Apparatuses and methods for treating neurological and/or neuropsychiatric disorders are by application of thermal energy to the patient's forehead region, for example, by maintaining a target temperature or temperature range to the forehead of a patient for a time period. In particular, described herein are regional brain cooling mechanisms to treat neuropsychiatric disorders such as depression, anxiety, and autism.

Apparatuses and methods for treating neurological and/or neuropsychiatric disorders are by application of thermal energy to the patient's forehead region, for example, by maintaining a target temperature or temperature range to the forehead of a patient for a time period. In particular, described herein are regional brain cooling mechanisms to treat neuropsychiatric disorders such as depression, anxiety, and autism.

An aerosol provision device includes: a power source and control circuitry. The control circuitry is configured to cause the power source to supply electrical current in accordance with a set duty cycle to an aerosol generator so as to maintain a substantially constant average power, wherein the duty cycle is set dependent on the temperature of the aerosol generator; and wherein the control circuitry is configured to determine a voltage supplied by the power source.

A sensing system for sensing a potential complication at a venous catheter site. The system includes a sensor module for attachment at the site of the catheter. The sensor module includes a pressure sensor configured to generate pressure data representing measured pressure at the site of the catheter; a temperature sensor configured to generate temperature data representing measured temperature at the site of the catheter; and two pairs of bio impedance electrodes that generate bioelectrical signals representing bioelectrical activity at the site of venous catheter and a transmitter for transmitting the pressure, temperature data and bio impedance data. The system also includes a computing device configured to receive the response signal that includes the generated pressure, temperature and bio impedance data; and transmit the pressure temperature and bio impedance data to a user device for comparing the generated pressure temperature bio impedance data to threshold values indicative of intravenous complications.

A system and method for providing sensory relief from distractibility, inattention, anxiety, fatigue, and/or sensory issues to a user in need. The user can be autistic/neurodiverse, or neurotypical. The system can be configured to connect to a datastore storing one or more sensory thresholds specific to a user of a wearable device of the system, the sensory thresholds selected from auditory, visual or physiological sensory thresholds; record, using one or more sensors of the wearable device, a sensory input stimulus to the user; compare the sensory input stimulus with the sensory thresholds to determine an intervention to be provided to the user, the intervention configured to provide the user relief from distractibility, inattention, anxiety, fatigue, or sensory issues; and provide the intervention to the user, the intervention comprising filtering, in real-time, an audio signal presented to the user or an optical signal presented to the user.

A system and method for providing sensory relief from distractibility, inattention, anxiety, fatigue, and/or sensory issues to a user in need. The user can be autistic/neurodiverse, or neurotypical. The system can be configured to connect to a datastore storing one or more sensory thresholds specific to a user of a wearable device of the system, the sensory thresholds selected from auditory, visual or physiological sensory thresholds; record, using one or more sensors of the wearable device, a sensory input stimulus to the user; compare the sensory input stimulus with the sensory thresholds to determine an intervention to be provided to the user, the intervention configured to provide the user relief from distractibility, inattention, anxiety, fatigue, or sensory issues; and provide the intervention to the user, the intervention comprising filtering, in real-time, an audio signal presented to the user or an optical signal presented to the user.

Methods, systems and devices for reducing anxiety, including increasing relaxation and/or calm. In some variations these methods may include reducing anxiety, increase relaxation and/or calm by non-invasive temperature regulation of the frontal cortex prior to and/or during sleep. The subject may have an anxiety disorder, or may not have a diagnosed anxiety disorder.

A prosthetic device includes a flexible interface configured to conform to a residual limb of a user, a prosthetic socket including an outer shell more rigid than the flexible interface and positioned external to at least a portion of the flexible interface, and one or more vibrational devices placed in connection with the flexible interface to impart vibration to the residual limb.

A prosthetic device includes a flexible interface configured to conform to a residual limb of a user, a prosthetic socket including an outer shell more rigid than the flexible interface and positioned external to at least a portion of the flexible interface, and one or more vibrational devices placed in connection with the flexible interface to impart vibration to the residual limb.

Systems and methods are provided for identifying a therapeutic VR activity or exercise for a subject/patient based on the subject's impairments, dynamically adjusting a VR activity for a patient, and identifying potential impairments based on a patient's performance in a VR activity. Patients may each have various physical, neurological, cognitive, and/or sensory impairments to be treated. Not all therapeutic activities may be appropriate for some patients and their impairments. A VR therapeutic activity platform may increase patient engagement and challenge patients at more appropriate times by better matching activities corresponding to a patient's impairments and dynamically adjusting each VR activity based on performance to offer a challenging and rewarding therapeutic experience.