A vapor delivery system is provided that may include any of a number of features. One feature of the vapor delivery system is that it can apply condensable vapor energy to tissue, such as a prostrate, to shrink, damage, or denature the prostate. In some embodiments, the vapor delivery system can include safety features including prostate capsule detection, needle tracking, and treatment tracking. Methods for safe and effective treatment of prostate tissues are presented.

A therapeutic device (1) has a stem (3) having a distal end (60) configured for insertion in a patient's ear canal with latching by suction to the tympanic membrane so that there is no relative movement despite patient head movement. A needle (63) punctures the membrane after suction is applied by negative pressure via a lumen (66). The needle tip is located within a suction cup which grips the membrane. A hand-held control device (2) is coupled to the stem and has a user-actuated controller (8) for controlling application of negative pressure (7) to the suction lumen.

A device for expanding tissue comprises at least one fluid delivery tube and at least one fluid delivery element in fluid communication with the at least one fluid delivery tube. The at least one fluid delivery tube comprises a proximal end, a distal end, and a lumen therebetween. The device is constructed and arranged to perform a near full circumferential expansion of luminal wall tissue. Systems and methods are also provided, including a system for expanding tissue layers and treating tissue proximate to the expanded tissue layers.

The present invention describes a method and kit for performing a prostate medical or surgical treatment.

The present disclosure relates generally to devices, systems, and methods for minimally invasive medical treatment, methods of diagnosing and treating diseases, and to visualizing, accessing, and perform interventions involving the thoracic duct.

Disclosed are steerable needles having a shaft that can be controllably buckled, a steering head positioned at a distal end of the shaft, a transmission for controlling the orientation of the steering head, and a base at the end of the shaft, the base optionally comprising a controller for controlling the transmission. Also disclosed are methods of using the disclosed steerable needles.

The present disclosure discusses a devices, systems and methods for transvascular, transvenous and/or transdural access, to the brain parenchyma, subarachnoid or subdural spaces. In some embodiments, the disclosed systems and methods may be used for local drug delivery, tissue biopsy, nanofluidic or microelectronic device/component delivery/insertion/implantation, in situ imaging, ablation of abnormal brain tissue and the like. Embodiments of the present disclosure include an access catheter system for extravascular procedures in the brain having an elongate, flexible tubular body, with at least one lumen extending axially there through between a proximal end, and a distal end. The access catheter system may include a side exit port and a distal end port. Further, the access catheter system may include a selective deflector positioned within the lumen configured to deflect a procedure catheter and permit a guide catheter.

A catheter system for accessing the central venous system through an occlusion in the neck region.

A catheter may be used for treating chronic venous insufficiency (CVI) by remodeling a venous valve within a vein. The catheter is advanced through the vein to a position proximate the venous valve, the catheter including a hollow needle extendable out a first side wall of the catheter and an inflatable balloon located on a second, opposing, side wall of the catheter. The inflatable balloon is inflated in order to urge the catheter towards a vessel wall opposite that of the inflatable balloon. The hollow needle is advanced at least partially into the vessel wall opposite that of the inflatable balloon and a bulking agent is injected near the venous valve in order to remodel the venous valve. The bulking agent may be injected within a subintimal space within the vessel wall, or into an advential space outside of the vessel wall.

The present disclosure discusses a devices, systems and methods for transvascular, transvenous and/or transdural access, to the brain parenchyma, subarachnoid or subdural spaces. In some embodiments, the disclosed systems and methods may be used for local drug delivery, tissue biopsy, nanofluidic or microelectronic device/component delivery/insertion/implantation, in situ imaging, ablation of abnormal brain tissue and the like. Embodiments of the present disclosure include an access catheter system for extravascular procedures in the brain having an elongate, flexible tubular body, with at least one lumen extending axially there through between a proximal end, and a distal end. The access catheter system may include a side exit port and a distal end port. Further, the access catheter system may include a selective deflector positioned within the lumen configured to deflect a procedure catheter and permit a guide catheter.