A jaundice diagnosis and treatment system includes a control circuit, a bilirubin measurement assembly, a risk evaluation circuit and a display assembly, wherein the bilirubin measurement assembly is communicatively connected to the control circuit, and is used for measuring a bilirubin concentration of a newborn baby and transmitting the measured bilirubin concentration to the control circuit, so that the control circuit generates measurement data according to the measured bilirubin concentration; the risk evaluation circuit is communicatively connected to the control circuit, and is used for acquiring the measurement data from the control circuit and evaluating a pathologic jaundice risk level according to the measurement data; and the display assembly is connected to the control circuit, and is used for displaying the measurement data and/or the pathologic jaundice risk level under the control of the control circuit.

In an embodiment, the present disclosure pertains to a method of determining optimal parameters for application of light from a light source to a tissue. In general, the method includes one or more of the following steps of: (1) utilizing an algorithm to generate results related to estimating light flow from the light source into the tissue; and (2) utilizing the results to determine optimal parameters for applying the light source to the tissue. In some embodiments, the method of the present disclosure further includes the step of: (3) applying the light source to the tissue using the optimal parameters; and (4) treating a condition associated with the tissue.

According to an aspect, there is provided an apparatus for use with a treatment device for providing feedback to a user on a treatment operation performed on a body part of a subject, wherein the treatment device is configured to apply light pulses to skin of the body part to perform the treatment operation, wherein a light pulse applied to the skin treats an area of the skin. The apparatus comprises a processing unit configured to receive a first measurement signal from a first sensor, the first measurement signal comprising information about positions and/or movements of the treatment device over time; for a light pulse previously applied by the treatment device to the body part during the treatment operation, process the first measurement signal to estimate a previous treatment position as a position of the treatment device relative to the body part when the light pulse was generated; for the previously applied light pulse and based on the estimated previous treatment position, estimate a previous treatment area for the light pulse corresponding to the area of skin of the body part that the light pulse was applied to when the treatment device was at the previous treatment position; process the first measurement signal to estimate a current position of the treatment device relative to the body part; based on the estimated current position of the treatment device, estimate a current treatment area corresponding to an area of skin that the treatment device would apply a light pulse to while in the current position; and generate a feedback control signal for a feedback unit, wherein the feedback control signal is configured to cause the feedback unit to generate feedback indicating whether the current treatment area corresponds, or substantially corresponds, to a previous treatment area.

The present disclosure relates to systems, methods, and uses of systems treating a skin condition with phototherapy. A system comprises (a) a phototherapy device comprising a phototherapy light source; (b) a patient computing device comprising a processor and a memory, the patient computing device configured to: transmit a first signal to the phototherapy device enabling operation of the phototherapy device according to one or more conditional prescription parameters, activate the phototherapy light source, and transmit a second signal reporting operation of the phototherapy device; and (c) a server configured to communicate with the patient computing device and receive the second signal. Also disclosed are systems, methods and compositions for controlling phototherapy treatments of the skin comprising (a) incorporating sun exposure into a prescribed phototherapy treatment; (b) quantitative measurement of erythema using digital image processing; (c) computer aided guidance for administration of targeted phototherapy; (d) treatment recommendations from outcome based analytics of a population of connected phototherapy devices; (e) an emollient with UV fading dye to visibly identify treated areas in the administration of targeted phototherapy.

Systems tune, control, or remediate the intrinsic Circadian clock. A light controller sets spectral distribution, intensity of a bioactive spectral band to shift or entrain circadian response to enhance performance and/or synchronize with local or expected conditions. The systems enhance performance under conditions that might be changing, disrupted, or otherwise present an irregular phase or unnatural change in the subject's circadian status, for example, due to geographically discontinuous activity or spectrally deficient workplace illumination, or due to divergent individual sleep/wake behaviors of subjects in a structured group activity. An illumination recipe that compensates for the deficiency of lighting or of participant sleep or behavior patterns, or age- or disease-related changes, to evoke, shift, or align circadian response and improve behaviors such as classroom alertness, relaxation, excitability, attention, or focus. Systems may receive sensed light values and automatically apply high- and/or low-CER illumination to effect the intended circadian phase.

A phototherapy system for treating a user can include an applicator, a controller, and a communication cable configured to couple the applicator and the controller. The applicator can include a light source, a thermal sensor, and a fan. The controller can be in communication with the applicator. The controller can be configured to receive a predetermined treatment regimen to be applied to the user via the applicator. A method for treating skin presenting psoriasis includes providing a phototherapy system. The user can select a skin type on the controller. The use can place the applicator adjacent to the skin presenting psoriasis, eczema, or vitiligo. The user can receive a light therapy treatment from the applicator, whereby the psoriasis, eczema, or vitiligo has been treated.

A therapeutic light delivery apparatus and method are disclosed. The apparatus includes a light source and an integrated optical applicator. The integrated optical applicator includes a plurality of light emitting devices and detector fibers fixedly spatially positioned within a flexible matrix material. The light emitting devices can be positioned a predetermined distance from an application side of the integrated optical applicator comprising an accurate and repeatable standoff position. A flexible matrix material is disclosed having a high scattering coefficient to produce a uniform irradiance pattern and predetermined fluence. A method of performing a photodynamic therapy procedure is disclosed that includes providing an integrated optical applicator couple to a therapy light source, providing a photosensitizing drug to a tissue of a patient, positioning an application side of the integrated optical applicator against a target area of the tissue, delivering a therapy light to the target area, and producing an irradiance pattern.

A light irradiation device includes a first light source emitting first light in a visible wavelength band and a second light source emitting second light, in which at least part of a wavelength band is different from a wavelength band of the first light source and which catalyzes synthesis of a functional substance in a target to which light is applied. The second light includes light in a wavelength band of ultraviolet B.

The present invention refers to a device to transfer heat and infrared energy with dynamic temperature control and homogeneous heat distribution that places one or more applicator modules on an affected area, later with a control module you can resort to a predefined therapy according to the affected area and some personal data of the patient, or to a therapy provided by the therapist, or even to set a temperature at which the device will heat up; the invention also refers to the manufacturing process of said device. The user can define the time interval that the therapy will last. Alternatively, the user may use a mobile application to control, monitor and personalize therapies, which he or his therapist may define from the mobile application or from a web application, where said pair of applications will be connected to a web API for data synchronization.

A method for evaluating the effectiveness of a skin treatment on a skin feature includes correcting the color of a first image before the skin treatment, correcting the color of a second image after the skin treatment, determining the sizes of the skin feature in the first and second images, and comparing the corrected colors and sizes of the skin feature in the first and second images. In some embodiments, the first and second images include the skin feature and an indicator adjacent to the skin feature, where the indicator has a standard color and a known size.