A filter plate frame assembly and a horizontal filter press, in which accidental over pressurization of the filter diaphragm is prevented. A filter plate frame assembly having a separate subframe is provided with a limited vertical travel with respect to the filter frame and the filter plate, such that the subframe is allowed to drop away from the filter plate when the filter chamber is opened. This enables a diaphragm to be attached to the subframe such that an escape route is formed for a pressurized medium accidentally introduced between the filter plate and the diaphragm. Moreover, the limited travel of the subframe allows the subframe to be pressed towards the filter plate when the filter chamber is closed, thereby allowing normal operation of the diaphragm for squeezing a filter cake.

A filter diaphragm for a horizontal plate and frame-type filter, such as a tower press, including a sheet like body and at least on a filter plate-facing side thereof, a continuous seal bead. The seal bead includes an inner seal lip on a lateral inside of the seal bead and an outer seal lip surrounding the inner seal lip on a lateral outside of the seal bead. The outer seal lip is elevated from the inner seal lip in a vertical direction perpendicular to a general plane defined by the diaphragm.

A filter diaphragm for a horizontal plate and frame-type filter, such as a tower press, including a sheet like body and at least on a filter plate-facing side thereof, a continuous seal bead. The seal bead includes an inner seal lip on a lateral inside of the seal bead and an outer seal lip surrounding the inner seal lip on a lateral outside of the seal bead. The outer seal lip is elevated from the inner seal lip in a vertical direction perpendicular to a general plane defined by the diaphragm.

The present invention relates to modification to permeate channels and permeate materials in a cross-flow filtration system to improve performance in counter current filtration having both retentate channels and permeate channels wherein a solution is pumped through one of the channels and drawn through a membrane to one of the other channels to assist in positive pressure driven filtration by using the osmotic pressure, concentration, or preferential solubility difference between the retentate and permeate flow streams thereby increasing or altering the flux through the membrane separating the flow streams.

The present invention relates to modification to permeate channels and permeate materials in a cross-flow filtration system to improve performance in counter current filtration having both retentate channels and permeate channels wherein a solution is pumped through one of the channels and drawn through a membrane to one of the other channels to assist in positive pressure driven filtration by using the osmotic pressure, concentration, or preferential solubility difference between the retentate and permeate flow streams thereby increasing or altering the flux through the membrane separating the flow streams.

A filter plate frame assembly with a filter plate frame and a subframe housed within the frame, such that the subframe can be removed from the frame without removing the frame from the filter press. In this way, consumable components can be provided in connection with the subframe, which can be easily removed from the filter press. This, in turn, makes replacement of worn components faster, as the whole frame does not need to be removed from the filter press. An associated horizontal filter press and a method of replacing worn components of such a filter press is also provided.

A filter plate frame assembly with a filter plate frame and a subframe housed within the frame, such that the subframe can be removed from the frame without removing the frame from the filter press. In this way, consumable components can be provided in connection with the subframe, which can be easily removed from the filter press. This, in turn, makes replacement of worn components faster, as the whole frame does not need to be removed from the filter press. An associated horizontal filter press and a method of replacing worn components of such a filter press is also provided.

A filter press device includes a supporting frame and elongated side rails disposed parallel and horizontally on the supporting frame. A following head assembly is disposed on an end portion of the supporting frame, and a following head assembly is movably disposed on another end portion of the supporting frame. The elongated side rails support a combination of filter plates of varying sizes through one or more adapters. An adapter plate interposes between adjacent filter plates of different sizes, providing fluidic communication between the different sized filter plates.

A disposable cell enrichment kit includes a crossflow filtration device configured to be disposed along a main loop pathway and to receive a process volume containing a biological sample and utilize crossflow filtration, via a micro-porous membrane, to retain a specific cell population in a retentate from the process volume and to remove a permeate including certain biological components from the process volume. The crossflow filtration device includes a laminated filtration unit that includes the micro-porous membrane, a first mating portion, a second mating portion, and a membrane support. The membrane support includes a first plurality of structural features that define a first plurality of openings, wherein the first plurality of structural features are coupled to the micro-porous membrane and provide support to the micro-porous membrane, and the first plurality of openings allow the permeate to flow through them after crossing the micro-porous membrane.

An outlet cover with a first attachment pin fixed with respect to the outlet cover and having a radially extendable portion deformable upon by a radial force exerted from a hollow inside of the first attachment pin. The radially deformable portion prevents the first attachment pin from being withdrawn from an associated attachment hole, while allowing the first attachment pin to be compressed further into the associated attachment hole, thereby preventing a securing element from stripping any retaining surface, and thus increasing the longevity of the outlet cover. An associated filter plate, filter plate assembly and a filter are also concerned.