Drug delivery devices, sealing members for containers housed within such drug delivery devices, and related methods of assembly are disclosed. The drug delivery device may include a housing, a container disposed in the housing and having an interior volume, a drug disposed in the interior volume, and a septum. The container may have an opening formed in an end surface and which communicates with the interior volume. The septum may include a proximal end inserted through the opening into the interior volume of the container. Additionally, the septum may include a distal end having a flange disposed outwardly of the proximal end and contacting the end surface of the container. At least an end portion of the flange may be made of a material that is permeable to a gaseous sterilizing agent.

Drug delivery devices, sealing members for containers housed within such drug delivery devices, and related methods of assembly are disclosed. The drug delivery device may include a housing, a container disposed in the housing and having an interior volume, a drug disposed in the interior volume, and a septum. The container may have an opening formed in an end surface and which communicates with the interior volume. The septum may include a proximal end inserted through the opening into the interior volume of the container. Additionally, the septum may include a distal end having a flange disposed outwardly of the proximal end and contacting the end surface of the container. At least an end portion of the flange may be made of a material that is permeable to a gaseous sterilizing agent.

A medical device that includes a shaft having a distal end and a cap at the distal end that defines a reservoir for storing a material. The medical device includes a deployment mechanism configured to eject the material from the reservoir, and the deployment mechanism is configured to apply a force to the reservoir. The cap includes a seal or a perforation that is configured to contain the material in the reservoir in the absence of the force applied by the deployment mechanism to the material.

Drug delivery devices, sealing members for containers housed within such drug delivery devices, and related methods of assembly are disclosed. The drug delivery device may include a housing, a container disposed in the housing and having an interior volume, a drug disposed in the interior volume, and a septum. The container may have an opening formed in an end surface and which communicates with the interior volume. The septum may include a proximal end inserted through the opening into the interior volume of the container. Additionally, the septum may include a distal end having a flange disposed outwardly of the proximal end and contacting the end surface of the container. At least an end portion of the flange may be made of a material that is permeable to a gaseous sterilizing agent.

A handle for an applicator of coloured liquid to skin is provided. The applicator comprises a needle and a needle actuator. The handle comprises a handle body having top and bottom portions. The top portion is engagable with the needle actuator and having a top opening for receiving a drive shaft of the needle actuator. The bottom portion is engagable with a needle module comprising the needle and having a bottom opening for receiving a needle shaft of the needle. The handle also comprises a reciprocally movable interface sealingly affixed to an internal surface of the handle body. The interface separates the bottom opening from the top opening so as to prevent fluid communication from the bottom opening to the top opening, and is configured to abut the drive shaft and the needle shaft during use to allow the drive shaft to indirectly drive the needle shaft.

A pre-filled medical delivery assembly assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient may include a multi-bevel cannula piercing element such as for rotational axial engagement to pierce a seal of the BFS vial.

A handle for an applicator of coloured liquid to skin is provided. The applicator comprises a needle and a needle actuator. The handle comprises a handle body having top and bottom portions. The top portion is engagable with the needle actuator and having a top opening for receiving a drive shaft of the needle actuator. The bottom portion is engagable with a needle module comprising the needle and having a bottom opening for receiving a needle shaft of the needle. The handle also comprises a reciprocally movable interface sealingly affixed to an internal surface of the handle body. The interface separates the bottom opening from the top opening so as to prevent fluid communication from the bottom opening to the top opening, and is configured to abut the drive shaft and the needle shaft during use to allow the drive shaft to indirectly drive the needle shaft.

A medical device that includes a shaft having a distal end and a cap at the distal end that defines a reservoir for storing a material. The medical device includes a deployment mechanism configured to eject the material from the reservoir, and the deployment mechanism is configured to apply a force to the reservoir. The cap includes a seal or a perforation that is configured to contain the material in the reservoir in the absence of the force applied by the deployment mechanism to the material.

A medical device that includes a shaft having a distal end and a cap at the distal end that defines a reservoir for storing a material. The medical device includes a deployment mechanism configured to eject the material from the reservoir, and the deployment mechanism is configured to apply a force to the reservoir. The cap includes a seal or a perforation that is configured to contain the material in the reservoir in the absence of the force applied by the deployment mechanism to the material.