Aspects of the present disclosure describe systems and methods for predicting an intra-aortic pressure of a patient receiving hemodynamic support from a transvalvular micro-axial heart pump. In some implementations, an intra-aortic pressure time series is derived from measurements of a pressure sensor of the transvalvular micro-axial heart pump and a motor speed time series is derived from a measured back electromotive force of a motor of the transvalvular micro-axial heart pump. Furthermore, in some implementations, machine learning algorithms, such as deep learning, are applied to the intra-aortic pressure and motor speed time series to accurately predict an intra-aortic pressure of the patient. In some implementations, the prediction is short-term (e.g., approximately 5 minutes in advance).

Aspects of the present disclosure describe systems and methods for predicting an intra-aortic pressure of a patient receiving hemodynamic support from a transvalvular micro-axial heart pump. In some implementations, an intra-aortic pressure time series is derived from measurements of a pressure sensor of the transvalvular micro-axial heart pump and a motor speed time series is derived from a measured back electromotive force of a motor of the transvalvular micro-axial heart pump. Furthermore, in some implementations, machine learning algorithms, such as deep learning, are applied to the intra-aortic pressure and motor speed time series to accurately predict an intra-aortic pressure of the patient. In some implementations, the prediction is short-term (e.g., approximately 5 minutes in advance).

A quick-connection type magnetic transmission apparatus for use in a medical interventional instrument, comprising a drive-side housing and a driven-side housing. The drive-side housing and the driven-side housing are coaxially arranged and are connected in a nested mode; a magnetic coupling structure, a magnetic coupling and coaxial guiding mechanism, and an integral coaxial guiding mechanism are sequentially comprised from inside to outside; the magnetic coupling structure consists of a magnetic transmission drive end (12), a magnetic transmission driven end (11), and a quick-connection separation sleeve (13); the magnetic coupling and coaxial guiding mechanism consists of a magnetic coupling and guiding sleeve (21) and a magnetic coupling and guiding groove (22); the integral coaxial guiding mechanism consists of a coaxial guiding sleeve (31), a coaxial guiding groove (32), and a coaxial locking structure. The quick-connection type magnetic transmission apparatus for use in the medical interventional instrument uses a double guiding-locking fit structure, achieves quick connection, and ensures a minimal transmission gap.

A quick-connection type magnetic transmission apparatus for use in a medical interventional instrument, comprising a drive-side housing and a driven-side housing. The drive-side housing and the driven-side housing are coaxially arranged and are connected in a nested mode; a magnetic coupling structure, a magnetic coupling and coaxial guiding mechanism, and an integral coaxial guiding mechanism are sequentially comprised from inside to outside; the magnetic coupling structure consists of a magnetic transmission drive end (12), a magnetic transmission driven end (11), and a quick-connection separation sleeve (13); the magnetic coupling and coaxial guiding mechanism consists of a magnetic coupling and guiding sleeve (21) and a magnetic coupling and guiding groove (22); the integral coaxial guiding mechanism consists of a coaxial guiding sleeve (31), a coaxial guiding groove (32), and a coaxial locking structure. The quick-connection type magnetic transmission apparatus for use in the medical interventional instrument uses a double guiding-locking fit structure, achieves quick connection, and ensures a minimal transmission gap.

An extracorporeal circulation blood pump and a method thereof are provided. A driving motor is driven to operate, and a rotating head rotates, thereby driving a rotator in a pump to rotate, an electromagnet is controlled to produce an axial upward attractive force on the rotator, so that the attraction force is matched with a coupling between driving permanent magnets and driven permanent magnets, and the rotator can rotate without contact in the axial direction. A first radial support permanent magnet and a second radial support permanent magnet are configured to interact with each other to generate a repulsive force, and the rotator can rotate without contact in the radial direction, achieving complete non-contact rotation with a pump housing, so as to enable a complex impeller to rotate without bearing support.

An extracorporeal circulation blood pump and a method thereof are provided. A driving motor is driven to operate, and a rotating head rotates, thereby driving a rotator in a pump to rotate, an electromagnet is controlled to produce an axial upward attractive force on the rotator, so that the attraction force is matched with a coupling between driving permanent magnets and driven permanent magnets, and the rotator can rotate without contact in the axial direction. A first radial support permanent magnet and a second radial support permanent magnet are configured to interact with each other to generate a repulsive force, and the rotator can rotate without contact in the radial direction, achieving complete non-contact rotation with a pump housing, so as to enable a complex impeller to rotate without bearing support.

A method of responding to an adverse event associated with an implantable blood pump including detecting the adverse event, reducing a pump speed of the blood pump relative to a set pump speed in response to the detected adverse event, and determining whether at least one of a group consisting of the adverse event and a second adverse event is present following the reducing of the pump speed of the blood pump. If the at least one of the group consisting of the adverse event and a second adverse event is not present, the method includes increasing the pump speed to the set pump speed and if the at least one of the group consisting of the adverse event and a second adverse event is present while increasing the pump speed to the set pump speed, the method includes reducing the pump speed to a maximum safe operating speed.

A method of responding to an adverse event associated with an implantable blood pump including detecting the adverse event, reducing a pump speed of the blood pump relative to a set pump speed in response to the detected adverse event, and determining whether at least one of a group consisting of the adverse event and a second adverse event is present following the reducing of the pump speed of the blood pump. If the at least one of the group consisting of the adverse event and a second adverse event is not present, the method includes increasing the pump speed to the set pump speed and if the at least one of the group consisting of the adverse event and a second adverse event is present while increasing the pump speed to the set pump speed, the method includes reducing the pump speed to a maximum safe operating speed.

A partially deformable impeller has at least two blades, wherein a periphery of each blade is deformable, the periphery being an outermost 5 to 20 percent of a width of the blade. In some embodiments, a catheter blood pump incorporates the partially deformable impeller.

A partially deformable impeller has at least two blades, wherein a periphery of each blade is deformable, the periphery being an outermost 5 to 20 percent of a width of the blade. In some embodiments, a catheter blood pump incorporates the partially deformable impeller.