A catheter includes: a body comprising a body side wall, a proximal end and a distal end; a septum extending from the proximal end to the distal end; a first lumen and a second lumen separated by the septum, each lumen forming a mouth at the distal end; first and second slots formed in a portion of the body side wall at the distal end and in fluid communication with the first and second lumens respectively. The first and second slots extend linearly along a direction parallel to a longitudinal axis of the body. The distal end of the body and the septum terminate in a plane perpendicular to the longitudinal axis. The distal end of the body has a substantially round cross section, while the first and second lumens each have a substantially D-shaped cross-section at the distal end. The two slots each have a width that is between 30% and 60% of a longer dimension of the D-shaped cross-section of a corresponding lumen.

A system and method for delivering a medicament including a catheter configured for implantation in different target tissue sites, extending from a proximal end to a distal end, and having a sidewall which defines an internal lumen. The distal end has one or more apertures in the sidewall for the release of the medicament into the target tissue site; the system also comprises a medicament reservoir fluidly communicable with the internal lumen of each catheter, an adhesive member configured to adhere to the skin of the patient around the exit wound and having an opening therein to allow the catheters to pass through the adhesive member and a retaining member configured to be overlaid on the adhesive member and comprising a guide surface configured to receive a length of the two or more catheters and a plurality of retaining portions to retain the catheters against the guide surface.

A catheter device having a distal tube portion having a longitudinal axis and a tube wall comprising at least one side port; and a guide tip mounted on the distal tube portion, the guide tip defining: a unitary body having an outer wall, and a plurality of indentations in the outer wall, wherein the indentations are oriented substantially parallel to the longitudinal axis, and wherein each indentation extends from a distal-most end of the guide tip to a proximal region of the guide tip.

Systems and methods for positioning a wire for advancement through a vessel wall, and advancing it through one or more vessel walls, generally include a delivery catheter and an alignment catheter or a receiving catheter, and a guidewire. In some variations, the systems and methods may be used to bypass an occlusion or other barrier that may prevent advancement of a wire or tools through an endoluminal space. In these variations, the systems and methods include a delivery catheter, a bypass catheter, a receiving catheter, and a guidewire. The delivery and receiving catheters each generally include a side aperture, a deflection surface, and an alignment element, and the bypass catheter generally includes two side apertures, two deflectors, and two alignment elements. In some variations, the systems and methods may assist in treatment of a patient suffering from critical limb ischemia.

A delivery system can be provided with an ability to change its configurations to achieve both access to target anatomy and treatment thereof. Such treatments can include directing interventional devices around an occlusion. By providing different functionality at different stages, the need to exchange and replace tools at different stages can be reduced or eliminated. Accordingly, such operations can be completed more rapidly, efficiently, and safely.

Methods and devices are disclosed for passing Chronic Total Occlusion (CTO) from subintimal location and re-entry into a true-lumen of the patient using transient fenestration approach. The transient fenestration is induced by balloon dilatation within the CTO, and a guidewire quickly trails into a true lumen.

The present invention discloses a catheter system, comprising: a catheter head having a lumen, a proximal end and a distal end, and an opening positioned at a bottom of the distal end; and a rotatable inner tube having a lumen positioned in the lumen and at a proximal end of the catheter head, the inner tube including a front end having an arcuate opening; wherein the rotatable inner tube can be rotated so that the arcuate opening thereon can be made to engage or disengage with the opening at the bottom of the distal end of the catheter head. The invention also provides a catheter system and method for re-entry of a vascular false lumen into a true lumen in a quick, accurate and low-risk way. The catheter system for re-entry of a vascular false lumen into a true lumen in a quick, accurate and low-risk way effectively solve the problems of difficult operation, inaccurate positioning, long operation time and easiness to cause acute occlusion and internal hemorrhage of the branch vessel when the guidewire is re-entering the true lumen in the prior art.

An external end device has a casing (4), including a base (5), in which a distal opening (12) is formed which receives a funnel-shaped septum (14) having a tube trunk (140). Inside the tube trunk (140) the catheter (3) is connected to the distal section (16) of the fitting (15). A tubular coating (2) has a proximal end adapted to be grafted onto the tube trunk (140) and a distal end coaxially adhering to the catheter (3). A pair of bands (90, 91) of tissue-ingrowth material is fixed on the tubular coating (2), and an anchor ring (92), equipped with anchoring means, is sandwiched between the bands (90, 91).

A catheter may include a catheter body having a tubular shape, a cuff encircling the catheter body, and a wire mesh attached to and encircling the catheter body. The cuff may be configured for facilitating fibrous tissue growth. The wire mesh may be configured for radially expanding away from the catheter body.

A method of manufacturing a catheter assembly including a proximal catheter assembly portion and a distal catheter assembly portion. The method of manufacturing comprises forming the proximal catheter assembly portion, creating a distal catheter assembly portion, and applying a polymeric coating to at least one of the proximal catheter assembly portion and the distal catheter assembly portion. The proximal catheter assembly portion can include a catheter hub and at least one cannula, the catheter hub including at least one fluid passageway in communication with a lumen of the at least one cannula. The distal catheter assembly portion can include a catheter tube defining at least one lumen designed to receive the at least one cannula. The polymeric coating is configured to provide a seal between the at least one cannula and the catheter tube when the proximal catheter assembly portion and the distal catheter assembly portion are connected.