A catheter assembly may include a catheter, a catheter hub coupled to the catheter, an injection port on the catheter hub, and an injection port backflow control device. The backflow control device may include a concentric port, a bellow, and a duckbill valve. The injection port backflow control device may include a split septum and a duckbill valve. The injection port backflow control device may include a deformable annular valve disposed around an inner surface of the catheter hub and may block an opening in the catheter hub connected to the injection port. The injection port may receive a needleless syringe for administration of medicine or other fluids. The injection port backflow control device may permit fluids to flow into the catheter hub and may prevent fluids from flowing out of the catheter hub through the injection port.

In some embodiments, a device may include an intraventricular access device and an infusion device. The intraventricular access device may include more than one catheter and a container. In some embodiments, the catheter may include an aspiration lumen and an infusion lumen. A distal end of the intraventricular portion of the catheter may be positionable, during use, in a subject's brain fluid. In some embodiments, the container may be coupled to a proximal end of the aspiration lumen. The proximal end of the aspiration lumen may be in fluid communication with the container. In some embodiments, the container may include a barrier positioned between a proximal opening of the aspiration lumen and at least a portion of the infusion lumen adjacent to and/or associated with the container. The barrier may inhibit penetration of a surgical instrument.

The present invention relates to an extensible drug injection device capable of injecting a drug from a location away from a patient, and an operation method therefor. Disclosed is a drug injection device comprising: a first sub-line of which one end joins with a main line, connected from a first drug storage part for storing a first drug to be injected into a patient to the body of the patient such that the first drug flows therein, and of which the other end is extended to the other side; a second drug injection part which is connected to the first sub-line and which injects a second drug that is different from the first drug; and a second drug pumping part which is connected to the first sub-line, and which pushes, to the main line, the second drug having been injected by the second drug injection part into the first sub-line.

In some embodiments, a device may include an intraventricular access device and an infusion device. The intraventricular access device may include more than one catheter and a container. In some embodiments, the catheter may include an aspiration lumen and an infusion lumen. A distal end of the intraventricular portion of the catheter may be positionable, during use, in a subject's brain fluid. In some embodiments, the container may be coupled to a proximal end of the aspiration lumen. The proximal end of the aspiration lumen may be in fluid communication with the container. The proximal end of the infusion lumen may be in communication with an infusion pump. In some embodiments, the device inhibits cross contamination between a first fluid in the aspiration lumen and a second fluid in the infusion lumen. In some embodiments, the container may include a barrier positioned between a proximal opening of the aspiration lumen and at least a portion of the infusion lumen adjacent to and/or associated with the container. The barrier may inhibit penetration of a surgical instrument.

An ambulatory infusing device including a housing, a reservoir defining an interior volume, a wall associated with the housing and having an inner surface that faces into the reservoir interior volume, and a filter assembly. The filter assembly may include a filter assembly housing with a housing filter portion having a free end associated with the inner surface of the wall and a filter supporting volume that extends to the free end of the housing filter portion, and a filter located within the filter supporting volume that extends to at least the free end of the housing filter portion.

An infusion pump (100) includes a plunger (110) configured to squeeze a section of an infusion tube (150). A proximal valve (120), proximal to the plunger, ascends to allow infusion fluid intake from a reservoir to the infusion tube and descends to inhibit infusion fluid intake from the reservoir to the infusion tube. A distal valve (125), distal to the plunger, ascends to allow infusion fluid flow past the distal valve, and descends to inhibit infusion fluid flow past the distal valve. A controller (141) controls the plunger, proximal valve, and distal valve by initiating descending of the plunger concurrently with or prior to the ascending of the distal valve, such that the descending of the plunger compensates for suction produced by the ascending of the distal valve, thereby reducing backflow of fluid from the subject. Other applications are also described.

A safe and easy handling of a chemical-liquid circuit having various components. The opening/closing unit drive mechanism includes an opening/closing unit holder which detachably holds an opening/closing unit which includes a housing having flow channels and a piston for opening and closing the flow channels which is movably provided to the housing, a hook to be engaged with the piston of the opening/closing unit, which is disposed leaving a space from the opening/closing unit holder, and a linear motion mechanism which moves the hook back and forth. The opening/closing unit holder is movably supported between a first position at which the piston is engaged with the hook and a second position at which the piston is not engaged with the hook.

An ambulatory infusing device including a housing, a reservoir defining an interior volume, a wall associated with the housing and having an inner surface that faces into the reservoir interior volume, and a filter assembly. The filter assembly may include a filter assembly housing with a housing filter portion having a filter supporting volume, a filter located within the filter supporting volume, and a bubble guard, including a bubble guard wall and at least one bubble guard aperture that extends through the bubble guard wall, associated with the filter assembly housing such that the bubble guard wall is located in spaced relation to the filter.

A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient or user is provided. A soft needle or cannula can be placed in fluid communication with the liquid drug and can be coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the container to the patient through the soft needle or cannula. The wearable drug delivery device can include components for preventing backflow and eliminating air within the liquid drug. As a result, the comfort of the patient can be enhanced and correct drug dosages can be provided when using the drug delivery device.

A high crack pressure valve is described. The high crack pressure valve includes an inlet adapted to receive a medical fluid pressurized by a pump; an outlet in fluid communication with a fluid path element, wherein the fluid path element is in fluid communication with downstream system components of a fluid delivery system; and a moveable element having a crack pressure threshold. The moveable element has a first closed position and a second open position and is configured to move from the first closed position to the second open position when a fluid pressure at the inlet is greater than or equal to the crack pressure threshold. The pressure of fluid at the outlet of the high crack pressure valve has little or no effect on movement of the moveable element from the first closed position to the second open position. Fluid injector systems and fluid path elements which include the high crack pressure valve are also described.