior (including the exhalations of the patient, including any contaminants and/or pathogens) out of the enclosure via a fluid port into a container for biohazard processing or disposal. The PRIS may allow positive air pressure therapeutic treatments to be delivered to the patient within the negative pressure environment, and the PRIS may maintain a constant pressure within the interior of the enclosure. The PRIS may include a transparent, hinged face shield for ease of patient observation and/or access.

Methods and devices to capture and analyze aerosolized particles such as protein biomarkers and their truncated proteoforms characteristic of a disease, including a respiratory disease, in exhaled breath to enable rapid detection of diseases are disclosed. The disclosed methods and systems selectively capture aerosolized particles using a packed bed column. The captured particles are then eluted using one or more solvents and analyzed using devices including mass spectrometry.

A nebulizer device aerosolizes (or vaporizes) liquid drawn from a liquid reservoir via a fluid flow path into a nebulization chamber. An inlet port is coupled to an external air supply and leads through a check valve and Venturi nozzle (e.g. a duckbill valve) into the chamber to direct an air stream across an opening of the fluid flow path. A discharge port leads from the chamber to a user mask, mouthpiece or canula, where the aerosol or vapor mixture can be inhaled. A filtered outlet port isolates exhaled material from the external environment. Multiple discrete heating elements may be placed around the fluid flow path to preheat the liquid. If the liquid is sufficiently volatile, heating may vaporize the material which can condense back into an aerosol after mixing with the air stream. A set of check valves direct one-way fluid flow and prevent leakage or spillage of material from the device.

Present invention is related to a ventilator adapter and auxiliary chamber thereof. The ventilator adapter of the present invention comprises a T-shaped flow guiding adapter and an auxiliary chamber detachably connected thereto. The T-shaped flow guiding adapter contains a guiding valve that can retractably close or open its opening. The auxiliary chamber is a cylindrical hollow tubing with open ends at both sides, and a chamber partition extended into the interior of the auxiliary chamber, separating the chamber at least partially into two chambers. The present invention is able to be adapted with the conventional ventilator pipeline by using the T-shaped flow guiding adapter for connecting any suitable ventilatory medicine with the auxiliary cavity. When the ventilatory medicine is administrated, the present invention is able to guide the gas flow within the ventilator pipeline reaching into the space of the auxiliary cavity and carrying the ventilatory medicine toward the patient successfully with high amount of medicine doses for better treatment result.