An ultrasound imaging device includes: a first transmitter configured to transmit a transmission signal to at least one piezoelectric element; a receiver configured to receive a reception signal from the at least one piezoelectric element; a second transmitter configured to transmit a given signal to the at least one piezoelectric element; a timing controller configured to control a transmitting timing at which the first transmitter transmits the transmission signal and a receiving timing at which the receiver receives the reception signal; and a signal controller configured to cause the second transmitter to transmit the given signal to a first area to which the first transmitter does not transmit the transmission signal at the transmitting timing or cause the second transmitter to transmit the given signal to a second area from which the receiver does not receive the reception signal at the receiving timing.

Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.

The present invention relates to an implantable device (1) comprising: an ultrasonic unit (11) which includes an electric connection terminal, a support plate (12) which includes a through-opening for the connection terminal to pass through, and an attachment piece (13) which can cooperate with the connection terminal, the attachment piece (13) including a collar for pressing the support plate (12) against the ultrasonic unit (11) when the ultrasonic unit (11), the support plate (12) and the attachment piece (13) are joined.

A catheter comprises a catheter shaft having a fluid channel, an ultrasound transducer and a compliant balloon mounted on the catheter shaft and having an interior in fluid communication with the fluid channel and containing the ultrasound transducer. The compliant balloon includes a balloon wall having a working section radially surrounding the ultrasound transducer. The working section has a predetermined straightness when the working section has a first diameter and when the working section has a second diameter that is at least 2 mm greater than the first diameter. Other embodiments are also described and claimed.

A tissue treatment system and method of using the tissue treatment system determines a size of a body lumen, or a neuromodulation parameter corresponding to the size of the body lumen. The tissue treatment system fills a balloon with a fluid when the balloon is within a body lumen. A fluid parameter of the fluid is detected over a period of time. A parameter curve of the fluid parameter is determined. The parameter curve includes the fluid parameter versus an independent variable over the period of time. The system compares the parameter curve of the fluid parameter to a reference curve and, based on the comparison, determine the body lumen size or the neuromodulation parameter. Other embodiments are also described and claimed.

A catheter system for ablation of tissue around a blood vessel, e.g., the pulmonary artery, to reduce neural activity of nerves surrounding the blood vessel. The catheter system includes an elongate shaft having a proximal portion coupled to a handle, and a distal portion. The distal portion includes a transducer and an expandable anchor, which may be actuated to transition between a collapsed delivery state and an expanded deployed state where the anchor centralizes the transducer within the blood vessel. The transducer may be actuated to emit energy to reduce neural activity of the nerves surrounding the blood vessel. Systems and method are further provided for confirming that neural activity of the nerves surround the blood vessel has been sufficiently reduced.

A medical apparatus for mitigating formation of kidney stones in a human patient can include or use a turbulence generator deployable into a renal pelvis of a human kidney, the generator comprising an element configured to produce an acoustic wave in a medium within the renal pelvis, and an actuator configured such as to manipulate the turbulence generator; wherein one of the turbulence generator or the actuator can be configured for coupling with a source of power.

Method for ameliorating secondary pulmonary hypertension in a patient including determining a pulmonary vascular resistance (PVR) of the patient suffering from secondary pulmonary hypertension; assessing a change in the PVR in response to a selection treatment; and treating the patient with a pulmonary artery manipulation device to provide pulmonary artery denervation if the patient is determined to suffer from fixed PH, thereby ameliorating the secondary pulmonary hypertension of the patient.

A catheter for ultrasonic-driven bladder therapeutic agent delivery, including: a tube having a proximal expandable portion and a distal end, and at least one transducer sleeve accommodating at least one ultrasound transducer mounted on the tube between the proximal expandable portion and the distal end.

Systems and methods for treating eating disorders using electro-physiologically active transducer intragastric balloon system (“EAT system”) are described herein. The EAT System includes an intragastric balloon that is configured to operate in a typical fashion and further modified to include an integrated electro-physiological stimulation unit. The stimulation unit is configured to generate impulses using a transducer that are suitable for stimulating sensory receptors located around the stomach. In particular, transducer transmits mechanical waves through the fluid within the IG balloon and its outer shell to any receptors of the vagus nerve system that are located in the vicinity of the IG balloon. Controlled stimulation of the vagus nerve fibers using the stimulation unit can effectively produce appetite controlling sensations of satiety beyond the typical efficacy period of an unmodified IG balloon.