A method of evaluating an implantation of a lead is disclosed. Via a graphical user interface of an electronic device, a visual representation of a sacrum of the patient and a lead that is implanted in the sacrum is displayed. The lead includes a plurality of electrode contacts. An evaluation is made as to how well the lead has been implanted in the sacrum based on the visual representation of the sacrum and the lead. The evaluating comprises: determining whether the lead is inserted in a predetermined region of the sacrum, determining how far a predetermined one of the electrode contacts is located from an edge of the sacrum, and determining a degree of curvature of the lead.

Systems and methods for stimulating the sensory cortex of an individual by obtaining a neuronal stimulation signal adapted to provide a movement cue for the individual and transmitting the neuronal stimulation signal to an electric contact of a neuronal stimulation electrode that is already implanted into the brain of the individual for a purpose different from providing the movement cue. Proprioceptive information is communicated to the individual by obtaining information about the body posture of the individual and applying a neuronal stimulation signal to an afferent axon targeting a sensory neuron in the cortex of the individual. The neuronal stimulation signal is determined based on the obtained body posture information and corresponds to the proprioceptive information. A first neuronal stimulation signal providing the movement cue and a second neuronal stimulation signal providing the proprioceptive information may be applied together to the cortex of the individual.

A method of providing a sleep apnea nerve stimulation therapy to a subject may include detecting a respiratory waveform of the subject with a sensor. The sensor may be configured for coupling to the subject. The respiratory waveform may include a plurality of respiratory cycles each corresponding to at least one of a breath and an attempted breath of the subject. The method may also include identifying a breathing pattern within the respiratory waveform over a period of time. The breathing pattern may include a repeating pattern of a plurality of respiratory cycles followed by at least one respiratory cycle corresponding to a disordered breathing event. The method may also include generating a series of stimulation pulses with an implantable nerve stimulator configured for coupling to a hypoglossal nerve of the subject. The series of stimulation pulses may be coordinated with the breathing pattern.

Disclosed herein are methods, devices, and systems for evaluation, diagnosis, prevention, and treatment of peripheral neuropathies.

Disclosed herein are systems and methods for increasing performance, improving sleep and improving relaxation that involve specifically coordinating nerve stimulation of a cranial nerve (e.g. vagus nerve) in conjunction with augmented reality (AR). According to certain embodiments disclosed are systems that include an AR component that presents information or a stimulus and provides cranial nerve fiber stimulation (CNFS) at strategic times to reduce anxiety/arousal/related during user activity or scenarios and reinforce learning.

A sensory unit for implant-supported dental implants or prostheses. The main unit is composed of two or more subunits, or devices. One of the units is placed in the region of the implant head, and will have the function of transforming the mechanical forces into an electrical signal. It can also be placed in the masticatory region of implant supported bridges or overdenture, to perform the same function, i.e., transforming mechanical loads into an electrical signal. A second unit, will receive by a wired or wireless electronic communication the electrical signal, and will convert it into a neurological stimulus perceived sensorially by the sensory endings of the trigeminal nerve, unilaterally, or bilaterally. This second unit will be arranged in the submucosa, in the vicinity of the nerve ending, taking advantage of the anatomical depressions or recesses in the region, and will establish a gradient of neurological stimulation towards the nerve ending.

Disclosed are various examples and embodiments of systems, devices, components and methods configured to treat mood disorders in a patient using a compact implantable neurostimulator and corresponding lead(s) that are shaped, sized and configured to be implanted beneath a patient's skin in the head or neck, and to stimulate one or more target cranial nerves. The one or more medical electrical leads comprising electrode(s) are positioned adjacent to, in contact with, or in operative positional relationship to, the one or more target cranial nerves of the patient. In some embodiments, electrical stimulation is provided to the one or more target cranial nerve(s) of the patient for periods of time ranging between 30 and 60 minutes, once or twice per day. In some embodiments, power is provided to the implantable neurostimulator transcutaneously by inductive, wireless, RF, acoustic, microwave, or other suitable non-invasive means.

Devices, systems, and techniques are disclosed for determining spatial relationships between electrodes implanted within a patient. In one example, a medical device delivers, via a first electrode, an electrical stimulus and senses, for each other electrode, a respective electrical signal indicative of the electrical stimulus. The medical device determines, for each other electrode, a respective value for each respective electrical signal. The medical device determines, based on the respective values for each respective electrical signal and values of tissue conductivity of tissues of the patient interposed between the first electrode and the other electrodes, spatial relationships between the first electrode and each other electrode of the plurality of electrodes.

Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is associated with a neurovascular bundle, can re-programme immune cells in the spleen, modulate pro- and anti-inflammatory molecules levels, and induce disease-resolution pathways system-ically thereby reducing inflammation and providing ways of treating inflammatory disorders. The invention provides improved ways of treating inflammatory disorders which minimize off-target effects.

Systems and methods are provided for electrical stimulation using electrical neurostimulators to treat neurological disorders. In exemplary implementations, the systems and methods effectuate selective sensory transmission block by spatially and temporally patterned multichannel, closed-loop electrical stimulation of neural tissue across the intervertebral foramina. The systems and methods optimize stimulation parameters according to the conduction velocity of afferents leading to effective neural transmission block. The systems and methods provide a dramatic improvement of selective transmission block, e.g., in a sub-population of unmyelinated C-fibers and slow-conducting Aδ fibers, by combining spatial, frequency and temporal parameters in the disclosed stimulation paradigm. An optimized start and termination of the stimulation may be implemented, as desired, thereby reducing overall energy consumption by reducing the stimulus strength during the maintenance phase of neural transmission block.