A medical syringe useful for administering an injection or withdrawing a bodily fluid, the syringe comprising a barrel, plunger assembly and a needle assembly having a selectively retractable needle, the plunger assembly further comprising a plunger handle with a plunger seal and a front tip extending forwardly of the plunger seal to extend through the barrel and into the an annular fluid seal disposed in a recess between the barrel and a forwardly projecting needle, thereby reducing dead space inside the syringe and helping anchor the annular fluid seal inside the recess.

A syringe barrel includes: a barrel body including a nozzle portion at a distal end thereof; and a cap removably mounted to the nozzle portion and configured to seal a distal end opening of the nozzle portion. The cap includes: an inner cap formed of an elastic material and configured to come in liquid tight contact with the nozzle portion in a mounted state in which the cap is mounted to the nozzle portion, and a cylindrical outer cap formed of a material having a higher hardness than the inner cap and fixed around the inner cap. The inner cap includes: a base portion, and a cylindrical wall extending from the base portion in a proximal direction and surrounding the nozzle portion.

A glass syringe barrel is provided that has an at least partially conically shaped upper portion and a longitudinal axis. The glass syringe barrel has a top end through which a liquid can be ejected and a bottom end into which a plunger stopper can be pushed. The glass syringe barrel includes, in a direction from the top end to the bottom end, a cone, a shoulder region, and a body region. The shoulder region has and outer contour that has a concave and substantially circular arc-shaped area c.sub.1 with an outer radius r.sub.1. The outer contour of the glass syringe barrel in the shoulder region is defined by a certain minimum value the radius of curvature.

An assembly for an autoinjector device, the assembly including a syringe support for supporting a syringe by limiting forward axial movement of the syringe relative to the syringe support, and a guard element attachable to the syringe support by an attachment so that the guard element is axially restrained both axially forwardly and axially rearwardly relative to the syringe support by the attachment. Forwardly directed axial loads received by the guard element are transmitted to the syringe support via the attachment.

A drug injection device (10) including a housing (12) for holding a container (20) having a needle (24) for penetrating skin and a plunger (42) for expelling a drug stored in the container. The device includes visual and/or audible indicators for indicating that the correct depth of needle penetration has been achieved and that drug injection/extrusion has been started and/or completed. The device may further include a label (140) for visually confirming the quality of the drug contained therein. Alternatively, a tray (110) may be provided for receiving the drug injection device, which allows the quality of the drug contained therein to be visually confirmed.

A liquid preparation for application to an inner side of a hollow body to produce a sliding layer on a packaging for pharmaceuticals or cosmetic products comprises the following constituents: a reactive silicone system for forming a silicone network of the sliding layer, a catalyst for catalyzing the cross-linking reaction of the reactive silicone system, at least one unreactive silicone oil, and at least one diluent. The diluent comprises a silicon-containing compound and a content of the at least one diluent in the preparation amounts to more than 45 percent by weight and less than 95 percent by weight in the preparation.

A syringe includes a syringe body, a syringe cone having a distal opening, and a connection arranged in the region of the syringe cone, wherein the syringe body includes a first material and the connection includes a second material, and wherein the first material is different from the second material and the second material is a softer material than the first material.

Provided are a syringe assembly and a liquid-medicine administration device configured to suppress a variation in a pressure limit of a seal member. In the syringe assembly, the seal member is pressed and held between a pressing surface of a cap and a sealing surface of a distal nozzle portion of a syringe. The seal member is pressed and held in the axial direction in a pressing space over the whole region of an opposing portion between the pressing surface and the sealing surface, and a gap between the pressing surface and the sealing surface in the pressing space is narrowest on the inner peripheral side.

A device for administering needle-free subcutaneous treatment to a patient comprises an actuator configured to deliver a plurality of volumes of a treatment at a plurality of locations on a body of the patient; at least one imaging device configured to detect a movement of the needle-free device from a first location on the body of the patient to a second location on the body of the patient; and a processor configured to determine the second location on the body of the device relative to the first location from the movement of the needle-free device relative to the first location on the body, the processor further configured to determine a volume of the plurality of volumes of the treatment to deliver to the body of the patient at the second location.

A lock adapter, a syringe assembly, and a prefilled syringe capable of suppressing variation in position on the tip end side of the lock adapter after being subjected to an autoclave sterilization process. The lock adapter is attached to the periphery of a nozzle portion at the tip end of the prefilled syringe and slidable in an axial direction of the nozzle portion. The lock adapter includes: a cylindrical body portion surrounding the periphery of the nozzle portion; and a claw portion protruding to an inner peripheral side from a base end portion of the cylindrical body portion and configured to determine a tip end position of the lock adapter by being caught in an annular rib extending in a circumferential direction of the nozzle portion, in which the claw portion has a circumferential shape when viewed from the axial direction and is integrally connected in the circumferential direction.