The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO.sub.2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO.sub.2-to-NO reactor cartridge and/or a breakthrough of NO.sub.2, and providing an indication of the remaining useful life and/or breakthrough.

A surgical fluid management system includes a console and a cassette for delivering fluids to a surgical site. The console has a pump rotor and a pressure-sensing membrane. The cassette has a cassette housing, a flexible fluid delivery tube in the housing. The flexible fluid delivery tube has a lumen configured to interface with the pump rotor and to deliver a flow of fluid from a fluid source as the rotor is rotated. A pressure-transmitting membrane is located in a wall of the cassette housing and in fluid communication with said fluid delivery lumen. The pressure-transmitting membrane flexes outwardly in response to a positive pressure in the lumen and flexes inwardly in response to a negative pressure in the lumen. The pressure-transmitting membrane detachably adheres to or presses against the pressure-sensing membrane to cause the pressure-sensing membrane to move in response to pressure changes in the flexible fluid delivery tube.

In various examples, a medical device is configured to be at least partially insertable within a patient. The medical device includes a first elongate member including a sidewall surrounding and defining a lumen extending through the first elongate member between a first proximal end and a first distal end. A second elongate member is sized and shaped to fit within the lumen of the first elongate member. A coil is disposed within the sidewall of the first elongate member, wherein the coil is configured to sense a position of the second elongate member with respect to the coil. In some examples, the first elongate member includes a catheter, and the second elongate member includes a guidewire.

Methods and systems are provided for anesthetic agent leakage diagnostics. In one embodiment, a method for diagnosing leaks in an anesthetic vaporizer includes calculating a leakage rate based on measurements of an anesthetic agent level in a sump of the anesthetic vaporizer, the measurements received from a fluid level sensor at a first time and a second time, and outputting a maintenance alert responsive to the leakage rate exceeding a threshold.

An appliance is provided for negative-pressure therapy of wounds on the human or animal body in which, on the one hand, a substance is delivered to a wound bed (W) and, on the other hand, fluids, in particular an exudate and the delivered substance, are aspirated from the wound bed by negative pressure. The appliance has a suction pump housing, with a suction pump arranged therein for aspirating the fluids from the wound bed (W), and a fluid collection container for collecting the aspirated fluids. Moreover, the appliance has a first measuring device and a second measuring device. The first measuring device serves to determine the quantity of the aspirated fluids, and the second measuring device serves to determine the quantity of the substance delivered to the body.

An inhalation device defines a receptacle for receiving an aerosol-forming substrate containing at least one vaporizable substance; an atomizer configured to generate an aerosol from the aerosol-forming substrate; a first sensor configured to generate a first signal or first data associated with a presence of at least one chemical substance in the generated aerosol; a second sensor configured to generate a second signal or second data associated with a further characteristic of the generated aerosol or of the aerosol-forming substrate or of the at least one vaporizable substance; and at least one controller configured to separately analyze both the first signal or first data and the second signal or second data to determine first and second analysis results, and configured to determine an operation mode of the inhalation device or to determine whether to alter an operation of the inhalation device based on both the first and second analysis results.

On-demand, hand-held vaporizer that operates primarily by convection. The vaporizer is configured to permit very rapid (e.g., within a few seconds) heating of air drawn through an oven chamber to a predetermined or selectable vaporizing temperature to vaporize a material (e.g., loose leaf plant material, etc.) that is held in the oven chamber. The vaporizer provides efficient transfer of air being heated as well as rapid delivery of vaporizable material to a user.

A data collection device (20) for attachment to an injection device (1), such as an injector pen, comprises a sensor arrangement (26) to detect movement of a movable (70) of the injection device (1) relative to the data collection device (20) during delivery of a medicament by the injection device (1), and a processor arrangement (23) configured to, based on said detected movement, determine a medicament dosage administered by the injection device (1). The processor arrangement (23) may monitor the time that has elapsed since the medicament dosage was administered, and control a display (22) to show the medicament dosage (22a) and elapsed 22 time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component (70) comprises a plurality of light barrier formations. The movable component (70) may be a number sleeve that provides a visual indication of a dose programmed into the injection device (1).

An intelligent bioelectric module for use with a drug delivery system has a case and a set of at least two electrodes in electrical communication with a detection surface of the case. The case is configured so that, in use, the detection surface comes into electrical communication with (i) a second surface of the delivery system when a first surface of the delivery system has been put into contact with a tissue surface of a human or animal subject or (ii) the tissue surface that is adjacent to a portion contacted by the first surface of the delivery system or (iii) both the second surface and the tissue surface.

Apparatus and methods are described for use with a portion of plant material that includes at least one active ingredient. A vaporizing unit includes a heating element configured to heat the plant material, and a sensor configured to detect an indication of airflow rate through the vaporizing unit. Control circuitry is configured to receive an indication of the airflow rate through the vaporizing unit, and, in response thereto, to determine a smoking profile that is desired by the user. The control circuitry drives the heating element to vaporize the active ingredient of the plant material by heating the plant material according to the determined smoking profile. The control circuitry dynamically updates the smoking profile in response to changes in airflow rate over the course of a smoking session. Other applications are also described.