A pump and valve arrangement (201), a dialysis system (10) comprising the pump and valve arrangement 201 and a method of operating a pump and valve arrangement (201). The pump and valve arrangement (201) has a dialyser having a semi-permeable membrane. The pump and valve arrangement (201) delivers dialysis fluid to and from the dialyser (12). The pump and valve arrangement (201) has a control system (450) configured to shuttle dialysis fluid between an inlet pump assembly and the dialyser (12) one or more times so as to agitate the surface of the semi-permeable membrane of the dialyser (12).

Disclosed herein is a forward osmosis module for concentration and/or crystallization salts from an aqueous feed solution, the feed solution including seeds that surround an open semi-permeable membrane having free membrane portions forming an enclosure with a distribution pipe that introduces draw solution inside said enclosure. The feed solution penetrates into the enclosure as permeate from the feed side of the membrane to the draw solution side according to a Forward Osmosis process based on net driving pressure. The draw solution with permeate is evacuated from the enclosure via an outlet. A generator applies, at least periodically, a plurality of directional gauge pressure strokes PGs, directed from at least one of the draw solution inlet and outlet thereby effecting mechanical shaking of the free membrane portions for detachment of foulant.

The present disclosure relates to hollow fiber tangential flow filters, including hollow fiber tangential flow depth filters, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.

A method of activating and dewatering sludge through application of acoustic pressure shock waves to wastewater.

Apparatus and method for semi-permeable membrane cleaning in particular, applying series of pulsed water stroke, made simultaneously with osmosis backward flow causing superposed membrane directional shaking and fouling detachment. Pulsed water stroke provided by water stroke generator as several momentum sharp changes in gauge pressure and induce velocity pulse of residual brine flow. The pulsed water strokes ideally induce resonance in the membrane. Osmosis backward wash may be provided either by injection for predetermined injection time, additional solution selected in such way that net driving pressure becomes opposite to normal osmotic operation thereby providing a backward flow of permeate towards to the side opposite to normal operation mode, so as to lift said foulant, or by throttling permeate exiting from the permeate enclosure, until the net driving pressure value become equal to zero, during application of precise synchronized and opposing brine and permeate pressure strokes thereby providing a plurality of quick RO-FO-RO process changes. These procedures allow a membrane to be kept continuously clean and operate at higher recovery.

The invention relates to a method for the processing of protein-containing suspensions or solutions, for example for concentrating or purifying the protein-containing particles or dissolved protein-containing substance contained in the suspensions or solutions, wherein the protein-containing suspensions or solutions are filtered by means of a filter module and the protein-containing particles or dissolved protein-containing substance retained in the filter module are conveyed out of the filter module by means of a backwashing fluid.

A method of filtering a fluid with components includes providing an alternating pressure. The alternating pressure yields an oscillating transmembrane pressure through volume and pressure variations within a filtration chamber while sealing the filtration chamber. A separation surface can be housed in the filtration chamber wherein an influent is introduced. Components can be concentrated on the separation surface, effectively removing some or all of them from the fluid. To flush the filtration chamber and separation surface, a backwash fluid and components can be introduced and removed from the filtration chamber. While both the components are being concentrated and backwashed, the system can maintain the oscillating transmembrane pressure and varying volume and pressure relative to the separation surface.

The present disclosure relates to hollow fiber tangential flow filters, including hollow fiber tangential flow depth filters, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.

A water filter unit for purifying water fed to the water filter unit. The unit includes a containment defined by a wall section, first and second end sections, wherein the wall section is attached to the first end section and the second end section; a water inlet arranged in the first or second end section through which the water is fed into the containment; a filter membrane arranged in the containment such that at least part of the water is fed through the filter membrane; and a first water outlet for filtered water from the membrane. The unit further includes an injector pump arranged to create an increased flow velocity trough the injector pump of the water fed to the filter membrane, and the injector pump is furthermore arranged to receive unfiltered water not fed through the membrane and recirculate the unfiltered water within the containment.

A filtration cell (10) for a biological sample including an upper chamber for receiving the biological sample to be filtered, a lower chamber in fluid communication with the upper chamber, and a filtration membrane (14) positioned between the upper chamber and the lower chamber is disclosed. A surface of the filtration membrane has a contact angle >90°. The flow of the biological sample through the upper chamber may be tangential to the filtration membrane and a filtrate passing through the filtration membrane may be collected in the lower chamber. Also, a method of filtering a biological sample including passing the biological sample through an upper chamber of a filtration cell as described above and collecting a filtrate in the lower chamber is disclosed.