A computing system comprising a central processing unit (CPU), and memory coupled to the CPU and having stored therein instructions that, when executed by the computing system, cause the computing system to execute operations to generate a radiation treatment plan. The operations include accessing a minimum prescribed dose to be delivered into and across the target, determining a number of beams and directions of the beams, and determining a beam energy for each of the beams, wherein the number of beams, the directions of the beams, and the beam energy for each of the beams are determined such that the entire target receives the minimum prescribed dose. The operations further include prescribing a dose rate and optimizing dose rate constraints for FLASH therapy, and displaying a dose rate map of the FLASH therapy.

A beam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The material of the moderator is subjected to a powder sintering process using a powder sintering device so as to change powders or a power compact into blocks. The reflector leads the neutrons deviated from the main axis back. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

The invention comprises a method and apparatus for tracking and/or imaging impact of a particle beam treating a tumor using one or more imaging systems positionable about the tumor, such as a positron emission tracking and/or imaging system, where resulting tracking/imaging data: dynamically determines a treatment beam position, tracks a history of treatment beam positions, guides the treatment beam, and/or images a tumor before, during, and/or after treatment with the charged particle beam.

A reusable joint for a medical linac, a reusable CF choke flange for a medical linac, a linac and a method for forming a reusable joint for a medical linac are disclosed. The reusable joint comprises a CF choke flange, a CF cover flange and a gasket. The CF choke flange comprises a first waveguide aperture, a choke groove and a first CF groove comprising a first knife-edge, wherein the choke groove is disposed radially inwards from the first CF groove on the CF choke flange. The CF cover flange comprises a second waveguide aperture aligned with the first waveguide aperture and a second CF groove comprising a second knife-edge and aligned with the first CF groove. The gasket is disposed between and in contact with the first CF groove and the second CF groove.

An example particle therapy system includes a toroid-shaped gantry having a central axis. The toroid-shaped gantry has a cover. The cover includes one or more segments that are rotatable at least partly around the central axis of the toroid-shaped gantry to create an unobstructed opening in the toroid-shaped gantry. The particle therapy system includes a patient couch configured to move relative to a hole in the toroid-shaped gantry, an imaging system coupled to an interior of the toroid-shaped gantry and configured for rotation about the hole in the toroid-shaped gantry, where the imaging system is configured to capture images of a patient on the patient couch, and a nozzle coupled to the interior of the toroid-shaped gantry and configured for rotation about the hole in the toroid-shaped gantry. The nozzle is configured to deliver radiation to a target in the patient based on one or more of the images.

Disclosed herein is a method of positioning a patient for radio-therapy treatment using a radiotherapy device. The method comprises determining an identity of a treatment beam that is to be used to treat the patient, determining an offset between a reference location and an isocentre location for the identified treatment beam that is to be used to treat the patient, and changing a spatial relationship between the patient and at least a part of the radiotherapy device, according to the determined offset.

A beam shaping assembly (10) used in a neutron capture system and capable of changing an irradiation range of a neutron beam. The beam shaping assembly includes: a beam inlet (11), a target (12), a moderator (13) adjoining the target (12), a reflector (14) surrounding the moderator (13), a thermal neutron absorber (15) adjoining the moderator (13), a radiation shield (16) arranged inside the beam shaping assembly (10), and a beam outlet (17). The beam shaping assembly (10) further includes replacement components (21, 22) that can be attached to and detached from the beam shaping assembly (10) to change the irradiation range of the neutron beam.

Described are devices, systems, and methods for modulating the spectral energy distribution produced by an x-ray source via control of the energy of the x-ray-generating electron beam, e.g., for energy-modulated radiation therapy or other purposes. In some embodiments, such energy modulation is achieved by an add-on device to a linear accelerator. Also disclosed are computational methods and computer program products for planning energy-modulated therapy.

Described are devices, systems, and methods for modulating the spectral energy distribution produced by an x-ray source via control of the energy of the x-ray-generating electron beam, e.g., for energy-modulated radiation therapy or other purposes. In some embodiments, such energy modulation is achieved by an add-on device to a linear accelerator. Also disclosed are computational methods and computer program products for planning energy-modulated therapy.

A system and method for delivering radiation therapy to a patient includes generating a radiation therapy plan and adjusting a shape of at least one of a plurality of multi-leaf collimators (MLCs) arranged in an arc about a patient bed to create a respective plurality of desired beam profiles for each of the plurality of MLCs to thereby implement the ultrafast radiation therapy plan delivery. The method further includes control a radiation therapy source to execute the radiation therapy plan by creating the respective plurality of desired beam profiles for each of the plurality of MLCs.