Systems and methods for assessing compliance with position therapy. In an embodiment, position therapy is provided to a user while the user is wearing a position therapy device. The position therapy comprises, by the device, collecting positional data, determining positions of the user over a time period based on the positional data, and, when it is determined that the user is in a target position, providing feedback to the user to influence the user to change to a non-target position. In addition, the device stores a duration of use in its memory. The duration of use indicates a duration that the user has used the wearable position therapy device in each of one or more positions. An assessment of the user's compliance with the position therapy is then provided based, at least in part, on the duration of use.

Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.

A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

A trans mucosal neuromuscular electrical stimulation device including a mouthpiece, electrodes associated with the mouthpiece. The device and/or mouthpiece incorporates electrical circuitry operatively connecting to the electrodes to a power source and is configured to provide, in use, electrical stimulation to one or more palate and/or tongue muscles via the electrodes through the oral mucosa. The treatment regime, including the location of stimulation and the parameters used, is designed to increase resting muscle tone and/or muscle tone during sleep.

The disclosed subject matter is directed to a surgical implant and a device for its activation. The surgical implant comprises a substantially planar central body portion having a top side and a bottom side and at least two adjustable wing portions. In addition, the implant comprises at least two connecting members, each one of the at least two connecting members extending from opposite sides of the central body portion, the each one of the at least two connecting members being configured for flexibly connecting each one of the at least two wing portions at opposite sides to said central body portion.

A system and method for restoring inspiratory muscle function to restore breathing and expiratory muscle function to restore an effective cough in the same individual, wherein the systems that selectively activate the inspiratory or expiratory muscle function are separately ground to limit or prevent the flow of electrical current to both the expiratory and inspiratory muscles at the same time and to avoid damaging either neuromuscular system. Also described is the method by which the inspiratory or expiratory muscles are activated selectively to optimize the action of the inspiratory muscles to restore breathing and to optimize the action of the expiratory muscles to restore cough.

A method of providing a sleep apnea nerve stimulation therapy to a subject may include detecting a respiratory waveform of the subject with a sensor. The sensor may be configured for coupling to the subject. The respiratory waveform may include a plurality of respiratory cycles each corresponding to at least one of a breath and an attempted breath of the subject. The method may also include identifying a breathing pattern within the respiratory waveform over a period of time. The breathing pattern may include a repeating pattern of a plurality of respiratory cycles followed by at least one respiratory cycle corresponding to a disordered breathing event. The method may also include generating a series of stimulation pulses with an implantable nerve stimulator configured for coupling to a hypoglossal nerve of the subject. The series of stimulation pulses may be coordinated with the breathing pattern.

The invention relates to medicine, The technical result of the present invention is to increase the efficiency of treatment of the respiratory system pathologies. The system includes a communication unit connected to a ventilator, a human-machine interface unit, a data processing, storage and management unit, an algorithmic unit, a pulse generation unit, a unit of electromyography electrodes and a stimulation.

Methods and systems for treating sleep apnea using electrical stimulation to a patient's upper and/or lower respiratory nerve or muscle are described. A stimulation regimen can be used to achieve upper airway patency and/or rhythmic air flow in a coordinated fashion during sleep. In some cases, diaphragm activity is monitored to determine whether sufficient upper airway patency and/or rhythmic air flow is achieved and maintained. The stimulation regimen may be adjusted based on the diaphragm activity. In some cases, the system includes modularized components so that the components can be customized to an individual's needs.

Apnea events may be detected based on a primary biomarker, e.g., respiration, in the one or more physiological signals. The apnea events may be characterized as one of an obstructive sleep apnea (OSA) event, a central sleep apnea (CSA) event, or a combination OSA/CSA event based on a secondary biomarker, e.g., a frequency spectrum or a morphology of the respirations in the one or more physiological signals. A first electrical stimulation may be provided to treat OSA in response to a first one or more of the apnea events being characterized as OSA events. A second electrical stimulation may be provided to treat CSA in response to a second one or more of apnea events being characterized as CSA events. A third electrical stimulation may be provided to treat combination OSA/CSA in response to a third one or more of the apnea events being characterized as combination OSA/CSA events.