According to one example of the present disclosure an infusion device is configured to control a medication delivery apparatus to intravenously deliver a pharmaceutical preparation to a patient. The infusion device comprises a processor and a memory storing instructions executable by the processor to cause the medication delivery apparatus to deliver the pharmaceutical preparation to the patient according to a predetermined dose profile. The predetermined dose profile is designed to deliver a therapeutic dose of the pharmaceutical preparation to the patient over a predetermined infusion time in a manner which facilitates safe detection of an adverse reaction of the patient to the pharmaceutical preparation, or desensitization the patient to the pharmaceutical preparation, during a first stage of administering the therapeutic dose.

A medical device with safety verification, comprising: a remote device; a functional device, the functional device can receive functional instructions from the remote device (100), the functional instructions include drug infusion instructions or non-infusion instructions; and a safety verification module installed in the functional device. After the safety verification module receives a verification instruction that matches the functional instruction, the functional device can execute the functional instruction; and the verification instruction includes the user's body movement. Before the medical device performs various functions, safety verification is required in order to improve the safety of the medical device.

An apparatus including a controller can determine a rate of change of a blood glucose level of a subject from blood glucose data and determine if there is a risk of the blood glucose level going high or low.

The present disclosure provides a new and innovative method and system for flow rate compensation in devices, such as infusion pumps. In various embodiments, a computer-implemented method includes determining a location of a plurality of infusion pumps in a pump stack including the plurality of infusion pumps and a fluid supply connected to each of the plurality of infusion pumps. The computer-implemented method also includes determining a reference infusion pump, in the plurality of infusion pumps, and adjusting the flow rate for each infusion pump in the plurality of infusion pumps based on the distance between the infusion pump and the reference infusion pump.

A surgical fluid management system includes a console and a cassette for delivering fluids to a surgical site. The console has a pump rotor and a pressure-sensing membrane. The cassette has a cassette housing, a flexible fluid delivery tube in the housing. The flexible fluid delivery tube has a lumen configured to interface with the pump rotor and to deliver a flow of fluid from a fluid source as the rotor is rotated. A pressure-transmitting membrane is located in a wall of the cassette housing and in fluid communication with said fluid delivery lumen. The pressure-transmitting membrane flexes outwardly in response to a positive pressure in the lumen and flexes inwardly in response to a negative pressure in the lumen. The pressure-transmitting membrane detachably adheres to or presses against the pressure-sensing membrane to cause the pressure-sensing membrane to move in response to pressure changes in the flexible fluid delivery tube.

A medical device is disclosed, which includes: an operation reception unit; a position acquisition unit capable of acquiring position information of a detection target that is in contact with or proximity to the operation reception unit, the position information being based on a position on the operation reception unit; and a control unit that identifies an operation input by the detection target based on a change in the acquired position information.

System and methods are provided for control of a therapeutic delivery system. A monitoring device includes a sensor for measuring a biometric parameter of a patient. A feature extractor generates a set of features for the patient, each of the set of features being associated with one of the patient and the therapeutic delivery system. A predictive model predicts a future value for the biometric parameter at a given time according to the set of features. A therapeutic delivery system controller determines a desired dosage for the therapeutic according to the predicted future value for the patient parameter.

Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device involves obtaining one or more measurement values of a physiological condition in the body of a user during an initial monitoring period and determining a fasting reference value for a metric based on the one or more measurement values. After the initial monitoring period, the method continues by obtaining an updated measurement value during a fasting period, determining a current value for the metric based at least in part on the updated measurement value, and generating a notification in response to a deviation between the current value and the fasting reference value exceeding a threshold indicative of insertion site loss or other loss of effectiveness.

Blood glucose control systems are disclosed. A blood glucose control system can receive a glucose level signal from a glucose sensor operatively coupled to a subject. The system can decode encoded data of the glucose level signal to obtain the glucose level of the subject and the indication of the glucose trend. The system can automatically calculate the dose control signal using a control algorithm configured to calculate regular correction boluses of glucose control agent in response to at least the glucose level of the subject. The system can select a dose control signal encoding profile from a plurality of dose control signal encoding profiles and, based on the dose control signal encoding profile, encode the dose control signal such that the pump controller can read the dose control signal. The system can transmit an encoded dose control signal to the pump controller.

Methods for programming an implantable drug delivery device using a mobile computing device that include establishing a connection with a telemetry unit configured for wireless communication with the implantable drug delivery device, displaying user-selectable drug delivery settings for the implantable drug delivery device, receiving at least one selection of a drug delivery setting, translating the received selection into a signal format readable by the telemetry unit, and sending the translated signal to the telemetry unit to program the implantable drug delivery device. Further embodiments include telemetry units for communication with an implantable drug delivery device, and patient programmers and a method for patient modification to a programmed drug delivery regimen.