An auto injector for administering injection of a medicament from a cartridge containing the medicament, includes a housing, a cartridge receiver with a cartridge receiver compartment configured to receive a cartridge assembly including at least one cartridge retention member when the cartridge assembly is inserted through a cartridge receiver opening along a longitudinal axis in a receiving direction, an elongated ejector including an ejector support face for supporting the cartridge or the cartridge assembly and a longitudinal ejector slot extending towards the ejector support face from an ejector rest portion, wherein the elongated ejector is suspended to move along the longitudinal direction and is spring-loaded in the direction opposite of the receiving direction, and an ejector lock supported for turning at least a fraction of a revolution and maintained in a longitudinal position relative to the housing.

Drug delivery devices and related methods of assembly are disclosed. The drug delivery device may include a main housing having an exterior surface releasably attachable to a patient, a container disposed in an enclosed space defined by an interior surface of the main housing, and a drive assembly. The container may include a reservoir containing a drug and a stopper. The drive assembly may include drive housing and a tether which slidably engages and is pulled taut against a guide surface of the drive housing. A first end of the tether may be wound around a capstan which is mounted rotatably relative to the drive housing. A second end of the tether may be operably connected to a stopper biasing member. The tether may initially retain the stopper biasing member in an energized state. When released, the stopper biasing member may expand to move the stopper through the reservoir.

An auto injector (4) for administering injection of a medicament from a cartridge containing the medicament, the auto injector (4) comprising: a housing (6); a cartridge receiver (300) with a cartridge receiver compartment (302) configured to receive a cartridge assembly (600), with at least one cartridge retention member (808), when inserted through a cartridge receiver opening (301) along a longitudinal axis (L) in a receiving direction; wherein the cartridge receiver (300) has a passage (316) through which the at least one cartridge retention member (808) travels at least in the receiving direction, and a member (312) preventing movement beyond a retention position in a direction opposite of the receiving direction; an elongated ejector (200) that is configured with: an ejector support face (204) for supporting the cartridge or cartridge assembly (600), a longitudinal ejector slot (228) extending towards the ejector support face (204) from an ejector rest portion (206); wherein the elongated ejector (200) is suspended to move along the longitudinal direction and is spring-loaded in the direction opposite of the receiving direction; and an ejector lock (212) supported for turning at least a fraction of a revolution and maintained in a longitudinal position relative to the housing (6); wherein the ejector lock (212) has a ejector lock support portion (214) that is configured to align with and slide along the longitudinal ejector slot (228) at a first angle and to be brought to align with the ejector rest portion (206) at a second angle.

The invention relates to an injection device (1) for injecting a pharmaceutical substance, having a proximal part (5) which has a drive (7) to implement an injection, and having a distal part (13) which is configured to accommodate an injection loading part (3), which has a packaging means receiving part (17) and a primary packaging means (23) which held in the packaging means receiving part (17) and in which a pharmaceutical substance is received, wherein the pharmaceutical substance can be injected from the injection loading part (3) when the injection loading part (3) is arranged in the distal part (13), wherein the distal part (13) is designed in such a way that the injection loading part (3) can be inserted axially into the distal part (13), and wherein the injection device (1) has a screen (15) which is designed and arranged in such a way that an injection needle (25) of the injection loading part (3) is concealed from a user during use of the injection device (1).

Drug delivery devices and related methods of assembly are disclosed. The drug delivery device may include a main housing having an interior surface defining an enclosed space, and an exterior surface releasably attachable to a patient. A container may be disposed in the enclosed space and include a reservoir containing a drug and a stopper. A drive assembly may also be disposed in the enclosed space and configured to move the stopper through the reservoir to expel the drug from the reservoir. The drive assembly may include a rotational power source and a gear module. The gear module may include a mounting plate and a plurality of gears rotatably connected to the mounting plate. Furthermore, the mounting plate may be separate from the main housing.

The present invention relates to a spring-loaded medical injection device for automatically ejecting set doses of a drug having an injection button (10). The injection device comprises a housing having a dose setting member (20) for straining an injection spring when setting the size of the dose to be injected and a release element (30) for releasing the strained injection spring to eject the set dose. The injection button (10) is movable in a distal direction against the bias of a return spring (1) and movable in a proximal direction by the force of the return spring (1). Further, the injection button (10) moves with it the release element from a first position to a second position. The release element (30) is further coupled to the injection button (10) by a plurality of fingers (31, 15) which disengages the injection button (10) from the release element (30) in the first position and engages the injection button (10) with the release element (30) in the second position, such that the injection button (10) can move a distance axially independently of the release element (30) in the first position and the injection button (10) and the release element (30) move axially together in the second position.

Drug delivery devices, sealing members for containers housed within such drug delivery devices, and related methods of assembly are disclosed. The drug delivery device may include a housing, a container disposed in the housing and having an interior volume, a drug disposed in the interior volume, and a septum. The container may have an opening formed in an end surface and which communicates with the interior volume. The septum may include a proximal end inserted through the opening into the interior volume of the container. Additionally, the septum may include a distal end having a flange disposed outwardly of the proximal end and contacting the end surface of the container. At least an end portion of the flange may be made of a material that is permeable to a gaseous sterilizing agent.

The present disclosure relates to an injection device for setting and dispensing of a dose of a medicament, the device comprising: an elongated main housing to accommodate a cartridge filled with the medicament and defining an axial direction, a piston rod arranged inside the main housing and extending in axial direction along a first axis to operably engage with a piston of the cartridge, a reset member axially displaceable inside the main housing between a proximal operating position and a distal reset position along a second axis radially offset from the first axis to switch the device between a reset mode and an operating mode, a cartridge holder releasably attachable to a distal end of the main housing on the first axis to accommodate a distal end of the cartridge, wherein the cartridge holder comprises a sidewall portion with a radially outwardly protruding lock member to axially engage with the reset member located radially adjacent the cartridge holder.

An injection device has a plunger for displacing a stopper in a syringe or carpule, a holder for the plunger, a drive for the axial displacement of the holder of the plunger, and a control device functionally assigned to the drive. The plunger, or at least a subcomponent thereof, relative to the holder, the holder is able to move over a limited distance relative to the plunger or a subcomponent thereof, opposing a pretensioning force, in that a sensor device is included which detects the relative position of the plunger, or at least a subcomponent thereof, relative to the holder, which comprises at least one sensor element which works together with the control device. The control device is designed such that, upon activation of the sensor element, the speed of advancement of the holder of the plunger is at least reduced.

Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a subject. The present disclosure comprises apparatus for the controlled administration of the therapeutic agent through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.