A negative-pressure cup structure includes a negative-pressure cup body and a light therapy module. The negative-pressure cup body has a rim. The light therapy module is received in the negative-pressure cup body and includes a circuit board and multiple light-emitting diodes (LEDs) mounted on the circuit board and irradiating corresponding to the rim. Therefore, the negative-pressure cup structure further has functions of light therapy and skin care.

The present invention is directed to a tandem-structured bio-organic light emitting diode (bio-OLED) for photodynamic therapy, and to a photodynamic therapy device including the same to convert a red light emitted from the bio-organic light emitting diode into a near-infrared light (NIR) emission, thereby enabling the use of a PBM therapy in a wide wavelength range of 600 to 1,000 nm.

Embodiments may provide self-guided, self-directed diagnostics and treatment of neural conditions. For example, a system may comprise a processor, memory accessible by the processor, and program instructions and data stored in the memory, a plurality of stimulation devices connected to signal output circuitry interfacing the processor with the stimulation devices, program instructions and data to control the stimulation devices to generate and transmit stimulation signals, a plurality of sensing devices connected to signal input circuitry interfacing the processor with the sensing devices, program instructions and data to receive sensed signals from the sensing devices, a communication device adapted to wirelessly communicate with a server computer system, and program instructions and data to perform dynamic closed loop feedback of the stimulation signals based on the received sensed signals to provide self-guided, self-directed diagnostics and treatment of neural conditions using at least one recipe for a treatment strategy guided by artificial intelligence.

Four dimensional (4D) energy-field package assembly for projecting energy fields according to a 4D coordinate function. The 4D energy-field package assembly includes an energy-source system having energy sources capable of providing energy to energy locations, and energy waveguides for directing energy from the energy locations from one side of the energy waveguide to another side of the energy waveguide along energy propagation paths.

Systems and methods for treating sexual dysfunction using transcranial photobiomodulation (t-PBM) with near infrared light (NIR) are provided. In particular, a device configured for treating a disorder of a subject, the device can have a power source and a light source configured to receive power from the power source to cause the light source to emit near infrared light, wherein the near-infrared light has a wavelength of 600 nm to 1400 nm. The device has a processor and a housing configured to position the light source to deliver the near infrared light to a region of interest of the subject via transcranial photobiomodulation in a dosimetry and duration sufficient to treat the disorder.

An LED exterior luminaire comprising light-emitting diodes (LEDs) with a circadian-adjustable light output mode for its medical safety comprises at least two switchable LED chip chains I and III, wherein chain I comprising at least one LED chip emitting orange light from a wavelength range of 580 nm to 610 nm and at least one LED chip emitting red light from a wavelength range of 610 nm to 700 nm, chain III comprising at least one blue LED chip overlaid with a luminophore emitting a continuous band spectrum of visible light from a wavelength range of 440 nm to 700 nm and a correlated color temperature CCT of 2200 to 4200 K, wherein chains I and III are each separately connected to a power source via a dimming ballast that regulates the proportion of input current to each chain separately.

Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter. LED lighting systems, methods, and devices can switch between a daytime configuration and a night time configuration, wherein the daytime configuration provides unfiltered light and the night time configuration provides filtered light.

A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.

A handheld light therapy device may include a plurality of LEDs selected from a group of colors including red, green, blue, and near infrared, a first and second end, and a light color controller. The first end includes a handle for holding the apparatus and the second end includes the plurality of LEDs. The light color controller receives a light color signal from a user and outputs a polychromatic light corresponding to the light color input signal from at least two of the plurality of LEDs.

The present invention comprises methods and devices for modulating the activity or activities of living cells, such as cells found in or derived from humans, animals, plants, insects, microorganisms and other organisms. Methods of the present invention comprise use of the application of ultrasound, such as low intensity, low frequency ultrasound, to living cells to affect the cells and modulate the cells' activities. Devices of the present invention comprise one or more components for generating ultrasound waves, such as ultrasonic emitters, transducers or piezoelectric transducers, composite transducers, CMUTs, and which may be provided as single or multiple transducers or in an array configurations. The ultrasound waves may be of any shape, and may be focused or unfocused.