A suturing system including an elongate distal member, an elongate proximal member proximal the elongate distal member, and a needle guide disposed between the elongate distal member and the elongate proximal member. A plurality of needles with a needle tip of each needle of the plurality of needles are orientated generally proximally toward a single opening in a distal end of the elongate proximal member. When the needle tip of each of the plurality of needles is at least partially disposed within the single opening, a portion of each needle of the plurality of needles, proximal a distal end of the needle guide, being radially separated by a distance less than a diameter of the elongated proximal member.

The invention relates to an injection device for injecting a liquid drug. The injection device comprises a housing assembly supporting a non-removable cartridge having an interior chamber containing the liquid drug to be injected and a reusable needle cannula connected to the cartridge. A needle shield assembly provided with a cleaning chamber containing a volume of a cleaning agent for cleaning at least the distal tip of the needle cannula between subsequent injections is further provided. The needle shield assembly is axially movable in a proximal direction in relation to the housing assembly from a first position to a second position upon rotation of at least a part of the needle shield assembly, wherein the first position is a position in which the distal tip of the needle cannula is located inside the cleaning chamber thereby cleansing the distal tip of the needle cannula, and the second position is a position in which the distal tip of the needle cannula is located outside and distal to the cleaning chamber for equalizing the pressure in the cartridge.

A safety needle having a rigid outer structure within which there is a cannula holding element of being movably coupled to an injector pen for a drug is provided. The cannula holding element supports a cannula having a first extremity and a second extremity for administration of the drug. A moving protective element associated with the rigid structure, covers the second extremity of the cannula after administration, with provision being made for a deforming member capable of deforming the cannula after administration of the drug so that the second extremity of the cannula remains within the protective element. The deforming member is associated with the protective element and is capable of rotating autonomously with respect thereto after administration of the drug to deform the cannula.

Systems and methods are disclosed for bending a needle. A device for bending a needle is disposed around a needle and coupled to an injection device. A force is exerted on the needle to cause the needle to bend upon a bending trough of the device. The device includes a proximal end to interface with the injection device and a distal end having the bending trough. The bending trough is configured to improve bending and prevent breaking of the needle by providing a rounded surface upon which the needle is bent.

An injector includes an injector housing, an activation button assembly movably mounted to the injector housing and operatively connected to the injection needle, and a cartridge door movably mounted to the injector housing between an open position and a closed position. A deflectable interference member engaging the rear end flange of the cartridge has a resting position configured to limit an insertion depth of a cartridge into an interior channel of the cartridge door to a sealed position, wherein the cartridge piercing needle does not fully penetrate a pierceable septum of the cartridge. The cartridge door includes an interior channel having a cartridge mounted therein. The cartridge includes a substance to be dispensed. The substance includes an anti-C5 antibody or antigen binding fragment thereof, and optionally further includes a recombinant human hyaluronidase enzyme. A method of treating a complement associated condition using an injector thereof. A method of dispensing a substance from an injector thereof.

A safety needle having a rigid outer structure within which there is a cannula holding element of being movably coupled to an injector pen for a drug is provided. The cannula holding element supports a cannula having a first extremity and a second extremity for administration of the drug. A moving protective element associated with the rigid structure, covers the second extremity of the cannula after administration, with provision being made for a deforming member capable of deforming the cannula after administration of the drug so that the second extremity of the cannula remains within the protective element. The deforming member is associated with the protective element and is capable of rotating autonomously with respect thereto after administration of the drug to deform the cannula.

A safety syringe comprising a needle redirection device that is desirably configured to bend the needle shaft forwardly of the barrel following an injection to thereby redirect the needle tip from a first position where it projects forwardly in coaxial alignment with the syringe barrel to a second position where the needle tip is covered or protected from incidental or accidental contact and associated needle sticks. Both sliding and pivoting embodiments are disclosed.

A retractable needle assembly (1) is disclosed comprising a body portion (10); a needle (50) having a forward end (52) and being movable between an operable orientation in which the forward end projects forwardly from the body portion, and a safe orientation in which said forward end (52) is retracted into the body portion (50). The needle assembly further comprises a deflector (70) mounted in the body portion (50), which is moveable between a first position and a second position, wherein the movement of the deflector (70) between its first and second position urges the needle into its safe orientation, the deflector being biased towards the second position; a latching mechanism which holds the deflector in the first position; and an actuator (90), operable to release the latching mechanism.

A suturing system including an elongate distal member and an elongate proximal member proximal the elongate distal member, the elongate proximal member having a lumen. A needle deployment actuator extends to the elongate distal member and is configured to initiate proximal movement of a needle toward an opening of the elongate proximal member. A guide is disposed within the elongate proximal member, a perimeter of the guide forming a plurality of needle receiving gaps that, when viewed in cross-section, are circumferentially spaced about the deployment actuator with a portion of the guide disposed between adjacent needle receiving gaps extending outwardly towards a wall of the lumen of the elongate proximal member.

A retractable needle assembly comprises a body portion, a needle having a patient end and being movable between an operational position in which the needle extends along a longitudinal needle axis with the patient end projecting forwardly from said body portion, and a safe position in which said patient end is retracted into said body portion, a deflector element rotatable about a deflector rotary axis generally perpendicular to said needle axis to move the needle to its safe position, and a manually operated deflector lever connected to or forming part of said deflector element, the deflector lever projecting from said body portion and intersecting a plane perpendicular to the deflector rotary axis and containing the needle axis.