An instrument having a dosing unit connected to a handle or housing of instrument. The dosing unit may include a reusable actuator with a drive unit and a single-use cartridge. The Cartridge may have a cylinder and a piston, and may be filled by a user prior to the intervention or may be prefilled by the manufacturer. The dosing unit is brought into an open position offset from housing by, for example, operating a latch slider and pulling the dosing unit in a proximal direction. After insertion of the cartridge, the dosing unit may be moved toward housing and the latched slider will lock the dosing unit into a closed position.

An arrangement for a drug delivery device is provided, the arrangement comprising: a housing having a proximal end and a distal end, a dose setting member which is rotatable relative to the housing for a dose setting operation in order to set a dose of drug to be delivered, a tracking member, and a guide track. Wherein the tracking member is operatively coupled or coupleable to the dose setting member, or wherein b) the dose setting member is a tracking member. The guide track is configured to form a guiding interface to guide and/or drive movement of the tracking member. The tracking member can be displaced towards an axial tracking member end position during the dose setting operation, wherein the distance by which the tracking member is displaced towards the axial tracking member end position depends on the size of the set dose.

An autoinjector for discharging one or more liquid products includes: a housing containing a multichamber product container, which includes a syringe body and an injection needle rigidly arranged at the distal end of the syringe body. The syringe body includes a first chamber for a first liquid product, a second chamber for a second liquid product, and a bypass for fluidically connecting the first chamber and second chamber. The bypass is formed in or on the syringe body in the form of a curved section protruding radially outwards, and two plungers are arranged in the syringe body in an axially movable manner.

The present invention relates to a medicament injector including an applicator with a cartridge-accepting receptacle, and interchangeable, pre-filled medicament-containing cartridges. Each cartridge includes a barrier member having a closed position in which access to the medicament is inhibited. The barrier member is movable from the closed position to an open position, in which the medicament is accessible via the applicator for administration, when the cartridge is inserted into the receptacle. The barrier member is moves back to the closed position when the cartridge is automatically removed from the receptacle once the medication is delivered. This allows for plurality of pre-filled medicament cartridges to be selected on demand via a need-based scenario for quick assembly with the medicament injector for use in various clinical scenarios to reduce the bulk, errors, complexity, and steps in medicament delivery while increasing the versatility, safety, and speed of medicament delivery in time critical situations.

A drug delivery device is provided, including a housing, a drug storage container, a plunger, a plunger biasing member, a releaser, and a shock absorber. The housing defines a longitudinal axis and has an opening. The drug storage container includes a barrel, a stopper, and a delivery member, where the stopper is movably positioned within the barrel. The delivery member is positioned at a distal end of the barrel and has an insertion end configured to extend at least partially through the opening during a delivery state. The plunger is moveable toward the distal end of the drug storage container to engage the stopper and expel a drug from the drug storage container through the delivery member. The plunger biasing member is coupled with the plunger and configured to urge the plunger toward the distal end of the drug storage container. The releaser member has a first position wherein the releaser member prevents the plunger from moving into the delivery state and a second position wherein the releaser member does not prevent the plunger from moving into the delivery state. The shock absorber is configured to absorb an impact force and prevent unintended movement of the releaser member.

An auto injector for administering injection of a medicament from a cartridge containing the medicament, includes a housing, a cartridge receiver with a cartridge receiver compartment configured to receive a cartridge assembly including at least one cartridge retention member when the cartridge assembly is inserted through a cartridge receiver opening along a longitudinal axis in a receiving direction, an elongated ejector including an ejector support face for supporting the cartridge or the cartridge assembly and a longitudinal ejector slot extending towards the ejector support face from an ejector rest portion, wherein the elongated ejector is suspended to move along the longitudinal direction and is spring-loaded in the direction opposite of the receiving direction, and an ejector lock supported for turning at least a fraction of a revolution and maintained in a longitudinal position relative to the housing.

A syringe system includes a syringe and a pressurization device for a syringe. The pressurization device for a syringe is configured so that the plunger advances by a forward rotation of the plunger, and the plunger retracts by a reverse rotation of the plunger. The plunger is advanceable by pressing the gasket at the time of the forward rotation and is retractable with respect to the barrel without pulling the gasket in the proximal end direction at the time of the reverse rotation.

This disclosure relates to pre-filled syringes and their methods for use and injection. The embodiments provide a pre-filled syringe system for controlled depth of injection in a subject, including a pre-filled syringe having a needle tip and a plunger for injecting the contents of the pre-filled syringe; a housing for holding the pre-filled syringe and needle tip in a defined position for a depth of injection; and a needle shield mounted on the housing for releasable movement from a locked injection position to a shield position, wherein after the needle shield is moved into the locked injection position with the needle tip extended out of the needle shield and pre-filled syringe system, the needle can be inserted into the subject at a defined depth of injection. The embodiments further provide methods of injecting a subject using a pre-filled syringe system, including providing a pre-filled syringe system having a housing, a needle shield mounted on the housing, and a pre-filled syringe with a needle tip; moving the needle shield mounted on the housing into a locked injection position to extend the needle lip of the pre-filled syringe and system at a defined length out of the needle shield and prc-filled syringe system; inserting the needle tip of the pre-filled syringe and system into a subject at a defined injection depth, and injecting the contents of the pre-filled syringe and system into the subject.

An auto injector (4) for administering injection of a medicament from a cartridge containing the medicament, the auto injector (4) comprising: a housing (6); a cartridge receiver (300) with a cartridge receiver compartment (302) configured to receive a cartridge assembly (600), with at least one cartridge retention member (808), when inserted through a cartridge receiver opening (301) along a longitudinal axis (L) in a receiving direction; wherein the cartridge receiver (300) has a passage (316) through which the at least one cartridge retention member (808) travels at least in the receiving direction, and a member (312) preventing movement beyond a retention position in a direction opposite of the receiving direction; an elongated ejector (200) that is configured with: an ejector support face (204) for supporting the cartridge or cartridge assembly (600), a longitudinal ejector slot (228) extending towards the ejector support face (204) from an ejector rest portion (206); wherein the elongated ejector (200) is suspended to move along the longitudinal direction and is spring-loaded in the direction opposite of the receiving direction; and an ejector lock (212) supported for turning at least a fraction of a revolution and maintained in a longitudinal position relative to the housing (6); wherein the ejector lock (212) has a ejector lock support portion (214) that is configured to align with and slide along the longitudinal ejector slot (228) at a first angle and to be brought to align with the ejector rest portion (206) at a second angle.

The present disclosure refers to a housing element for a drug delivery device. The housing element comprises longitudinal axis and defines an interior space for receiving components of a drive mechanism of the drug delivery device and at least a portion of a cartridge of the drug delivery device. The housing element comprises an engagement feature for axially constraining the housing element to a cartridge holder of the drug delivery device. In order to constrain the cartridge in the housing element, it further comprises at least one crush web protruding radially inwards into the interior space. The at least one crush web is angled relative to the longitudinal axis of the housing element by at least 3° such that when the cartridge is introduced into the interior space the at least one crush web folds radially outwards.