Systems and methods are provided to combine multiple stimulation modalities to significantly increase the effectiveness of non-invasive stimulation. Multiple sensor and stimulation devices and modalities can be combined into a single, compact unit that minimizes the need for additional sensors or stimulation devices. The system features several subunits, referred to as sensory and stimulation devices (SSD), that are integrated into a headphone setup. The system is controlled by a centralized controller that communicates with all of the SSDs and with an external computer system that delivers learning material synchronized with the delivery of stimulations and the collection of user responses based on physiological signals.

A respiratory assistance system can provide high flow therapy to patients. The respiratory assistance system can include a patient interface that can deliver a gas flow to a patient and a gas source that can drive the gas flow towards the patient interface at an operating flow rate. The system can include a controller for controlling the operating flow rate of the gas. The controller can apply multiple test flow rate values in a range as the operating flow rate. For each of the test flow rate values, the controller can measure a patient parameter. The controller can determine a new flow rate value based on the measured patient parameters. Patient parameters can include respiration rate, work of breathing, or any other parameters related to the respiratory circuit.

The invention relates to medicine, The technical result of the present invention is to increase the efficiency of treatment of the respiratory system pathologies. The system includes a communication unit connected to a ventilator, a human-machine interface unit, a data processing, storage and management unit, an algorithmic unit, a pulse generation unit, a unit of electromyography electrodes and a stimulation.

Disclosed are methods and medical device systems for automated delivery of therapies for pain and determination of need for and safety of treatment. In one embodiment, such a medical device system may comprise a sensor configured to sense at least one body signal from a patient; and a medical device configured to receive a first sensed body signal from the sensor; determine a patient pain index based at least in part on said first sensed body signal; determine whether said patient pain index is above at least a first pain index threshold; determine a safety index based at least in part on a second sensed body signal; select a pain treatment regimen based on at least one of said safety index and or a determination that said pain index is above said first pain index threshold; and deliver said pain treatment regimen.

An audio system adapted to provide an auditory stimulation for inducing neural oscillations in a user during sleep.

A device is described for delivering a therapeutic vibration to a body. The device may include at least two motors in a housing with unbalanced masses coupled to their axles, such that vibration of the masses causes the two motors and housing to vibrate at a beat frequency 80. The motors and housing may be coupled to the body via a platform which places the motors and housings at or near a resonant structure in the body, creating a coupled oscillation between the platform and the body. The vibration may be based on the input signal, such that the system applies the vibration based on the input signal to the user, wherein the signal may be an audio or video signal. The system may be configured to measure and manipulate the flow of cerebral spinal fluid.

A device is described for delivering a therapeutic vibration to a body. The device may include at least two motors in a housing with unbalanced masses coupled to their axles, such that vibration of the masses causes the two motors and housing to vibrate at a beat frequency 80. The motors and housing may be coupled to the body via a platform which places the motors and housings at or near a resonant structure in the body, creating a coupled oscillation between the platform and the body. The vibration may be based on the input signal, such that the system applies the vibration based on the input signal to the user, wherein the signal may be an audio or video signal. The system may be configured to measure and manipulate the flow of cerebral spinal fluid.

A system for carbon dioxide (CO2) removal from a circulatory system of a patient includes a medical device providing extracorporeal lung assist (ECLA) treatment to the patient through extracorporeal removal of CO2 from the patient's blood; at least one control unit controlling the operation of the medical device so as to control a degree of CO2 removal obtained by the ECLA treatment; and a bioelectric sensor detecting a bioelectric signal indicative of the patient's efforts to breathe. The at least one control unit is configured to control the operation of the medical device based on the detected bioelectric signal.

An apparatus and method use a catheter for specific and discriminate treatment of central nervous system disease. With the catheter, selective hypothermia to the brain and/or the spinal cord for injury protection can be achieved without the need for systemic cooling. The catheter is also capable of draining excess cerebrospinal fluid.

A method of determining a duration of safe apnoea. Information is obtained relating to a respiratory indicator, which can include information relating to a potential respiratory equilibrium, and a duration of safe apnoea is determined from the obtained information.