A peritoneal dialysis (PD) catheter is disclosed. In various embodiments, the PD catheter includes an improved intraperitoneal drain array as well as an improved anchor for use in placement of the device.

Various exemplary methods and devices (10, 110, 210) for delivering liquid therapeutic agents in solid tumors are provided. In general, a delivery device configured to deliver a liquid therapeutic agent into a solid tumor or other soft tissue can be configured to compress tissue and seal any fluid gaps around the delivery device during the delivery of the liquid therapeutic agent. In an exemplary embodiment the delivery device includes three elongate tubular shafts (12, 14, 16, 112, 114, 116, 212, 214, 216) configured to move longitudinally relative to one another. The elongate tubular shafts are configured to cooperate with one another to deliver the liquid therapeutic agent through a passageway of the delivery device to the solid tumor or other soft tissue and seal any fluid gaps around the delivery device while the liquid therapeutic agent is delivered into the solid tumor or other soft tissue.

A device for guiding and supporting a stent delivery catheter and other catheters is disclosed. The device may comprise a tubular guiding member and an elongated positioning member extending in a proximal direction beyond the tubular guiding member for advancing and retracting the tubular guiding member in distal and proximal directions. A distal portion of the elongate positioning member may be coupled to the proximal portion of the tubular guide. In embodiments, the device includes a ribbon having a distal portion and a proximal portion. In embodiments, the distal portion of the ribbon extends distally into the tubular guiding member and the proximal portion of the ribbon overlays an inner surface of the elongate positioning member. Methods for making medical devices and portions of medical devices (e.g., intravascular catheters, catheter shafts, and tubular guiding members) are also provided. Example methods may include providing a first ribbon comprising one or more thermoplastic materials and a piece of shrink tubing defining a shrink tube lumen and forming a first assembly by positioning the first ribbon inside the shrink tube lumen and urging the first ribbon to assume a tubular shape in which the first ribbon defines a ribbon lumen. A second assembly may be formed by loading an inner tubular member over a mandrel and forming or placing a support structure over an outer surface of the inner tubular member. A third assembly may be formed by inserting the second assembly into the ribbon lumen defined by the first ribbon of the first assembly. The third assembly may be heated to a process temperature.

An introducer set (1) for providing vascular access in a patient's body comprises an introducer sheath (10) and a dilator (20). The introducer sheath (10) has a tubular body (11) made of flexible material with a distal portion (12), a proximal portion (13) and an inner surface, the proximal portion (13) being configured to be inserted into a patients vessel to allow a medical device (100) to be inserted through the introducer sheath (10) into the patient's vessel. At least one of the dilator (20) and the introducer sheath (10) comprises a stiffening structure (25) imparting stiffness to the tubular body (11) of the introducer sheath (10), wherein said stiffening structure (25) can be released, removed or otherwise deactivated.

A cannula for moving fluids between a pump and the circulatory system of a patient. The cannula includes a liner having an intermediate portion between a proximal portion and a distal portion, and a lumen extending between the proximal and distal portions. At least the intermediate portion of the liner is constructed from a tissue in-growth material for supporting the growth of endothelial cells. A jacket surrounds at least part of the liner.

Some embodiments of a medical system include a catheter device, such as an intravenous cannula device, having an external anchor device and a subcutaneous anchor device to secure a distally extending cannula of the device in a selected position relative to a skin penetration point.

An example catheter assembly includes a first catheter body portion defining a first lumen and a plurality of sidewall openings open to the lumen and configured to at least one of introduce fluid into a patient or remove fluid from the patient. The catheter assembly further includes a second catheter body portion defining a second lumen, a first cuff proximal to a distal end of the first catheter body portion, a second cuff distal to a proximal end of the second catheter body portion, and a connector configured to mechanically connect the first and second catheter body portions between the first and second cuffs and to fluidically connect the first and second lumens. A distance between the first and second cuffs is modifiable by at least modifying one of a length of the first catheter body portion or a length of the second catheter body portion.

Some embodiments of a medical anchor device include an elongate body coupled with deployable subcutaneous anchors to secure a catheter instrument (or other medical instrument) in place relative to a skin penetration point. In some circumstances, the elongate body may be in the form of catheter hub body, and the subcutaneous anchors can be deployed from the hub body by adjustment of a movable actuator. A locking member can interact with the actuator so as to retain the actuator in the deployed orientation during the medical procedure.

Aspects herein relate to systems and methods for delivery of biologic agents to the central nervous system. In various embodiments, a method of administering a therapeutic agent to the central nervous system (CNS) is included. The method can include injecting a therapeutic agent into a first cerebrospinal fluid (CSF) region of the subject. The method can further include establishing fluid communication between a fluid reservoir and a second cerebrospinal fluid (CSF) region of a subject, the fluid having a hydraulic pressure at or above an intracranial pressure. The method can further include infusing a hyperosmotic fluid systemically. Other embodiments, including kits and systems are also included herein.

The present invention discloses a catheter system, comprising: a catheter head having a lumen, a proximal end and a distal end, and an opening positioned at a bottom of the distal end; and a rotatable inner tube having a lumen positioned in the lumen and at a proximal end of the catheter head, the inner tube including a front end having an arcuate opening; wherein the rotatable inner tube can be rotated so that the arcuate opening thereon can be made to engage or disengage with the opening at the bottom of the distal end of the catheter head. The invention also provides a catheter system and method for re-entry of a vascular false lumen into a true lumen in a quick, accurate and low-risk way. The catheter system for re-entry of a vascular false lumen into a true lumen in a quick, accurate and low-risk way effectively solve the problems of difficult operation, inaccurate positioning, long operation time and easiness to cause acute occlusion and internal hemorrhage of the branch vessel when the guidewire is re-entering the true lumen in the prior art.