Systems, methods, and apparatuses for irrigating a tissue site are described. The system can include a tissue interface and a sealing member configured to be placed over the tissue site to form a sealed space, and a negative-pressure source fluidly coupled to the sealed space. The system includes an irrigation valve having a housing, a piston disposed in the housing, a fluid inlet to fluidly couple a fluid inlet chamber to a fluid source, and a fluid outlet to fluidly couple a fluid outlet chamber to the sealed space. A piston passage extends through the piston and fluidly couples the fluid inlet chamber and the fluid outlet chamber, and a biasing member is coupled to the piston to bias the irrigation valve to a closed position. The negative-pressure source is configured to move the piston between the closed position and an open position to draw fluid to the sealed space.

A dialysis valve includes a tube attached between an artery and a vein which, when elongated, simultaneously narrows in diameter at at least one location. The narrowed portion of the tube decreases the volume and velocity between the arterial and venous side of the patient to prevent damage or intimal hyperplasia on the venous side between dialysis treatments. When the valve is opened for dialysis, an unrestricted blood flow exists between the arterial and venous side, permitting a controlled, open blood flow during dialysis.

A valved nasal cannula adapted to provide a positive pressure in the airway using the breathing of the intended user as a source of positive pressure without the need for an external source of energy and/or compressed air. The cannula is designed so as to be relatively easily insertable and retractable into and from the nasal vestibule portion of the nose of the intended user without requiring manual dexterity.

An arteriovenous graft system is described. The arteriovenous graft system includes an arteriovenous graft that is well suited for use during hemodialysis. In order to minimize or prevent arterial steal, at least one valve device is positioned at the arterial end of the arteriovenous graft. In one embodiment, for instance, the arteriovenous graft system includes a first valve device positioned at the arterial end and a second valve device positioned at the venous end. In one embodiment, the valve devices may include an inflatable balloon that, when inflated, constricts and closes off the arteriovenous graft. If desired, a single actuator can be used to open and close both valve devices.

A self-sealing catheter valve that includes a flexible tubular part having a distal opening and an opposite proximal opening, and a proximal valve part. The proximal valve part has a curved self-sealing flexible diaphragm disposed inside the flexible tubular part and has a base perimeter united with a circumferential wall of the flexible tubular part. The curved self-sealing flexible diaphragm has a concave surface facing towards the proximal opening, and a convex surface facing towards the distal opening, and a flexible diaphragm wall of the curved self-sealing flexible diaphragm has a traverse slit. The self-sealing catheter valve provides an efficient self-closing mechanism for a peripheral catheter assembly and constitutes an efficient barrier against potential contagious spread from the patient to the surrounding environment by blood born disease e.g. HIV, hepatitis and Ebola viruses.

A subcutaneous arteriovenous graft system includes an arteriovenous graft having an arterial end, a venous end opposite to the arterial end and an internal volume between the arterial end and the venous end, and a valve device that can be arranged in an open state, in which fluid flow through the graft is possible and a closed state in which the fluid flow through the arteriovenous graft is blocked. The valve device is constructed to decrease, in the closed state of the valve device, the internal volume of the complete graft to substantially zero.

A pressure relief valve for a reservoir has a main body with a central chamber defining an outer radial seat, a positive-pressure port with an inner radial seat, and a negative-pressure port comprising an internal passage spanning the outer seat. The sealing disk has an anchor body retained in the central chamber and a flexible diaphragm biased against the outer seat. An axial passage in the anchor body couples the central chamber to ambient atmospheric pressure. The sealing ball is biased against the inner seat. When a pressure inside the reservoir exceeds ambient by a positive-pressure threshold, then the sealing ball lifts off the inner radial seat to exhaust a gas through the positive-pressure port. When the pressure inside the reservoir is below ambient by a negative-pressure threshold, then the diaphragm is lifted off the outer seat to intake atmospheric gas into the reservoir.

A system is described herein that can irrigate a tissue site using negative-pressure. The system may include a tissue interface configured to be placed adjacent to the tissue site, and a sealing member configured to be placed over the tissue interface to form a sealed space. The system may also include a negative-pressure source configured to be fluidly coupled to the sealed space and a fluid source. The system may further include an irrigation valve. The irrigation valve can have a fluid inlet configured to be fluidly coupled to the fluid source. The irrigation valve can also have a fluid outlet configured to be fluidly coupled to the sealed space. The irrigation valve may also include a clamp configured to be actuated by the negative-pressure source to regulate fluid flow from the fluid source through the fluid outlet.

Embodiments disclosed herein are directed to a drainage control system including, a tubular body with a tubular body lumen extending from a distal end to a proximal end and a collapsible tube disposed within the tubular body lumen, the collapsible tube including a collapsible tube lumen extending from a distal end to a proximal end of the collapsible tube. The collapsible tube can be attached to the tubular body, such that fluid flow through the tubular body lumen flows through the collapsible tube lumen. The tubular body can include a valve that is actuatable between a first configuration wherein fluid flow is allowed through the tubular body lumen and a second configuration wherein fluid flow is prevented through the tubular body lumen. An airflow source can be coupled to the valve such that pressure from the airflow source actuates the valve.

An arteriovenous graft system is described. The arteriovenous graft system includes an arteriovenous graft that is suited for use during hemodialysis. In order to minimize or prevent arterial steal, at least one valve device is positioned at the arterial end of the arteriovenous graft. In one embodiment, for instance, the arteriovenous graft systems includes a first valve device positioned at the arterial end and a second valve device positioned at the venous end. In one embodiment, the valve devices may include an inflatable balloon that, when inflated, constricts and closes off the arteriovenous graft. If desired, a single actuator can be used to open and close both valve devices.