A portable, light-weight ultrasound therapy system includes a wearable garment and a flexible ultrasound device. The flexible ultrasound device includes a plurality of piezoelectric transducers. A control system is configured to couple the flexible ultrasound device to an external processing system configured to control operation of the plurality of piezoelectric transducers.

An ultrasound-assisted wound cleanser in the form of a handheld device includes an integrated vibration motor, an integrated ultrasound generator, an integrated energy source for the vibration motor and the ultrasound generator, and a replaceable cleansing attachment which can be driven by the vibration motor for abrasively removing wound coatings. The cleansing attachment has an acoustic transducer which is designed to convert the electric oscillations generated by the ultrasound generator into sound waves, a device for reinforcing and/or distributing and/or transferring the ultrasound waves, and bristles and/or lamellas for the abrasive removal. Further, a method for cleansing wounds includes moving a cleansing attachment with bristles for abrasively removing wound coatings by a vibration motor. The cleansing attachment is oscillated by an ultrasound generator, and the oscillations for supporting the removal of wound coatings are transmitted into the wound via a transmission medium.

Human and animal biofilms and pathogens are treated with extracorporeal acoustic pressure shock waves at a location of prosthesis or implant in a body.

An electroceutical apparatus and self-care method for treating pain by providing Transcutaneous Electrical Nerve Stimulation (TENS) in combination with pulsed Ultrasound or Light Emitting Diode (LED) treatments. In some embodiments, the apparatus includes a pod unit and a controller, and wrap for holding the pod unit on an area of a user's body. In some embodiments, the wrap may include electrodes and the intensity of the TENS treatment may be adjusted by a user via the controller. In some embodiments, the frequency or output of the treatments is fixed and sequentially delivered to the user in a timed manner.

Catheter-based devices and associated methods for immune system neuromodulation of human patients are disclosed herein. One aspect of the present technology is directed to methods of treating a human patient diagnosed with an immune system condition. The methods can include intravascularly positioning a neuromodulation catheter within a blood vessel proximate to neural fibers innervating an immune system organ of the patient. The method also includes reducing sympathetic neural activity in the patient by delivering energy to the neural fibers innervating the immune system organ via the neuromodulation catheter. Reducing sympathetic neural activity improves a measurable physiological parameter corresponding to the immune system condition of the patient.

Disclosed embodiments relate to apparatuses and methods for wound treatment with ultrasound. In certain embodiments, therapeutic ultrasound wound treatment apparatus includes a wound dressing configured to be positioned over a wound to provide a substantially fluid impermeable seal over the wound and a transducer to deliver therapeutic ultrasound to tissue. The therapeutic ultrasound wound treatment apparatus may further include a wound contact layer configured to be positioned in contact with the wound, a transmission layer positioned above the wound contact layer, an absorbent layer positioned above the transmission layer and configured to absorb wound fluid, and a backing layer positioned above the absorbent layer and including an orifice. Also disclosed are multiple parameters for the therapeutic ultrasound signal.

The invention relates to medical therapy of detrimental lesions. A system treats with non-invasive arrays of non-ionizing energy-radiation sources. The external sources focus energy dose distribution to a selected volume in a body. Energy output is directed towards a pathologic location and quenched around other sites or healthy tissue. Beam aiming is done without source movement. Targeted, volumetrically discrete energy deposition can beneficially manipulate lesions within the body. The purpose of the focused and enhanced energy deposition is to repair or disable pathologic physiology or structures, nerve pathways, extracellular fluid, and misfolded proteins. Locally augmented energy is used to enhance immunity, release pharmaceutical compounds from energy-sensitive vesicles and reconfigure or eliminate misfolded proteins and their aggregates. Targeted tissue may have enhanced sensitivity to received energy via a non-ionizing-radiation, treatment-localizing agent. This system optimizes delivery of non-ionizing, non-ablating electromagnetic or mechanical energy, degrading or repairing an abnormality upon interaction with it.

A method of treating an infected implant by administering acoustic shock waves to an implant area or region encompassing an implantation, includes the steps of activating acoustic shock waves of an acoustic shock wave generator to emit acoustic shock waves and subjecting the implant area to acoustic shock waves stimulating the implant area or region. The emitted acoustic shock waves are focused or unfocused acoustic shock waves, or acoustic pressure waves, generated electrohydraulically, electromagnetically, radially, or via a piezo electric generating system.

An apparatus includes a conical body defining a chamber configured to contain a liquid and having a nozzle located a front end of the conical body and configured to discharge a stream of the liquid, a rear wall positioned at a rear of the conical body and at least partially defining the chamber, an inlet in communication with the chamber for introducing the liquid into the chamber, an acoustic transducer positioned at the rear wall, the acoustic transducer configured to generate acoustic energy and to introduce the acoustic energy into the liquid contained in the chamber, and an exhaust system including a vent in communication with the chamber to remove a mixture of liquid and gas bubbles from the chamber, an exhaust leading away from the vent, and an outlet in communication with the exhaust and configured to discharge the liquid and gas bubbles into or adjacent to the stream.

Antibiotics are administered in a surgical site subcutaneously via a small or stab incision in the surgical field. Transcutaneous ultrasonic vibrations are applied across the surgical field, which is then opened in the usual manner, to thereby provide a surgical field which contains a vastly higher and more effective level of antibiotic. At the same time the underlying tissue is hydrated.