A pre-filled medical delivery assembly assembled and configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another.

A sealing container is designed to enable a user to adjust the timing of discharging the contents. The sealing container includes: a bag-shaped member for accommodating the contents therein, a sealing film for sealing the bag-shaped member, an opening means so configured that at least a part of which is movable toward the sealing film and is capable of opening the sealing film, an operation unit for performing an operation of moving the opening means, and a discharge means configured to be capable of discharging the contents from the bag-shaped member at a timing different from a timing at which the opening means penetrates the sealing film by operating the operation unit. It is possible for the user to perform only the operation of opening the sealing film by operating the operation unit, so that the user is able to arbitrarily adjust the timing at which the content is discharged from the bag-shaped member of the sealing container.

A single use pre-filled delivery device is disclosed having a deformable container including a side wall having an inside surface defining a chamber for retaining fluid, a clip element, and a locking element. The deformable container further includes a closed proximal end and an open distal end including a male luer tip having a passageway therethrough providing fluid communication with the chamber. The male luer tip may be removably connectable to a female luer connection of a vascular access device. The clip element includes a distal end, proximal end, and a pivot located between the distal end and the proximal end of the clip element for collapsing the deformable container to drive fluid out of the chamber by movement of the proximal end towards the distal end. The pivot may be a hinge, which may be in the form of a living hinge. The deformable container may be attached to the clip element. The locking element may be disposed on the clip element. A method of administering a fluid to a vascular access device using a single use pre-filled delivery device as described herein is also disclosed.

A delivery device includes a base body having an outlet opening and a chamber for receiving a flowable substance to be administered. The base body, having first and second film portions attached to each other by a connection with a plurality of regions, being configured to discharge the substance through the outlet opening by compressing the chamber. The delivery device further includes a pouring adapter tightly connected to the outlet opening. The plurality of regions of the connection include a more resilient region and a less resilient region that are arranged between the chamber and the outlet opening. When the chamber is compressed to discharge the substance through the outlet opening, the less resilient region is configured to come undone and the more resilient region is configured to remain connected so that the substance can be discharged solely through the outlet opening and the pouring adapter by compressing the chamber.

A blister strip which can be stuck onto the skin, is formed from at least two sheets and has an applicator for applying a medium contained in the blister to the skin, wherein the blister strip includes an upper sheet, with at least one protuberance, wherein the underside of the upper sheet, the underside enclosing the protuberance, is of adhesive configuration. The blister strip has a lower sheet, which covers the lower surface of the blister strip and can be drawn off from the adhesive underside of the upper sheet. The protuberance contains an applicator, separating the protuberance into at least two sub-volumes. Wherein the applicator has at least one opening, which connects two sub-volumes, wherein one sub-volume is located between the applicator and the lower sheet, and wherein at least one sub-volume is entirely surrounded by the inner surface of the protuberance and the applicator, and contains the medium.

A single use pre-filled delivery device is disclosed having a deformable container including a side wall having an inside surface defining a chamber for retaining fluid, a clip element, and a locking element. The deformable container further includes a closed proximal end and an open distal end including a male luer tip having a passageway therethrough providing fluid communication with the chamber. The male luer tip may be removably connectable to a female luer connection of a vascular access device. The clip element includes a distal end, proximal end, and a pivot located between the distal end and the proximal end of the clip element for collapsing the deformable container to drive fluid out of the chamber by movement of the proximal end towards the distal end. The pivot may be a hinge, which may be in the form of a living hinge. The deformable container may be attached to the clip element. The locking element may be disposed on the clip element. A method of administering a fluid to a vascular access device using a single use pre-filled delivery device as described herein is also disclosed.

This invention relates to a container (1) which is pre-filled or pre-fillable with one or more substances, such as a medical liquid and similar, comprising a squeezable activation compartment (2) intended to contain said one or more substances, a dispensing compartment (3) including a first portion (31) equipped with at least one dispensing member (311, 312, 314) of said one or more substances, and a second portion (32), wherein said second portion (32) of said dispensing compartment (3) and said activation compartment (2) are fluid-dynamically connected, and an activator element (4) arranged inside said container (1).

This invention also relates to a method for dispensing at least one substance by means of a container (1), and to a production method of a container (1).

The present invention relates to an opening and liquid supplying system (100) for pre-filled containers (10, 30) equipped with a supplying end, comprising a coupling element (20), connecting means (6) movable from a first position to a second position, and movable protection means (9); the coupling element (20) has an end (27) closed and suitable for being punched, and first guiding means (21) for guiding the movement of the connecting means (6) movable from the first position, close to the closed end (27), to the second position, apart from such end, and vice versa; the connecting means (6) have engaging means (7) for engaging with the protection means (9) so as to move integrally along a second degree of freedom, different than the first degree of freedom, and first matches (11) for the first guiding means (21). The invention relates also to a respective pre-filled container equipped with such system and the method for realize them.

A sealing container is designed to enable a user to adjust the timing of discharging the contents. The sealing container includes: a bag-shaped member for accommodating the contents therein, a sealing film for sealing the bag-shaped member, an opening means so configured that at least a part of which is movable toward the sealing film and is capable of opening the sealing film, an operation unit for performing an operation of moving the opening means, and a discharge means configured to be capable of discharging the contents from the bag-shaped member at a timing different from a timing at which the opening means penetrates the sealing film by operating the operation unit. It is possible for the user to perform only the operation of opening the sealing film by operating the operation unit, so that the user is able to arbitrarily adjust the timing at which the content is discharged from the bag-shaped member of the sealing container.

A blister strip which can be stuck onto the skin, is formed from at least two sheets and has an applicator for applying a medium contained in the blister to the skin, wherein the blister strip includes an upper sheet, with at least one protuberance, wherein the underside of the upper sheet, the underside enclosing the protuberance, is of adhesive configuration. The blister strip has a lower sheet, which covers the lower surface of the blister strip and can be drawn off from the adhesive underside of the upper sheet. The protuberance contains an applicator, separating the protuberance into at least two sub-volumes. Wherein the applicator has at least one opening, which connects two sub-volumes, wherein one sub-volume is located between the applicator and the lower sheet, and wherein at least one sub-volume is entirely surrounded by the inner surface of the protuberance and the applicator, and contains the medium.