An external end device has a casing (4), a fitting (15) housed in the casing (4) and having at least one distal part (16) which engages a catheter (3), and two proximal tracts (17, 17), in which a pair of curved pipes (18, 18) are inserted with a distal end (180) thereof. The curved pipes (18, 18) have a proximal end (181), in which a pair of nozzles (190, 190) are inserted. Inside each nozzle (190) there is a cap (20) suitable for hermetically sealing the nozzle (190). A piercing and connecting conduit (24) is adapted to reversibly pierce the cap (20) and to connect the pair of nozzles (190, 190) to the flow lines of the treatment equipment. Also disclosed is a method of connecting the external terminal device to flow lines of a machine.

An adapter for connecting a first connector to a second connector can include a proximal portion configured to linearly engage the first connector with a snap-fit engagement. The adapter can include a distal portion configured to rotationally engage the second connector. Rotation of the adapter relative to the second connector can advance a male luer of the first connector into substantially sealing engagement with a female luer on the second connector. The adapter can be configured to displace a collar on the first connector when coupled to the first connector. The second connector can include a proximal portion that is configured to engage the first connector, such as with a snap-fit engagement.

A fluid pathway connection includes a piercing member, a connection hub, and a sliding pierceable seal, wherein the sliding pierceable seal is configured to move from a first position, where the piercing member is initially retained within a sterile cavity between the connection hub and the sliding pierceable seal, to a second position, where the pierceable seal has been penetrated by the piercing member. A filter may be utilized to enclose the sterile cavity from the outside environment. The fluid pathway connection may further be configured to move to a third position where one or more interconnects and/or one or more corresponding contacts are permitted to transmit a signal to the user. Such fluid pathway connections may be integrated into a drug container having a barrel and a plunger seal. A drug delivery pump includes such integrated fluid pathway connections and drug containers.

A fluid pathway connection includes a piercing member, a connection hub, and a sliding pierceable seal, wherein the sliding pierceable seal is configured to move from a first position, where the piercing member is initially retained within a sterile cavity between the connection hub and the sliding pierceable seal, to a second position, where the pierceable seal has been penetrated by the piercing member. A filter may be utilized to enclose the sterile cavity from the outside environment. The fluid pathway connection may further be configured to move to a third position where one or more interconnects and/or one or more corresponding contacts are permitted to transmit a signal to the user. Such fluid pathway connections may be integrated into a drug container having a barrel and a plunger seal. A drug delivery pump includes such integrated fluid pathway connections and drug containers.

A medical connector of the present invention is characterized in that: when a male connector portion is inserted into a female connector portion, a first locking portion is engaged with the female connector portion to achieve a first locked state as well as a second locked state; when the second locked state is released by operation of a second unlock operating portion and the female connector portion is moved in a disengagement direction with respect to the male connector portion, the locking member is moved in the disengagement direction together with the female connector portion while keeping the first locked state; and when the female connector portion is rotated with respect to the male connector portion, the first locked state is released.

A medical device comprising an implantable subcutaneous access port having a septum penetrable by a needle; the septum having a cavity located between an outer wall and an inner wall, the cavity containing a flowable media comprising a plurality of displaceable particles arranged to move in response to the needle being inserted through the outer wall and into the cavity and reposition around the needle.

A medical device comprising an implantable subcutaneous access port having a septum penetrable by a needle; the septum having a cavity located between an outer wall and an inner wall, the cavity containing a flowable media comprising a plurality of displaceable particles arranged to move in response to the needle being inserted through the outer wall and into the cavity and reposition around the needle.

A female connector that allows connection of a male connector including a lock claw and a channel connection. The female connector includes a cap including a top provided with an opening and a peripheral wall extending from an outer peripheral edge of the top; a housing including a cylindrical wall and an engaging protrusion protruding from an outer peripheral surface of the cylindrical wall to form a lower surface engaged with the lock claw; and a valve including a portion sandwiched between the top and the cylindrical wall and a portion penetrating the valve in up-and-down direction. A boundary is formed between an upper surface of the engaging protrusion and a lower end face of the peripheral wall. The lower end face is smaller than the upper surface in outer diameter. The engaging protrusion has an outer peripheral surface including a portion with a diameter increasing downward from the boundary.

A female connector that allows connection of a male connector including a lock claw and a channel connection. The female connector includes a cap including a top provided with an opening and a peripheral wall extending from an outer peripheral edge of the top; a housing including a cylindrical wall and an engaging protrusion protruding from an outer peripheral surface of the cylindrical wall to form a lower surface engaged with the lock claw; and a valve including a portion sandwiched between the top and the cylindrical wall and a portion penetrating the valve in up-and-down direction. A boundary is formed between an upper surface of the engaging protrusion and a lower end face of the peripheral wall. The lower end face is smaller than the upper surface in outer diameter. The engaging protrusion has an outer peripheral surface including a portion with a diameter increasing downward from the boundary.

A method and apparatus for treating a clot in the blood vessel of a patient, and particularly the treatment of a pulmonary embolism is disclosed. The treatment includes restoring flow through the clot followed by clot removal, either partially or substantially completely. The clot treatment device is expandable into the blood vessel and may contain radial extensions that assist in restoring flow as well as in removing clot material.