Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat. Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.

A device for irrigation of an oral cavity in a patient includes a suction element configured to be disposed in the oral cavity and configured to suction a fluid out of the oral cavity. The suction element also has one or more irrigation outlets configured to irrigate the oral cavity with the fluid. A suction line is fluidly coupled with the suction element and is configured to be fluidly coupled with a vacuum source. An irrigation line is fluidly coupled with the one or more irrigation outlets and is fluidly coupled with a source of the fluid.

An optimization methodology is employed to match vibratory inhaler devices having certain characteristics to the particular anatomical and acoustic properties of a patient's vocal tract, in order to achieve the most effective dispersion of a dry powder medicament using inspiratory effort of a user of the inhaler. In embodiments, optimization involves employing one or more measurements of acoustic frequency spectrum properties as well as one or more anatomical/geometric measurements of the structures comprising the particular patient's mouth, pharynx, and upper respiratory tract and matching a vibratory inhalation device that corresponds thereto.

Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat.

A device for insertion into an airway of a subject, the device including: an arm defining a distal end and a proximal end, the arm including: an elongate handle portion at the proximal end, the handle portion extending substantially towards the distal end, and an offset portion located between the distal end and the handle portion, the offset portion being offset dorsally relative to the handle portion and the distal end; and a tip at the distal end of the arm, wherein the arm is configured to allow a user to hold the handle portion outside of a mouth of the subject and move the handle portion to move the tip through the mouth and pharynx of the subject to thereby position the tip proximate to a larynx of the subject.

Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodeling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices (e.g., guide catheters, tubes, guidewires, elongate probes, other elongate members) may be used to facilitate insertion of working devices (e.g. catheters e.g. balloon catheters, guidewires, tissue cutting or remodeling devices, devices for implanting elements like stents, electrosurgical devices, energy emitting devices, devices for delivering diagnostic or therapeutic agents, substance delivery implants, scopes etc.) into the paranasal sinuses or other structures in the ear, nose or throat, Specific devices (e.g., tubular guides, guidewires, balloon catheters, tubular sheaths) are provided as are methods for manufacturing and using such devices to treat disorders of the ear, nose or throat.

Oral gas catheters and methods of inducing gas in a patient orally. The oral gas catheter includes one or more delivery cannulas configured to be inserted into the patient's mouth with a distal end of the delivery cannula disposed adjacent the patient's laryngeal inlet, and a clip disposed on the delivery cannula. The clip is configured to secure the delivery cannula to a tooth of the patient. The oral gas catheter may have two such delivery cannulas and clips with the delivery cannulas coupled together by a coupler. The delivery cannulas are placed in an operative position in a patient's mouth and secured in the operative position by releasably securing the clips to the patient's teeth. The oral gas catheter makes it possible to bypass the nasal cavity and deliver oxygen or other gas directly adjacent the laryngeal entrance and into an anatomical dead space of the airway.

A device and a method for creating and/or maintaining an obstruction free upper respiratory passages. The device is configured to fit under the chin of a subject adjacent to the subject's neck at an external location corresponding approximately with the subject's soft tissue associated with the neck's anterior triangle. The device is capable of exerting negative pressure on the surface of a subject's neck, displacing the soft tissue forward and enlarging the airway.

An airway assist device and methods of making and using an airway assist device to assist in opening an airway or removing fluid or material obstructing an airway of a subject.

Systems and methods are provided for aerosolizing and delivering therapeutic substances in an electronic aerosol delivery device with airflow regulation. Calibrated airflow resistance settings enable adjustment and control of flow velocity and or flow volume of air, aerosolized air, and or entrained aerosol particles, through the device, for optimal aerosol delivery among diverse conditions and applications.