A method and system for diagnosing, treating, and ameliorating sleep bruxism events using a positive airway pressure (PAP) system for treating obstructive sleep apnea to concurrently recognize bruxism events. At least one sensor is integrated into a therapy interface and/or headgear to detect physiological signals indicative of bruxism. In some exemplary embodiments, a loudspeaker and microphone are integrated into the interface, either near the nose or near the mouth of the patient. When integrated near the nose, the pair is used for acoustical rhinometry, and when integrated near the mouth, the pair is used for acoustical pharyngometry. In other exemplary embodiments, sound or vibration sensors are used to detect signals indicative of teeth grinding. In response to sensor detection of bruxism activity, the PAP system controller adjusts the PAP therapy settings or proposes alternative treatment modalities in order to stop or prevent bruxism events.

A system and method for providing sensory relief from distractibility, inattention, anxiety, fatigue, and/or sensory issues to a user in need. The user can be autistic/neurodiverse, or neurotypical. The system can be configured to connect to a datastore storing one or more sensory thresholds specific to a user of a wearable device of the system, the sensory thresholds selected from auditory, visual or physiological sensory thresholds; record, using one or more sensors of the wearable device, a sensory input stimulus to the user; compare the sensory input stimulus with the sensory thresholds to determine an intervention to be provided to the user, the intervention configured to provide the user relief from distractibility, inattention, anxiety, fatigue, or sensory issues; and provide the intervention to the user, the intervention comprising filtering, in real-time, an audio signal presented to the user or an optical signal presented to the user.

Systems, devices, and methods are provided for sensing gas bubbles within a liquid flow line, such as within a medical device. The systems, devices, and methods can measure a change in capacitance across a pair of conductive plates to calculate a volume of gas in a flow line. If a calculated volume of gas exceeds an established threshold, an alert can be sent and/or changes made to operation of the device.

An apparatus includes an occlusion device operable to fit securely in an anatomical passageway within a head of a human. The occlusion device is configured to move unitarily with the head when the occlusion device is installed in the anatomical passageway. The occlusion device is further configured to prevent passage of fluid through the anatomical passageway when the occlusion device is installed in the anatomical passageway. A position sensor is fixedly integrated into the occlusion device. The position sensor generates signals indicating a position of the occlusion device in three-dimensional space, thereby indicating the position of the head in three-dimensional space. A connector communicatively coupled to the position sensor is operable to receive and transmit the signals generated by the position sensor.

Drug delivery articles, resident articles, and retrieval systems e.g., for gram-level dosing, are generally provided. In some embodiments, the articles are configured for transesophageal administration, transesophageal retrieval, and/or gastric retention to/in a subject. In certain embodiments, the article includes dimensions configured for transesophageal administration with a gastric resident system. In some cases, the article may be configured to control drug release e.g., with zero-order drug kinetics with no potential for burst release for weeks to months. In some embodiments, the articles described herein comprise biocompatible materials and/or are safe for gastric retention. In certain embodiments, the article includes dimensions configured for transesophageal retrieval. In some cases, the articles described herein may comprise relatively large doses of drug (e.g., greater than or equal to 1 gram).

A dressing for treating tissue with negative pressure is provided herein comprising a composite of dressing layers, including a release film, a perforated coated polymer film, a manifold, and an adhesive cover. Additionally, a method of manufacturing the dressing may comprise applying a cross-linkable polymer to a polymer film, curing the cross-linkable polymer to a gel layer to form a coated polymer film, and perforating the coated polymer film to form fluid restrictions, such as slits and/or slots, though the coated polymer film.

A device for dispensing a fluid product, having a body (1) and a dispensing head (2) with a dispensing orifice (3) and axially movable. The body receives a vessel (10) containing one or two doses of product. The device has an electronic module (100) with a wireless communication module (101), a geographical location module (102), and a power source (103). The device has a sensor system (201, 202) for detecting and automatically signalling an attempt to use the device, the sensor system having a first sensor (201) arranged on the dispensing head (2) and a second sensor (202) on the body, the sensor system detecting handling representative of an attempt to use the device when the first and second sensors (201, 202) are activated simultaneously, the wireless communication module designed to make an automatic emergency call when the sensor system detects handling representative of an attempt to use the device.

Devices and methods for controlling molecular transport are disclosed herein. The devices include a membrane having a plurality of nanochannels extending therethrough. The membrane has an inner electrically conductive layer and an outer dielectric layer. The outer dielectric layer creates an insulative barrier between the electrically conductive layer and the contents of the nanochannels. At least one electrical contact region is positioned on a surface of the membrane. The electrical contact region exposes the electrically conductive layer of the membrane for electrical coupling to external electronics. When the membrane is at a first voltage, molecules flow through the nanochannels at a first release rate. When the membrane is at a second voltage, charge accumulation within the nanochannels modulates the flow of molecules through the nanochannels to a second release rate that is different than the first release rate. Methods of fabricating devices for controlling molecular transport are also disclosed herein.

A sensor for measuring the contents of a syringe or other container is described. The sensor includes a voltage source, a pair of electrodes, a measurement circuit, and an electrode shield. The voltage source is coupled to the electrodes, and the electrodes apply an electric field through at least a portion of the container or syringe. The measurement circuit measures capacitance across the electrodes. The electrode shield partially encloses the pair of electrodes. The electrode shield may include an inner electrode shield having a second voltage, and an outer electrode shield having a third voltage.

The present disclosure presents infant soothing devices which provide timed, color, and intensity controlled light and sound projections to assist in sleep therapy. The devices may be part of a smart nursery which has a number of electronically connected devices which communicate with a central electronic application to gather information and provide operation instructions to the devices. The smart nursery may be connected to a larger network to provide feedback and controllability outside of the nursery.