A method and apparatus of electrode interfaces for stimulating neurons and nerve cells that provides micro-fabricated electrode interfaces configured for conformal placement adjacent to neuron, nerves and neural tissue to thereby allow the neuron, nerves and neural tissue to grow around the electrode interfaces and allow for the creation depending on configuration of local or far electrical fields and current flows to stimulate them.

A handheld implantation device for implantation of a retinal tissue implant at an implantation site. The handheld implantation device includes a handheld implantation tool having a leading implantation tool end and a trailing implantation tool end, an implant holder for peripherally holding a retinal tissue implant including an uppermost viable retinal tissue and a lowermost basement membrane and a clinician-operated attachment arrangement for initial attaching the implant holder at the leading implantation tool end and subsequent selected detaching the implant holder therefrom at the implantation site for implantation of the implant holder together with the retinal tissue implant thereat.

A retinal electrode device according to an embodiment comprises: a base, a first wing connected to a first side part of the base, wherein a first folding line is defined between the base and the first wing, and a plurality of electrodes installed on at least one of the base and the first wing, wherein the retinal electrode device may be configured to have a first form in which the first wing is folded on the base along the folding line and a second form in which the first wing is unfolded on the base along the folding line.

Disclosed is an artificial retinal stimulator and an artificial retinal device which are for providing image jittering. The artificial retinal stimulator for providing the image jittering includes: a photodiode configured to sense light stimulation and generate a current based on an intensity of the stimulation; a pulse generator configured to generate a pulse to be provided to a corresponding stimulation electrode on the basis of the current coming from the photodiode; a switch configured to connect an output terminal of the pulse generator and ground; and a jittering switch configured to determine whether to transfer the generated pulse to the corresponding stimulation electrode or to transfer to a stimulation electrode corresponding to another artificial retinal stimulator. According to the present disclosure, an image jittering function capable of emulating an eye blinking effect is provided, so that it is possible to enable a low vision patient to see images better.

Methods and systems monitor and assess brain bioimpedance through the use of an ocular window that assesses dynamic changes in cerebral blood volume (CBV). That ocular window is implemented through an ocular bioimpedance device that, in a non-invasive manner, measures numerous different brain health indicators using the bioimpedance measurements collected through the regions around the eyes. The ocular bioimpedance device may be goggles with localized measurement electrodes that include cathodes and anodes.

An optical sensor, especially an artificial retina, that includes at least one photosensitive cell. Each cell includes a integration capacitor, a read circuit the operation of which depends on the charge of the integration capacitor, at least one MOS transistor operating subthreshold, and the drain-source current of which influences the charge on the integration capacitor, and at least one photodiode operating in photovoltaic mode and connected to the gate of this transistor, such that the drain-source current of the MOS transistor depends on the optical power received by the photodiode.

The present invention relates to the field of medical devices, and specifically to a packaging structure and a packaging method for a retinal prosthesis implanted chip, including a high-density stimulation electrode component processed by a glass substrate, wherein the stimulation electrode component comprises the glass substrate, and a plurality of stimulation electrodes and a pad structure provided on the glass substrate; the stimulation electrodes are formed through cutting out metal pins on the metal and then pouring with glass; the stimulation electrode component is connected to an ASIC chip; a glass packaging cover is covered on the ASIC chip, the glass packaging cover is provided with a metal feedthrough structure for communicating with the stimulation chip; and the packaging cover covers and encapsulates the pad structure. In the packaging structure of the present invention, the substrate and the packaging cover are both made of a glass material, and thereby enable manufacture of a high-density stimulation electrode array, and the metal feedthrough structure is directly used on the glass cover, which facilitates wiring and achieves good sealing performance of the package cover.

A lens including a flexible refractive optic having a fixed refractive index, an electro-active element embedded within the flexible refractive optic, wherein the electro-active element has an alterable refractive index, and a controller electrically connected to the electro-active element wherein when power is applied thereto the refractive index of the electro-active element is altered.

A method, including the action of operating a sense prosthesis, such as a retinal implant, according to a first operating regime while the recipient has a first fatigue level, and operating the sense prosthesis according to a second operating regime while the recipient has a second fatigue level that is greater than the first fatigue level.

A biomedical device having improved handling features to be easily inserted into a cavity or recess is disclosed, as well as methods for using thereof, said device comprising a flat and soft substrate, comprising electrically conductive tracks, configured to interface a biological surface; and a rigid member located on a portion of said flat and soft substrate, said member being substantially composed of a mechanically adaptive material being fully or partially degradable upon a degrading/softening trigger.