A61M2210/1039

DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS
20230050453 · 2023-02-16 ·

Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

METHODS AND APPARATUSES FOR DELIVERY OF AN AGENT TO THE LUNGS AND NASAL PASSAGES
20230052806 · 2023-02-16 ·

Methods and apparatuses (e.g., systems, devices, etc.) for delivering a nebulized drug agent in the nasal passages concurrent with the lungs.

Contrast imaging agent with dissolved gas-evolving fluid
11576985 · 2023-02-14 · ·

A diagnostic contrast composition includes a carrier fluid and a non-decaying gas-evolving fluid incorporated in the carrier fluid. The gas-evolving fluid has a vapor pressure sufficient to evolve the gas from a circulatory system within a lung of a patient. The gas-evolving fluid is a composition containing a sufficient quantity of atoms with an atomic number higher than 8 to provide an increased absorption sufficient to increase a Hounsfield Unit measurement in an image in a CT imaging system. The gas-evolving fluid is selected from the group consisting of xenon gas, krypton gas, sulfur hexafluoride, a perfluorocarbon, a brominated perfluorocarbon, and combinations thereof. The carrier fluid is selected from the group consisting of water, saline, saline comprising one or more blood proteins, and saline comprising dissolved lipids.

Chest valve for treating pneumothorax
11577011 · 2023-02-14 ·

A chest valve including: a housing including an inlet configured to connect to a chest tube, an outlet and a fluid passage from the inlet to the outlet; and a one-way valve within the housing and included in the flow passage, wherein the one-way valve includes: (i) a first tubular strip wherein having an internal air passage and a first layer defining the air passage, wherein the first layer has a first thickness and the internal air passage of the first tubular strip is included in fluid passage of the housing; and (ii) a second tubular strip wherein having a second layer with a second thickness with a second thickness greater than the first thickness, wherein an outer surface of the second tubular strip is adjacent and overlaps an outer surface of the first tubular strip.

Coaxial breathing circuit systems having a lung pressure measurement port and closed system water trap which can be drained with an enjector

The invention relates to providing novel functions to the coaxial breathing circuits which at present do not comprise water traps, by adding a closed system water trap designed to have an inkwell shape and a lung pressure measurement port to said circuits wherein the fluid collected in the bottle section can be discharged without having to open the bottle by means of a drainage luer port located at the base of the bottle and a needleless apparatus that has been inserted into the port, and an injector.

Apparatus, system and method for performing a bronchoscopy
11690507 · 2023-07-04 · ·

A system and method for performing a bronchoscopy. The system may include a bronchoscope, a multi-fluid conduit apparatus, and a switching apparatus. The bronchoscope may include an insertion tube having a distal end, a control section, and a working channel. The multi-fluid conduit apparatus may include a first conduit section operably coupled to a vacuum source, a second conduit section operably coupled to an oxygen source, and a third conduit section operably coupled to the working channel, each of the first and second conduit sections being fluidly coupled to the third conduit section. The switching apparatus may include a valve apparatus operably coupled to each of the first and second conduit sections and an actuator apparatus operably coupled to the valve apparatus. The actuator apparatus may alter the valve apparatus between: (1) a suction supply state; and (2) an oxygen supply state.

DEVICES, SYSTEMS, AND METHODS FOR ASSESSING LUNG CHARACTERISTICS VIA REGIONAL IMPEDANCE AND PATIENT POSITIONING
20220378314 · 2022-12-01 ·

Methods and systems for assessing characteristics of a lung of a patient. A method includes, during an applied positive end expiratory pressure, identifying a first position of a patient, acquiring first impedance data representative of at least a region of patient's lung when the patient is in the first position, during the applied positive end expiratory pressure, identifying a second different position of a patient, acquiring second impedance data representative of at least the region of patient's lung when the patient is in the second position, comparing the first impedance data with the second impedance data, and determining whether the applied positive end expiratory pressure is sufficient to effectuate recruitment.

Drug-coated balloon catheters for body lumens

Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

CSF DIAGNOSTICS PLATFORM

The present disclosure generally relates to a system for flowing a fluid, e.g., CSF, from a body of a patient for sampling and analysis. In some embodiments, the system can include a diagnostic module having one or more conduits for flowing fluid therethrough. The flow of the fluid through the valves can be regulated using a control board that changes an orientation of valves disposed in the conduits between a dead-end orientation and a flow-through orientation to sample and/or analyze the fluid from the system. In some embodiments, the fluid can be recirculated into the system through one or more of the valves, with sampling and recirculating occurring substantially simultaneously.

BREATHING LUNG DEVICE
20220339379 · 2022-10-27 ·

A device for placing a lung in a variety of different inflation states using positive air pressure. An exemplary device includes a housing and an air supply component. The housing includes a platform receives at least one of a synthetic lung or a real lung. The platform is at the same air pressure as a surrounding environment. The air supply component is located within the one or more internal cavities of the housing. The air supply component inflates the synthetic lung or the real lung with positive pressure.