A dialysis system (e.g., a hemodialysis (HD) system) can be designed to operate in alternative environments, such as disaster relief settings or underdeveloped regions. The dialysis system can include a solar panel for generating electricity to power the dialysis machine and an atmospheric water generator for extracting water from ambient air. The extracted water can be used to generate dialysate and saline on-site. One or more of the components of the dialysis machine can be discrete components that are configured to facilitate fast shipping and simple on-site assembly (e.g., at a remote location). In some implementations, the discrete components may be configured to be attached to an existing dialysis system (e.g., a dialysis system designed for operation in a traditional environment) to permit the dialysis system to operate in an alternative environment.

Implementations of the present disclosure are directed to conserving energy of an injection device that includes an energy source configured to power an electronic component, a priming component configured to generate a trigger, a reactant configured to generate an instantiation signal in response to the trigger, and a sensor configured to detect and process the instantiation signal and generate an activation signal to activate the energy source.

An automatic injection device with flow regulation. The automatic injection device has an insertion needle configured to be inserted into a patient and a drug container which contains a pharmaceutical product and includes a plunger. The automatic injection device also has a fluid path which fluidly connects the drug container to the patient via an insertion needle, a potential energy source, and a regulator configured to restrict release of potential energy and restrict linear movement of the plunger and the pharmaceutical product into the fluid path at a proscribed pace. The regulator includes a clock escapement mechanism and a wire and pulley system including a wire coupled to at least one pulley. The potential energy source may be a spring that surrounds the drug container and may be directly coupled to the plunger and the wire such that movement of the spring and the wire is restricted over time.

An automatic injection device with flow regulation is disclosed. The automatic injection device has an insertion needle configured to be inserted into a patient and a drug container which contains a pharmaceutical product and includes a plunger. The automatic injection device also has a fluid path which fluidly connects the drug container to the patient via the insertion needle, a potential energy source, and a regulator configured to restrict release of potential energy and restrict linear movement of the plunger and the pharmaceutical product into the fluid path at a proscribed pace. The regulator includes a clock escapement mechanism. The potential energy source may be a spring that surrounds the drug container and may be magnetically coupled to the plunger. The clock escapement mechanism is configured to control the spring at a regulated rate over a time interval using a gearbox and a rotational-to-linear translator comprising a rack and a pinion.

The present invention relates to the art of automatic regulation of pulmonary devices for imitating, assisting and/or enforcing the breathing process by converting Bag-Valve-Mask (BVM) or a similar device to enhance both phases of breathing: inhalation and exhalation while applying a variable pressure during the breathing process. It also replaces a mechanical chest compression to the sternum area for automatic pneumatic compression, and it could be complimented with the use of a Tens unit, can be used for extended period of time with a high level of reliability, simplicity, efficacy and low cost. The unique filtration system's goal in this invention is safety of the treating patient as well as assisting personnel. This portable and light device is recommended to be used as a resuscitator for the patients with mild to extremely suppressed or without respiratory drive. The source of power can be electrical, battery operated, manual or a combination thereof.

An automatic injection device with flow regulation. The automatic injection device has an insertion needle configured to be inserted into a patient and a drug container which contains a pharmaceutical product and includes a plunger. The automatic injection device also has a fluid path which fluidly connects the drug container to the patient via an insertion device, a potential energy source, and a regulator configured to restrict release of potential energy and restrict linear movement of the plunger and pharmaceutical product into the fluid path at a proscribed pace. The regulator includes a clock escapement mechanism and a wire and pulley system including a wire coupled to at least one pulley. The potential energy source may be a spring that surrounds the drug container and may be directly coupled to the plunger and the wire such that movement of the spring and the wire is restricted over time.

The invention relates to an apparatus for exchanging material between blood and a gas/gas mixture, comprising a chamber (1) through which blood can flow and in which a plurality of material-permeable fiber tubes is provided, the gas/gas mixture being flowable through the fiber tubes, blood being flowable around the fiber tubes. At least one deformable element (9) is provided in the chamber (1) in addition to the fiber tubes, through which the gas/gas mixture can flow, this deformable element being deformable and restorable, in particular compressible out of a relaxed shape and restorable to a relaxed shape by pressure fluctuations acting on the at least one element (9) externally, in particular pressure fluctuations transmitted by the blood in the chamber (1).

An automatic injection device with flow regulation is disclosed. The automatic injection device has an insertion needle configured to be inserted into a patient and a drug container which contains a pharmaceutical product and includes a plunger. The automatic injection needle also has a fluid path which fluidly connects the drug container to the patient via an insertion device, a potential energy source, and a regulator configured to restrict release of potential energy and restrict linear movement of the plunger and the pharmaceutical product into the fluid path at a proscribed pace. The regulator includes a clock escapement mechanism. The potential energy source may be a spring that surrounds the drug container and may be magnetically coupled to the plunger. The clock escapement mechanism is configured to control the spring at a regulated rate over a time interval using a gearbox and rotational-to-linear translator comprising a rack and a pinion.

Adherence monitors are disclosed, incorporating cap removal sensors together with a determined time period in order to determine that a dose of medicament has been dispensed. In another form, cap removal data is combined with acoustic data to determine that a dose of medicament has been dispensed. Several specific structural arrangements are also disclosed.

A device for infusing a medicament into a patient includes a disposable component having a collapsible reservoir for holding the medicament, a cannula, and an elastomeric tube connected in fluid communication between the reservoir and the cannula. A manipulator is mounted on a chassis for engagement with the elastomeric tube. The manipulator includes a piston and respective pinchers upstream and downstream from the piston for a close/open open/close changeover operation. In concert therewith, the piston cyclically advances and withdraws relative to a platen to thereby alternatingly dilate/constrict the tube section. When the upstream pincher is open, the piston withdraws to create a low fluid pressure, p.sub.Lo, in the tube section to draw medicament into the tube. Alternately, when the downstream pincher is open, the piston is advanced to create a high fluid pressure, p.sub.Hi, on the tube to infuse medicament into the patient.