A face engaging device such as a nozzle, facemask, etc., may include a housing including a fluid channel extending through the housing to an opening configured to be placed in fluid communication with the mouth of a user. The housing may include a first surface configured to be placed in contact with the skin of the user and a second surface exposed to the fluid channel. The face engaging device may also include a thermal actuator supported by the housing and including a first heat transfer surface position on the first surface, where the first heat transfer surface is configured to apply a thermal profile to the skin of the user when the opening is placed in fluid communication with the mouth of the user.

A vestibular neurostimulation device, which may include first and second electrodes; first and second thermoelectric devices thermally coupled, respectively, to first and second earpieces that are configured to be insertable into respective ear canals of a patient; and a controller comprising a waveform generator. The waveform generator may be is configured to deliver a modulated electric signal to the patient through galvanic vestibular stimulation (GVS) using the first and second electrodes and to deliver a time varying thermal waveform to the patient through caloric vestibular stimulation (CVS) using the first and second earpieces simultaneous with the delivery of the modulated electrical signal through GVS. The CVS and/or GVS may be configured to increase a passage of insulin-like growth factor 1 (IGF-1) through a blood-brain-barrier.

A device is described for delivering a therapeutic vibration to a body. The device may include at least two motors in a housing with unbalanced masses coupled to their axles, such that vibration of the masses causes the two motors and housing to vibrate at a beat frequency 80. The motors and housing may be coupled to the body via a platform which places the motors and housings at or near a resonant structure in the body, creating a coupled oscillation between the platform and the body. The vibration may be based on the input signal, such that the system applies the vibration based on the input signal to the user, wherein the signal may be an audio or video signal. The system may be configured to measure and manipulate the flow of cerebral spinal fluid.

Systems and methods for improving behavioral therapies encompassing therapies wherein a perceptual stimulus is administered to a subject or a motor behavior is performed by the subject. Such administration of perceptual stimuli or motor performance is paired with the delivery of vagus nerve stimulation to the subject. The vagus nerve stimulation is timed with the sensory stimulus administration or motor performance in a temporal alignment that maximizes neuroplasticity and performance. Systems for performance of the method and associated software are also disclosed

The methods, systems and devices provided herein relate to sleep-aid. Some embodiments include a vibration source and/or a sound source. In some embodiments, the vibration source and/or sound source emit vibrations and/or sounds that stimulate a subject's vagus nerve, or another nerve, to induce sleep or relaxation in the subject.

An intelligent psychological assessment and intervention system based on an independent space, comprising a psychological intervention cabin and a central database which achieves data interaction with the psychological intervention cabin. The psychological intervention cabin comprises a housing, a data acquisition module, a data processing module, and an intervention module; the data acquisition module acquires physiological and psychological data of a subject; the data processing module performs operations on the acquired data, establishes a multi-dimensional state point of the subject according to a mathematical model of the data processing module, matches it with data in the central database, finds a suitable intervention procedure for the subject, and guides the intervention module to carry out intervention; in the intervention process, the data acquisition module continuously acquires the physiological and psychological data of the subject, and the data processing module forms a new multi-dimensional state point according to new data and re-matches it to adjust the intervention procedure. By repeating this cycle, the intervention procedure is continuously adjusted in the intervention process to seek a most suitable intervention solution for the subject, and an optimal intervention effect is achieved.

A method of introducing a vapor of at least one substance into an inhalation flow path of a respiratory organ is provided. The method describes providing a carrier conformable to a surface of skin; providing the carrier with at least one substance; providing a barrier coupled to a surface of the carrier, the barrier being substantially impermeable to the substances carried by the carrier; providing a polyethylene coated material disposed within or atop the barrier and configured as a clamp for a septum of a user, wherein the polyethylene coated material is heat sealed within the barrier; and engaging the carrier to the surface of skin proximate an inhalation flow path of a respiratory organ with the barrier adapted to be interposed between the carrier and the skin to prevent the one or more substances from contacting the skin; wherein the substance is volatile and/or non-volatile; wherein the carrier is impregnated with nanocapsules during production. A vehicle for introducing a vapor is also provided.

A method of neurostimulation may include delivering an electrical signal to a plurality of electrodes connected to a patient. The electrical signal may include an amplitude and a carrier frequency. The method may include modulating the electrical signal based on an audio waveform. In some embodiments, the modulating may include modulating at least one of the amplitude and the carrier frequency based on the audio waveform to modulate the electrical signal.

A method of transplanting a sleep state of a first subject (donor) to a second subject (recipient) comprising: capturing a sleep state of the first subject represented by brain activity patterns; and transplanting the sleep state of the first subject in the second subject by inducing the brain activity patterns in the second subject.

A fragrance suitable for a user can be provided. A mobile terminal includes: an acquisition unit that acquires a psychosomatic state from a physiological index of a user; an input unit that inputs future information of the user; a determination unit that determines a recipe including one or more types and a mixing ratio of one or more perfumes based on the psychosomatic state and the future information; and a communication unit that transmits the recipe to a fragrance generation device.