Apparatus and methods are described for manufacturing a housing for an impeller of a blood pump. A frame is treated in order to enhance bonding between an inner surface of the frame and an inner lining. Subsequently, the inner lining is coupled to the inner surface of the frame along at least a portion of a central cylindrical portion of the frame. Subsequent to coupling the inner lining to the inner surface of the frame along at least a portion of the central cylindrical portion of the frame, a portion of an elongate tube is placed around at least a portion of the frame. While heating the inner lining, the frame, and the portion of the elongate tube, pressure is applied such as to cause the portion of the elongate tube to become coupled to the frame. Other applications are also described.

Apparatus and methods are described for manufacturing a housing for an impeller of a blood pump. A mandrel is placed inside an inner lining, with a central cylindrical portion of a frame disposed around the inner lining, the mandrel being shorter than a length of the inner lining. A portion of an elongate tube is placed around at least a portion of the frame. The inner lining, the frame and the portion of the elongate tube are heated, via the mandrel, and, while heating the inner lining, the frame, and the portion of the elongate tube, pressure is applied from outside the portion of the elongate tube, such as to cause the portion of the elongate tube to become coupled to the frame. Other applications are also described.

A catheter pump system is provided herein. The catheter pump system includes a catheter pump, a fluid system located within the catheter pump, and at least one filter membrane. The catheter pump has a proximal end, a distal end, and an elongate body extending therebetween, and the elongate body defining at least an inner lumen. The fluid system is configured to pressurize the catheter pump with fluid. The at least one filter membrane is configured to reduce an amount of particles within the fluid of the fluid system.

A catheter pump system is provided herein. The catheter pump system includes a catheter pump, a fluid system located within the catheter pump, and at least one filter membrane. The catheter pump has a proximal end, a distal end, and an elongate body extending therebetween, and the elongate body defining at least an inner lumen. The fluid system is configured to pressurize the catheter pump with fluid. The at least one filter membrane is configured to reduce an amount of particles within the fluid of the fluid system.

Apparatus and methods are described including a ventricular assist device that includes an impeller disposed within a frame and configured to pump blood through a pump-outlet tube and out of one of more blood outlet openings. The frame includes an inner lining. A protective braid is disposed over a distal portion of the frame and configured to block structures from the subject's left ventricle from entering into the frame. A proximal end of the protective braid is embedded between the pump-outlet tube and the inner lining, such that, during crimping of the frame, the braid becomes crimped with the pump-outlet tube and the inner lining, thereby preventing the braid from moving with respect to pump-outlet tube or the inner lining. Other applications are also described.

A circulatory support device includes a flexible cannula having a fluid outlet at a proximal end; and a pump assembly disposed at a distal end of the flexible cannula. The pump assembly includes a pump housing having a fluid inlet defined therein; a motor disposed within a distal end of the housing; and an impeller, driven to rotate by the motor, and configured to push blood toward the fluid outlet.

A percutaneous circulatory support device includes a housing and an impeller disposed within the housing. The impeller is rotatable relative to the housing to cause blood to flow through the percutaneous circulatory support device. The device further includes a reservoir disposed within the housing, and the reservoir carries at least one anticoagulant.

A ventricular support system including a light source, a fiber optic splitter, two or more filters, an intravascular blood pump having two or more sensor heads, and a photodetector is disclosed. At least some of the light transmitted by the light source is split by the fiber optic splitter such that a portion is transmitted to each of the two or more filters. Each portion of light is filtered by one of the two or more filters and transmitted to one of the two or more sensor heads. Light beams reflected from each of the two or more sensor heads are combined by the fiber optic splitter. At least some of the combined light beams are received by the photodetector. By only using a single light source and a single photodetector with the two or more sensor heads, the ventricular support system may have improved portability.

A ventricular support system including a light source, a fiber optic splitter, two or more filters, an intravascular blood pump having two or more sensor heads, and a photodetector is disclosed. At least some of the light transmitted by the light source is split by the fiber optic splitter such that a portion is transmitted to each of the two or more filters. Each portion of light is filtered by one of the two or more filters and transmitted to one of the two or more sensor heads. Light beams reflected from each of the two or more sensor heads are combined by the fiber optic splitter. At least some of the combined light beams are received by the photodetector. By only using a single light source and a single photodetector with the two or more sensor heads, the ventricular support system may have improved portability.

An implantable renal replacement therapy device may include: a first catheter configured to be inserted into a blood vessel in a subject's body; a pump in fluid communication with the first catheter, the pump is configured to pump subject's blood from the blood vessel; a filter in fluid communication with the pump, the filter is configured to: receive the subject's blood from the pump, and filter the received blood to provide a filtered blood and a filtrate liquid, wherein the filter is in fluid communication with the first catheter to cause an outflow of the filtered blood from the filter to the blood vessel; and a second catheter in fluid communication with the filter and configured to be inserted into an urinary bladder in the subject's body to cause an outflow of the filtrate liquid from the filter to the urinary bladder.