An example of a system for delivering neurostimulation energy may include a programming control circuit and a user interface. The programming control circuit may be configured to generate stimulation parameters according to a neurostimulation program including a pattern of interferential stimulation configured to effect asynchronous and/or non-regular activation of nerve fibers by simultaneously delivering a first stimulation current having a first waveform with a first frequency using a first electrode configuration and a second stimulation current having a second waveform with a second frequency using a second electrode configuration. The user interface may be configured to determine the neurostimulation program and to provide the pattern of interferential stimulation with modulation of the first waveform, the second waveform, the first electrode configuration, and/or the second electrode configuration to result in a time-varying beat frequency capable of effecting the asynchronous and/or non-regular activation of the nerve fibers.

An electrical interferential technique is used to determine operable treatment parameters which are then used to apply a treatment to a patient. A range of beat frequencies is applied to the patient and an indicator of autonomic nervous system activity is measured. When some degree of autonomic nervous system activity is detected, a subsequent trial is conducted using an overlaying range of frequencies, a narrower range or a single frequency, in an attempt to fine tune the reaction of the autonomic nervous system. The subsequent trial may use a different measure of activity of the autonomic nervous system. A garment having a series of electrode sites thereon may be used for a partially trained person to correctly apply electrodes to the patient's body. The treatments may be conducted while the patient is asleep.

Supplying a transcranial alternating current neurostimulation signal to a human brain is shown. A first signal is supplied at a first frequency to said human brain, in combination with a second signal at a second frequency. A third signal at a third frequency is created due to interference between the first signal and the second signal.

An example system for exciting a selected set of motor neurons of a patient comprises one or more signal generators configured for generating a first electrical signal and a second electrical signal; a first set of wires configured to provide the first electrical signal to a first set of electrodes, wherein the first set of electrodes are configured for being secured to a first set of positions on the patient; a second set of wires configured to provide the second electrical signal to a second set of electrodes, wherein the second set of electrodes are configured for being secured to a second set of positions on the patient; and a controller configured to control operation of the one or more signal generators. The first electrical signal is a periodic signal of a first frequency. The second electrical signal is a periodic signal of a second frequency. The first frequency and the second frequency differ by a non-zero frequency difference. The first signal is provided to the first electrodes and the second signal is provided to the second electrodes for exciting the set of motor neurons of the patient.

When treating a subject using alternating electric fields (e.g., using TTFields to treat a tumor), some subjects experience an electrosensation effect when the alternating electric field switches direction. This application describes a variety of approaches for reducing or eliminating this electrosensation. More specifically, during the course of treatment using alternating electric fields, additional electrical signals that reduce the subject's sensation are applied during each of a plurality of time intervals, and these additional electrical signals interact with the relevant nerve cells to reduce the sensations.

A method and apparatus for treating bone or other infection in a patient to minimize the number of limb amputations which employs a unique, three-dimensional software-controlled electronic phased array amplifier system using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a defined infected area containing electrically-conductive ionic solutions so as to obtain 100% treatment using low or high voltage, low current that delivers electrical stimulation (ES) using a low DC current through and or around the defined infection treatment area. The minimally invasive treatment of the infection requires no radiation or chemotherapy that could be harmful to the patient.

An apparatus for providing electrostimulation of a biological tissue, the apparatus comprising: a first electrical signal provider for providing a first alternating electric field in the biological tissue, the first alternating electric field having a first frequency; a second electrical signal provider for providing a second alternating electric field in the biological tissue the second alternating electric field having a second frequency; wherein the first alternating electric field and the second alternating electric field provide a combined field in the biological tissue, and the apparatus comprises a controller configured to provide variations of at least one of the first frequency and the second frequency so that the combined field provides a pulsed interferential stimulation signal.

Methods and systems for neurostimulation are provided. In one example, a neurostimulation system may include a stimulation module, the stimulation module providing a first stimulation block and a second stimulation block. The neurostimulation system may further include a stimulation interference estimation module for providing an interference model for estimating a spatial interference between the first stimulation block and the second stimulation block. In some examples, the stimulation interference estimation module may reconfigure one or more of the first and the second stimulation blocks to reduce temporal overlap of the stimulation blocks.

A remedial signal for potentially harmful radiation that is emitted by a portable electronic battery powered communication device is implemented directly within the handset of the portable communication device the portable communication device is operated by a microprocessor and the remedial signal module is controlled by an algorithm in the microprocessor wherein the algorithm obtains information concerning radio frequency communications associated with the portable telecommunications device from the transceivers of the device.

Selective high-frequency spinal chord modulation for inhibiting pain with reduced side affects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal chord region to address low back pain without creating unwanted sensory and/or motor side affects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.