A method of applying a skin peel formulation or product that includes providing a skin peel formulation or product containing at least 10% of the total weight of the skin peel formulation or product being vitamin A. Also provided is vitamin C present in at least 20% of the total weight of the skin peel formulation or product, wherein the vitamin C is in oil soluble form. The skin peel formulation is applied to a region of the body without any acid pre-treatments. After application of the skin peel formulation the user waits at least 25 days before reapplying the skin peel formulation again.

Disclosed is a cosmetic or dermatological preparation which comprises one or more extracts of Saxifraga oppositifolia (purple saxifrage) and/or one or more extracts of Soldanella alpina (alpine snowbell). The use of these extracts to combat extrinsic and intrinsic skin aging is likewise described.

Methods and compositions related to the selective, specific disruption of multiple ligand-receptor signaling interactions, such as ligand-receptor interactions implicated in disease, are disclosed. These interactions may involve multiple cytokines in a single receptor family or multiple ligand receptor interactions from at least two distinct ligand-receptor families. The compositions may comprise polypeptides having composite sequences that comprise sequence fragments of two or more ligand binding sites. The methods and compositions may involve sequence fragments of two or more ligand binding sites that are arranged to conserve the secondary structure of each of the ligands from which the sequence fragments were taken.

Disclosed herein is a multi-compartment container and methods of use thereof where the container is comprised of a first and a second aerosol chamber proximate to one another; a spray nozzle; and a spray nozzle retention device, wherein the spray nozzle is operably coupled to the spray nozzle retention device such that the spray nozzle can be operably engaged with the first aerosol chamber and then moved to separate from the first aerosol chamber and operably engage with the second aerosol chamber by movement of at least a portion of the spray nozzle retention device.

The present disclosure relates to, inter alia, a formulation in a package, the formulation comprises one or more active agents and is co-mingled with a whipping agent prior to being filled under pressure into the package. The whipping agent is added in sufficient amounts to be dispersed in the formulation. The pressurized package is under sufficient pressure suitable to maintain the whipping agent dispersed in the formulation; and the pressurized package is under sufficient pressure to expel the formulation as a whipped formulation upon application of external force on the formulation in the package.

Compositions and topical formulations comprising a PPAR agonist complex comprising glyceryl linoleate, glyceryl linolenate, xymenynic acid, and Pterocarpus marsupium bark extract are described herein. Methods of inducing skin barrier repair, increasing the biosynthesis of barrier lipids and proteins in the skin, stimulating hair growth, treating acne and combinations thereof utilizing the composition and topical formulations are also provided herein.

A cosmetic composition includes a compound of the following chemical formula as an active ingredient. A method for regenerating skin includes applying an effective amount of the cosmetic composition to skin: ##STR00001## wherein R.sup.1 to R.sup.7 are independently a substituted or unsubstituted C1 to C20 alkyl group.

Uncultured amniotic cell and protein fraction products derived from amniotic fluid and methods of preparing and using those compositions are provided. According to the methods of the present invention, uncultured amniotic cell and protein products may be derived from a large sample of amniotic fluid to provide a higher concentration of tissue regeneration components. Described are methods for separating uncultured amniotic cells or protein fractions from other components of amniotic fluid and the resulting uncultured amniotic cell and protein products. Furthermore, the present invention includes methods for delivering the uncultured amniotic cell and protein products to the skin and eye, including before, during, or after a treatment procedure.

A moisturizing lotion composition includes water and propylene glycol having a concentration of 21.0 to 37.5 wt % of the moisturizing lotion composition. In addition, the moisturizing lotion composition includes aloe vera having a concentration of 0.50 to 4.0 wt % of the moisturizing lotion composition, and vervain extract having a concentration of 0.50 to 4.0 wt % of the moisturizing lotion composition. In addition, the moisturizing lotion composition includes willow bark extract having a concentration of 0.50 to 0.20 wt % of the moisturizing lotion composition. Further, the moisturizing lotion composition includes chamomilla recutita extract having a concentration of 0.05 to 0.40 wt % of the moisturizing lotion composition, wherein a ratio of the concentration of the propylene glycol to the concentration of the chamomilla recutita extract is between 4.5 and 5.5.

Provided are a method for preventing or treating photoaging of skin, including: administering a composition comprising an effective amount of an extract of Agastache rugosa O Kuntze to a subject in need thereof. The composition decreases expression of matrix metalloproteinases (MMPs) induced by ultraviolet B (UVB) irradiation; decreases expression of mitogen-activated protein kinase (MAPK)/activator protein-1 (AP-1) signaling; improves collagen synthesis; decreases skin inflammation induced by NF-κB; and decreases oxidative stress induced by UVB irradiation.