Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

A unisex urine collection assembly for use by either sex in a non-ambulatory setting includes a tube, which has a cutout positioned in a top face thereof and extending from proximate to a midpoint toward a first end thereof. A second end of the tube is closed. A connector engaged to the first end of the tube can engage a conduit extending from a suctioning unit. Each of a pair of pads is engaged to the tube and extends from a respective opposed edge of the cutout thereinto so that the pads defines a slot. The pads are resiliently flexible and can sealably engage skin of the user. The pads can be positioned between labia of a female user or to bracket a penis inserted into the slot by a male user. Urine expelled by the user is suctioned from the tube into a reservoir.

The present invention is pursuant to the fields of Pharmacy and Medicine. More specifically, the invention provides an intraurethral dosage form of liquid or gel medication for men or women. In one embodiment, an applicator provides advantages in its use, facilitating the application of pharmaceutical compositions directly into the urethral channel and providing fast local effect without substantial risk. The invention provides a dosage form and route of administration for several medications, being particularly useful for the application of anti-inflammatory and/or anesthetic medications, for the treatment of female cystitis, for modulating female genital sensitivity and/or for modulating the erectile function in man, being an advantageous dosage form alternative to the oral or injectable administration of medications or even the intraurethral administration of pills.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

A urinary catheter may include a catheter shaft and a connector coupled with the proximal end of the catheter shaft. The connector may have a first arm ending in a fluid outlet configured to allow urine to flow out of the urinary catheter and a second arm with an aperture and ending in an inflation inlet used for introducing inflation fluid into the urinary catheter. The catheter may further include a primary lumen, an inflation lumen, a retention balloon mounted to the catheter shaft proximal to a fluid inlet and over a distal filling hole, and a pilot balloon mounted on the second arm of the connector over the aperture. The pilot balloon inflates at an inflation pressure that is higher than the inflation pressure of the retention balloon and lower than a predetermined pressure threshold.

A closed-system urinary catheter with a low viscosity gel lubrication is disclosed. The system has an uncoated catheter, but a hydrophilic coated catheter could be used. The low viscosity lubricating gel within the sachet uniformly coats the catheter when the sachet is ruptured just prior to use. A low viscosity lubrication gel could alternatively be place in the area inside the sheath and external to the catheter. Therefore, the variability that occurs with a hydrophilic catheter or the areas of a non-lubricated catheter with the higher viscosity gel catheters is avoided.

Hydration mediums, assemblies containing hydration mediums and methods of making the same.

A urinary catheter conveying device includes a sleeve member, a conveying assembly and a controller. The sleeve member is for sleeving onto a glans of a penis and has a guiding hole to be registered with an external urethral orifice of the glans. The conveying assembly includes a casing removably mounted to the sleeve member, and a conveying mechanism for advancing the urinary catheter to the guiding hole such that the urinary catheter is inserted into the external urethral orifice. The controller controls the conveying mechanism to advance the urinary catheter to the guiding hole. A urinary catheterization system and a method of using the urinary catheterization system are also disclosed.

Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

A urinary-catheter package (100) includes a container (120) including a urinary catheter (110) and a lubricant (140). The urinary catheter includes a catheter tube (112) and a drainage lumen extending through the urinary catheter, the drainage lumen fluidly coupling a plurality of eyelets in a distal-end portion of the catheter tube with an opening in a proximal end of the urinary catheter. The container includes a catheter section (122), a lubricant section (124) in a distal-end portion of the container, and a separator (126) between the catheter section and the lubricant section. The catheter section is configured to hold the urinary catheter, and the lubricant section is configured to hold the lubricant. The separator is configured to separate the lubricant in the lubricant section from the urinary catheter in the catheter section until the separator is broken by a user.