Disclosed are an adhesive transparent electrode and a method of fabricating the same. More particularly, an adhesive transparent electrode according to an embodiment of the present disclosure includes a substrate and an adhesive silicone-based polymer matrix, in which a metal nanowire network is embedded, deposited on the substrate, wherein the adhesive silicone-based polymer matrix includes a silicone-based polymer including a silicone-based polymer base and a silicone-based polymer crosslinker; and a non-ionic surfactant.

The present invention provides a biomedical electrode composition capable of forming a living body contact layer for a biomedical electrode that is excellent in conductivity and biocompatibility, is light-weight, can be manufactured at low cost, and can control significant reduction in conductivity even though the biomedical electrode is soaked in water or dried. The present invention was accomplished by a biomedical electrode composition including a polymer compound having both the ionic repeating unit “a” and the repeating unit “b” of (meth)acrylate, in which the ionic repeating unit “a” is a repeating unit of sodium salt, potassium salt, or ammonium salt including a partial structure represented by the following general formula (1), and the repeating unit “b” of (meth)acrylate is a repeating unit represented by the following general formula (2). ##STR00001##

The present disclosure provides devices and methods for delivering a biomolecule into a cell. A delivery device of the present disclosure includes a first reservoir, a second reservoir, a porous membrane comprising a nanopore, and two or more electrodes configured to generate an electric field across the porous membrane for delivery of a biomolecule present in the second reservoir through the nanopore of the porous membrane and into a cell present in the first reservoir.

An ophthalmic device including a hydrogel-based material body that can encapsulate a reservoir housing a therapeutic and a metal electrode covering the reservoir. The therapeutic can be delivered into an eye by way of electrodissolution of the metal electrode. The electrodissolution can be enhanced by the presence of chloride ions proximal to the metal electrode, and the ophthalmic device can be engineered to ensure the presence of chloride ions proximal to the metal electrode.

A therapy electrode apparatus for dispensing conductive gel to skin of a patient wearing a wearable defibrillator includes a therapy electrode, at least one reservoir comprising the conductive gel, and a gel deployment device comprising at least two reactive chemicals. The at least one reservoir is configured to release the conductive gel between the therapy electrode and a patient's skin prior to a delivery of one or more therapeutic shocks. The gel deployment device configured to, on receiving a treatment signal from a controller of the wearable defibrillator operably connected to the gel deployment device, cause the at least two reactive chemicals to come into contact to produce a pressurized fluid to release the conductive gel from the at least one reservoir between the therapy electrode and the patient's skin.

Provided is a new means for suppressing inflammation or suppressing inflammatory cytokine production. Provided is a device in which a weak pulse current is passed through a living body or living tissue to suppress inflammation in the living body or the living tissue. This device is provided with a power supply means, and a current control means for receiving a supply of power to intermittently apply a direct current at prescribed intervals, and is configured such that the current control means includes a pulse width modulation control means, and the pulse width modulation control means generates a pulse wave that is a rectangular wave, and in which the time indicating a peak value for rising in one cycle of the pulse wave (“pulse duration”) is at least 0.1 millisecond, the peak value is 1.0-20 V, inclusive, and the duty ratio of the pulse wave is at least 5.5%.

One aspect relates to a method for manufacturing a medical electrode, including providing an electrically insulating substrate material, on which a conductor track is arranged; applying a continuous metal layer, which at least partially covers the substrate material, and the conductor track, so that an electrically conducting connection is formed between the metal layer and the conductor track; and partially removing the metal layer to form an electrode segment, which has an electrically conducting connection to the conductor track.

A Carbon NanoTube (CNT) composite electrode includes a lower electrode having a through-hole formed therein, and configured to be attached to the skin of a subject body to detect a biosignal, an upper electrode provided on one surface of the lower electrode to form an enclosed space between the lower electrode and the upper electrode, and configured to receive the biosignal detected by the lower electrode, and an air discharge portion formed in at least one of the lower electrode and the upper electrode, and discharging air present in the enclosed space and the through-hole externally so as to be configured to allow the upper electrode and the lower electrode to be attached to the skin of the subject body via vacuum suction.

A therapy electrode apparatus for dispensing conductive gel to skin of a patient wearing a wearable defibrillator includes a therapy electrode, at least one reservoir comprising the conductive gel, and a gel deployment device comprising at least two reactive chemicals. The at least one reservoir is configured to release the conductive gel between the therapy electrode and a patient's skin prior to a delivery of one or more therapeutic shocks. The gel deployment device configured to, on receiving a treatment signal from a controller of the wearable defibrillator operably connected to the gel deployment device, cause the at least two reactive chemicals to come into contact to produce a pressurized fluid to release the conductive gel from the at least one reservoir between the therapy electrode and the patient's skin.

Systems, devices and methods for providing a pressurized fluid for facilitating conductive gel release prior to providing cardiac therapy to a patient are disclosed. A first system can include a chemical reaction chamber including a first chemical and a second chemical isolated from each other by a mechanical barrier. The mechanical barrier is configured to be compromised upon receiving a signal from an electrotherapy device controller such that the first chemical and second chemical come into contact to produce a sufficient amount of pressurized fluid. An alternative system can include a pressure source comprising a reservoir containing a pressurized fluid. The pressure source can also include at least one release mechanism configured to cause a release of the pressurized fluid from the reservoir to an exit port of the pressure source when a wearable medical device is preparing to deliver a therapeutic shock to a patient.