A sterile packaging assembly for transporting interventional devices to a robotic surgery site includes a sterile barrier having a hub support portion and configured to enclose a sterile volume; and at least a first interventional device within the sterile volume. The first interventional device includes a hub and an elongate flexible body. The hub includes at least one magnet and at least one roller configured to roll on the hub support portion of the sterile barrier.

A coil wire and method of using the coil wire to navigate blood vessels are provided. The coil wire is configured to facilitate coaxial catheter advancement over at least a part of the length of the coil wire. Existing catheters utilize the distal tip of a guidewire to select the vessel origins by shaping it (either during fabrication or by the operating physician) in such a way that the tip will point into the desired vessel as the wire is advanced. The coil wire of the present disclosure functions in a unique manner: its distal tip resumes a pre-formed three-dimensional coil configuration as it is expressed from the catheter. This shape catches the flow of moving blood and propels the coil wire forward while unfurling the coil. As the coil wire is advanced, the small outer diameter of the unfurled coil allows it to pass deep into the selected vessel.

A knitted stent and a knitted stent system are disclosed, the knitted stent system comprising the knitted stent, a knitted stent (100) is formed by spirally coiling a knitted wire about an axis in an interlaced manner. The knitted wire includes at least one elastic metal tube (110), each elastic metal tube (110) defining a first lumen and having a wall in which release holes (111) in communication with the first lumen are formed. The first lumen can serve as a drug receptacle. A drug can be filled in the receptacle and released from the release holes (111). In this way, the knitted stent (100) can be used as a base of a drug-loaded stent, thus solving the problem of poor geometric compliance and fatigue resistance arising from the use of conventional drug-loaded stents.

A catheter-based device for determining the radial expansion force required to displace an occlusion in a vessel located in a subject. The device comprises an elongate body defining proximal and distal termini. The body comprises a sheath that encloses a hollow lumen within, which extends along substantially the full length of the body. The proximal terminal region of the body comprises: a user-interfacing hub, the hub comprising a handle for maneuvering the body and configured for handling by an operator; a control interface for controlling the device; and a sensor configured to measure one or more parameters relevant to a force applied to the vessel by the device. The distal terminal region of the body comprises an expandable member movable between a retracted position, in which the expandable member is within the hollow lumen, and a deployed position, in which the expandable member is disposed beyond the distal terminus, and controllable via the control interface to expand radially. The expansion of the expandable member is correlated to a defined radial expansion force value.

A robotically driven interventional device includes an elongate, flexible body, having a proximal end and a distal end; a hub on the proximal end; at least one rotatable roller on a first surface of the hub; and at least one magnet on the first surface of the hub.

A combined system for diagnostic and therapeutic procedures includes a needle extending longitudinally from a proximal end to a distal end and including a lumen extending therethrough, the distal end including a sharp grind for cutting a tissue sample to be collected in the lumen of the needle and a protective sheath sized and shaped to be inserted through the lumen of the needle such that a distal end of the protective sheath extends distally past the distal end of the needle, the protective sheath extending longitudinally from a proximal end to the distal end and including a lumen extending therethrough.

A combined system for diagnostic and therapeutic procedures includes a needle extending longitudinally from a proximal end to a distal end and including a lumen extending therethrough, the distal end including a sharp grind for cutting a tissue sample to be collected in the lumen of the needle and a protective sheath sized and shaped to be inserted through the lumen of the needle such that a distal end of the protective sheath extends distally past the distal end of the needle, the protective sheath extending longitudinally from a proximal end to the distal end and including a lumen extending therethrough.

A catheter insertion device includes a housing, a needle, a guide wire, and a catheter disposed coaxially over the needle. The needle has a proximal end in the housing and a distal end extending from a distal end of the housing in an insertion position. The guide wire has a distal portion disposed in a lumen of the needle in a withdrawn position. The guide wire may include a safety tip having a non-coiled configuration in the withdrawn position and a coiled configuration in an advanced position. The catheter insertion device may include a sliding member attached to the guide wire, wherein movement of the sliding member translates the guide wire from the withdrawn position to the advanced position.

A catheter insertion device includes a housing, a needle, a guide wire, and a catheter disposed coaxially over the needle. The needle has a proximal end in the housing and a distal end extending from a distal end of the housing in an insertion position. The guide wire has a distal portion disposed in a lumen of the needle in a withdrawn position. The guide wire may include a safety tip having a non-coiled configuration in the withdrawn position and a coiled configuration in an advanced position. The catheter insertion device may include a sliding member attached to the guide wire, wherein movement of the sliding member translates the guide wire from the withdrawn position to the advanced position.

Medical guidewire assembly is movable through guidewire introducer positionable proximate to a biological wall located within the body of a patient. Medical guidewire assembly has flexible distal shaft section configured to extend along the guidewire introducer. Medical guidewire assembly has a predetermined spatial geometry once the flexible distal shaft section is removed from guidewire introducer. Medical guidewire assembly also has a piercing stylet device configured to puncture the biological wall in response to placement of guidewire introducer (in use) proximate to the biological wall, and movement of the flexible distal shaft section through the guidewire introducer. The predetermined spatial geometry is configured to prevent physical contact between the piercing stylet device and adjacently positioned tissue of the patient in response to formation of the predetermined spatial geometry.