A61N2005/1085

Diffusing alpha-emitter radiation therapy for breast and prostate cancer

A method for treating a tumor, comprising identifying a tumor as a breast cancer or prostate cancer tumor and implanting in the tumor identified as a breast cancer or prostate cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 8 MBq hour, per centimeter length.

Diffusing alpha-emitter radiation therapy for colon cancer

A method for treating a tumor, comprising identifying a tumor as a colon cancer tumor and implanting in the tumor identified as a colon cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 3.5 Mega becquerel (MBq) hour and 8.4 MBq hour, per centimeter length.

Neutron beam transmission adjusting device comprising a neutron beam transmission unit including a neutron reactant, method for producing neutron beam transmission adjusting device, and neutron beam adjusting method

Provided is a neutron beam transmission adjusting device including a neutron beam transmission unit including a neutron reactant and capable of modulating an energy and/or a flux of a neutron beam transmitted through the neutron beam transmission unit.

Radiation therapy device and system

The present disclosure provides a radiation therapy device and system. The radiation therapy device includes a first treatment head and a second treatment head. A beam emitted from the second treatment head intersects with a beam emitted from the first treatment head at an intersection point. The first treatment head is an X-ray treatment head, and the second treatment head is an X-ray treatment head, a multi-source focusing treatment head, or an intensity-modulated treatment head. The radiation therapy device may increase a dose rate at the intersection point.

PARTICLE BEAM GUN CONTROL SYSTEMS AND METHODS
20230040534 · 2023-02-09 ·

Presented systems and methods facilitate efficient and effective monitoring of particle beams. In some embodiments, a radiation gun system comprises: a particle beam gun that generates a particle beam, and a gun control component that controls the gun particle beam generation characteristics, including particle beam fidelity characteristics. The particle beam characteristics can be compatible with FLASH radiation therapy. Resolution control of the particle beam generation can enable dose delivery at an intra-pulse level and micro-bunch level. The micro-bunch can include individual bunches per each 3 GHz RF cycle within the 5 to 15 μsec pulse-width. The FLASH radiation therapy dose delivery can have a bunch level resolution of approximately 4.4×10{circumflex over ( )}-6 cGy/bunch.

Particle beam gun control systems and methods

Presented systems and methods facilitate efficient and effective monitoring of particle beams. In some embodiments, a radiation gun system comprises: a particle beam gun that generates a particle beam, and a gun control component that controls the gun particle beam generation characteristics, including particle beam fidelity characteristics. The particle beam characteristics can be compatible with FLASH radiation therapy. Resolution control of the particle beam generation can enable dose delivery at an intra-pulse level and micro-bunch level. The micro-bunch can include individual bunches per each 3 GHz RF cycle within the 5 to 15 μsec pulse-width. The FLASH radiation therapy dose delivery can have a bunch level resolution of approximately 4.4×10{circumflex over ( )}−6cGy/bunch.

Diffusing alpha-emitter radiation therapy for prostate cancer

A method for treating a tumor, comprising identifying a tumor as a prostate cancer tumor and implanting in the tumor identified as a prostate cancer tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 7 Mega becquerel (MBq) hour and 14.7 MBq hour, per centimeter length.

Diffusing alpha-emitter radiation therapy for squamous cell carcinoma

A method for treating a tumor, comprising identifying a tumor as a squamous cell carcinoma tumor and implanting in the tumor identified as a squamous cell carcinoma tumor, as least one diffusing alpha-emitter radiation therapy (DaRT) source (21) with a suitable radon release rate and for a given duration, such that the source (21) provides during the given duration a cumulated activity of released radon between 3.7 Mega becquerel (MBq) hour and 8.6 MBq hour, per centimeter length.

CIRCULAR ACCELERATOR AND PARTICLE THERAPY SYSTEM
20230180378 · 2023-06-08 ·

There is provided a circular accelerator that accelerates a beam of charged particles circulating in a magnetic field such that a closed orbit for each energy of the beam is eccentric. The circular accelerator includes a beam extraction port for extracting beams of different energies from the closed orbit, a first bending magnet and a second bending magnet that bend the beam extracted from the beam extraction port, and a control unit that controls magnetic field strengths of the first bending magnet and the second bending magnet in accordance with the energy of the extracted beam. When the energy of the extracted beam is a designed maximum energy of the circular accelerator, the control unit excites both the first bending magnet and the second bending magnet to bend the beam.

Radiation dosage monitoring system

Some embodiments are directed to a radiation dosage monitoring system including a model generation module configured to generate a 3D surface model of a portion of a patient undergoing radiation treatment, an image detector configured to detect Cherenkov radiation and any subsequent secondary and scattered radiation originating due to the initial Cherenkov radiation emitted from the patient, a processing module configured to determine estimations of radiation applied to the patient utilizing the images from the image detector and the 3D model, and to utilize the determined estimations of radiation applied to the patient together with data indicative of the orientation of a radiation beam inducing emission of the Cherenkov radiation at a time when the radiation beam was applied to generate a 3D internal representation of the location of the portions of a irradiated patient resulting in the emission of the Cherenkov radiation.