Apparatuses and methods for treating neurological and/or neuropsychiatric disorders are by application of thermal energy to the patient's forehead region, for example, by maintaining a target temperature or temperature range to the forehead of a patient for a time period. In particular, described herein are regional brain cooling mechanisms to treat neuropsychiatric disorders such as depression, anxiety, and autism.

The invention relates to a patient interface comprising a plenum chamber, a seal-forming structure, and a positioning and stabilizing structure, as well as the method of operating the patient interface. The patient's interface is configured to leave a patient's mouth uncovered or if the seal-forming structure is configured to seal around a patient's nose and mouth, the patient interface is configured to allow the patient to breath from the ambient in an absence of the flow of pressurized. The positioning and stabilizing structure includes headgear, and the seal-forming structure and at least a portion of the headgear is formed from a one piece construction of textile material. In another embodiment, the seal-forming structure and/or the positioning and stabilizing structure includes an adaptive portion that adjusts based on usage conditions. In another embodiment, the positioning and stabilizing structure, the seal-forming structure and/or the plenum chamber includes and/or is formed of a textile material, and the textile material includes at least one magnetic thread constructed of magnetic material to provide a magnetic interaction between a first part of the patient interface and a second part of the patient interface. In another embodiment, a stiffener is coupled to the plenum chamber, the seal-forming structure, and/or the positioning and stabilizing structure. In another embodiment, at least one of the plenum chamber and the seal-forming structure includes a textile material; and wherein the textile material includes a surface structure that limits adhesion of debris. A UV cleaning receptacle of the patient interface is also disclosed.

Methods, systems and devices for reducing anxiety, including increasing relaxation and/or calm. In some variations these methods may include reducing anxiety, increase relaxation and/or calm by non-invasive temperature regulation of the frontal cortex prior to and/or during sleep. The subject may have an anxiety disorder, or may not have a diagnosed anxiety disorder.

A wearable device 100 for managing alcohol-driven violence is disclosed. The device 100 comprises a capsule C1 adapted to sense sweat of wearer and detect a level of alcohol in the sweat, a capsule C3 adapted to convert a data detected by the capsule C1 to generate signal activating a capsule C4, a capsule C2 adapted to provide power to the capsule C3, and a capsule C5 adapted to detect a muscle activity of the wearer, wherein the capsule C4 is adapted to inject a drug into the body of the wearer, when activated, and wherein the capsule C5 alerts authorities when no muscle activity is detected.

A U sleep weighted pillow promotes healthy sleep essential oils is presented. The U sleep weighted pillow provides comfort to a head, to an upper portion of the face, for body aches and pains. The U sleep weighted pillow provides a warming or a cooling to a desired body part while a person is laying down, sitting, etc. The U sleep weighted pillow further has custom weighting and firmness of the U sleep weighted pillow by the person. The U sleep weighted pillow helps restore movement from injured tissue, reduces joint stiffness, muscle spasms, sprains, strains, whiplash, pain relief, ease pain from both acute and chronic injuries, arthritis, promotes blood circulation and helps to relax muscle.

Devices for delivering a controlled concentration of an agent are provided. The device includes a reservoir for the agent and a flow control portion operably connected to the reservoir. The device also includes a valve for releasing the agent from the flow control portion and a pump for flowing air to mix with the agent released by the valve and for flowing the agent and air mixture out of the device. Methods of delivering a vaporized agent to a subject are also provided. The methods include storing a liquid agent in a reservoir of a device and flowing the agent into a flow control chamber to change the agent to a gas. The methods also include mixing the agent in gas form with air and flowing the agent and air mixture out of the device to be delivered to a subject.

A tank for accumulating oxygen enriched air from an oxygen concentration device is disclosed. The oxygen concentration device includes a canister including a nitrogen-adsorbent material. A compressor is coupled to the canister. The compressor compresses air for the canister to produce oxygen enriched air in a swing adsorption process. The tank includes a closed container for collecting oxygen enriched air produced in the canister. An inlet is coupled to the container. An outlet in the container allows a patient to inhale the collected oxygen enriched air. An adsorbent material within the container adsorbs oxygen enriched air added to the tank from the canister.

A method of forming an implant in the tissue can include: providing an injectable composition having a neat liquid carrier, wherein the neat liquid carrier is substantially liquid at room temperature and/or about body temperature; and injecting the neat liquid solution into the tissue at the rate of 10-12000 injections per minute and/or at an amount of 1.0E-02 ml to 1.0E-16 ml per needle per injection. The neat liquid carrier can be polymeric or non-polymeric. The neat liquid carrier can be biodegradable. The neat liquid carrier can include a viscosity-modifying agent. The injecting can form an implant with area greater than or equal to 5 mm.sup.2. The neat liquid carrier can be injected at a depth of 10 microns to 5 mm. The neat liquid solution can include a drug or other agent.

On-demand, hand-held vaporizer that operates primarily by convection. The vaporizer is configured to permit very rapid (e.g., within a few seconds) heating of air drawn through an oven chamber to a predetermined or selectable vaporizing temperature to vaporize a material (e.g., loose leaf plant material, etc.) that is held in the oven chamber. The vaporizer provides efficient transfer of air being heated as well as rapid delivery of vaporizable material to a user.

An infusion pump system is disclosed. The infusion pump system includes an infusion pump and a controller device in wireless communication with the infusion pump, wherein the controller including instructions for controlling the infusion pump, wherein the instructions may be synchronized with a secure web portal.