An ultrasound catheter with fluid delivery lumens, fluid evacuation lumens and a light source is used for the treatment of intracerebral hemorrhages. After the catheter is inserted into a blood clot in the brain, a lytic drug can be delivered to the blood clot via the fluid delivery lumens while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the fluid evacuation lumens.

An ultrasound scanning apparatus comprises an ultrasound scanning unit, an ultrasound controller for controlling the operation of the ultrasound scanning unit, detecting the operation state of the ultrasound scanning unit, generating a first enable signal when detecting that the operation state of the ultrasound scanning unit is transferred from an operating state to a non-operating state and generating a second enable signal when detecting that the operation state of the ultrasound scanning unit is transferred from the non-operating state to the operating state, and an enable output end for transmitting the first enable signal or the second enable signal to the breathing machine to control the running of the breathing machine.

A catheter system includes a medication dispenser located external to a patient. A subcutaneous port is placed internally to the patient and receives a quantity of medication. The port can be filled from a syringe or medication dispensing system. An echogenic catheter can be placed in proximity to a patient's nerve or nerve center using a point-of-care ultrasound imaging system. A method of administering a nerve block or other medication subcutaneously to a patient includes the steps of placing a subcutaneous port using ultrasound imaging for guidance and administering pharmacologic agents via a catheter connected to the port. Alternative embodiment catheter systems include echogenic tips and a stylet to facilitate accurate placement.

A skin desensitizing device for temporarily numbing and/or cooling a surface of a subject's skin. The skin desensitizing device comprises a controller, a skin-bracing interface, and at least one overloading-neural source, which includes (i) a transcutaneous electrical nerve stimulator (TENS)-like device capable of electrically stimulating superficial skin neurons of the subject's skin into a state of fibrillation, (ii) a thermoelectric device capable of cooling the subject's skin to approximately 30° F. to 38° F., and (iii) a vibration device capable of vibrating the subject's skin to overload the skin's vibration sensors.

The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

A system for stimulating body tissue may include a stimulation lead, sensors, and a control unit. The stimulation lead may include one or more energy sources. The control unit may include a processor and non-transitory computer readable medium, and an interface (e.g., touch screen interface) for receiving user inputs and communicating information to the user. The sensors may be configured to provide impedance measurements to the control unit. The control unit may calculate lung gas distributions and/or generate an image modeling lung gas distributions. Stimulation delivered by the stimulation may be adjusted based on the impedance measurements.

An intraluminal system for aspirating biological material from a lumen of a patient includes a disposable intraluminal device having a proximal portion and a distal portion. The system includes a disposable pump configured to aspirate the biological material from the lumen of the patient. The disposable pump is coupled to the proximal portion of the intraluminal device. The disposable pump comprises a pump chassis that houses: an inlet port configured to sealably attach to the proximal portion of the intraluminal device; an outlet port configured to expel the aspirated biological from the pump; and a flow controller configured to adjust a fluid flow through the pump, wherein the pump chassis is sized and shaped to be manually supported by a user.

A device for generating microbubbles may include a syringe having a barrel, a plunger and a syringe tip; a converging nozzle; and an aerator. The converging nozzle may have a coupling end, a converging tip opposite the coupling end, an exterior mating surface adjacent the converging tip, and an interior channel that fluidly couples the syringe tip and converging tip. The interior channel may have a diameter that progressively decreases from the coupling end to the converging tip. The converging nozzle may be coupled to the syringe tip. The aerator may have a retention end, a discharge end, an interior air chamber, an interior circumferential lip, and a discharge channel at the discharge end. The retention end may be coupled to the converging nozzle. The interior circumferential lip may abut the exterior mating surface. One or more air channels may fluidly couple the discharge channel and the interior air chamber.

Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.

An oxygen supply apparatus is configured to directly supply oxygen-containing gas to an user for inhalation while facilitating blood circulation of a specific portion of the user. The oxygen supply apparatus includes a power supply; an oxygen-containing gas source for providing the oxygen-containing gas; a gas catheter having one end thereof connected to the oxygen-containing gas source; an inhalator connected to the other end of the gas catheter; and a circulation facilitating device at least partially attached to the specific portion of the user. The circulation facilitating device includes a sonic oscillation circuit and a housing. The sonic oscillation circuit is configured to produce oscillation at a frequency ranging from 20 Hz to 10 MHz, and the housing encloses the sonic oscillation circuit in a watertight manner