A sterile solution product bag includes sterilization grade filter integrated directly into the product bag such that microbial and particulate matter filtration can be performed using the filter directly at the point of fill. The filter can include a hollow fiber filter membrane contained in a stem connected to a bladder of the product bag.

A method for manufacturing a hollow fiber membrane module, the hollow fiber membrane module including: a hollow fiber membrane bundle including a plurality of hollow fiber membranes; a housing configured to contain the hollow fiber membrane bundle; and a potting part in which a potting agent is added between an outer surface of the hollow fiber membranes and an inner surface of the housing at both end regions or at one end region of the hollow fiber membrane bundle, wherein the method including: providing a sheet-shaped spacer in a space between the hollow fiber membranes at the both end regions or at the one end region of the hollow fiber membrane bundle; and adding a potting agent between the outer surface of the hollow fiber membranes and the inner surface of the housing at the both end regions or at the one end region of the hollow fiber membrane bundle such that the provided spacer is embedded, wherein the potting agent includes resin, rubber, or elastomer, as a main ingredient, and wherein the spacer is a net, a non-woven fabric, a porous sheet, or a film.

An external circulation-type hollow fiber membrane module which has a high processing capacity and which is capable of inhibiting a to-be-treated liquid within a case from flowing through a short path and efficiently bringing the liquid into contact with a hollow fiber membrane in whichever direction of a vertical direction, a horizontal direction, etc., the liquid flows. An external circulation-type hollow fiber membrane module is provided with: a hollow fiber membrane bundle; a case; and a short-path prevention body that blocks flowing of a to-be-treated liquid in a gap between the hollow fiber membrane bundle and the case, wherein a first end of the hollow fiber membrane bundle is fixed in the case, and the short-path prevention body is provided to the downstream side of a first port which is a liquid flow-in port in the case so as to project from the inner surface of the case.

A membrane module comprising a hollow fiber membrane bundle with a longitudinal extent, a membrane bundle cross section and a first and a second bundle end, the bundle comprising a multitude of hollow fiber membranes extending between the first and the second bundle end, and also comprising, within the membrane bundle cross section, a proportion of threads which are arranged between the hollow fiber membranes and which keep the hollow fiber membranes apart. The arrangement of the threads between the hollow fiber membranes is such that at the first bundle end and/or at the second bundle end the hollow fiber membranes protrude beyond at least some of the threads, such that the hollow fiber membrane bundle has a smaller proportion of threads in a first and/or second end region, extending from the first and/or the second bundle end, than in a bundle region, located between the first and the second bundle end, which has a maximal proportion of threads, the length of the first end region and/or the length of the second end region being 1% to 45% of the bundle length.

A CMS membrane module includes plurality of hollow fiber CMS membranes that are enclosed within an open cylindrical shell whose ends are embedded in tubesheets. The shell is concentrically disposed within an open cylindrical pressure vessel whose open ends are covered by and secured by end caps. The shell includes a feed fluid inlet formed therein between the tubesheets and a retentate outlet in between one of the tubesheets and an adjacent end cap. A retentate seal is formed between the shell and the pressure vessel at a position between the tubesheets. A permeate seal is formed between the pressure vessel and the tubesheet that is adjacent a permeate port of the module. A structure made up of the CMS membranes, shell, tubesheets, and seals is slidable within the pressure vessel and not fixed in place in relation to the pressure vessel and end caps.

A membrane assembly includes a tube container having an inlet conduit and a first outlet conduit both oriented in a radial direction, and a second outlet conduit oriented in an axial direction; and a hollow fiber membrane element disposed inside the tube container, the hollow first membrane element comprising a first adapter with an axial permeate fluid passage in a center thereof and an inlet gas passage in a peripheral portion thereof; and a second adapter with an axial permeate fluid passage in a center thereof and a non-permeate fluid passage in a peripheral portion thereof.

In embodiments of the invention, there is provided a dialyzer or filter comprising hollow fibers, in which blood flows on the exterior of the hollow fibers, and dialysate or filtrate may flow on the inside. The external surfaces of the hollow fibers may have properties of smoothness and hemocompatibility. The fiber bundle may have appropriate packing fraction and may have wavy fibers. Optimum shear rates and blood velocities are identified. Geometric features of the cartridge, such as pertaining to flow distribution of the blood, may be different for different ends of the cartridge. Air bleed and emboli traps may be provided. Lengthened service life may be achieved by combinations of these features, which may permit additional therapies and applications or better economics.

A hollow fiber membrane module (100) of the present invention includes: a plurality of hollow fiber membranes (10); a binding portion (20) binding the plurality of hollow fiber membranes (10) at one end portions thereof; and a cap (30) having an internal space (30s) that communicates with each of the plurality of hollow fiber membranes (10), the cap (30) being integrated with the binding portion (20); and a housing (40) that houses the plurality of hollow fiber membranes (10) and the binding portion (20), and that has one end portion to which the cap (30) is attached. A unit (70) including the plurality of hollow fiber membranes (10), the binding portion (20), and the cap (30) is detached from the housing (40) and the unit (70) is attached to the housing (40) while integration of the binding portion (20) and the cap (30) is maintained.

Described herein is a method of using hollow fiber filter cartridge. The method includes: providing a hollow fiber filter cartridge inside or outside an environmental cleaning equipment; allowing a wastewater to enter the hollow fiber filter cartridge from an outside of the hollow fiber filter under no water pressure or low water pressure (such as under 30 gw/cm.sup.2); allowing the wastewater to cross a plurality of nanopores of the hollow fiber filter cartridge under no water pressure or low water pressure (such as under 30 gw/cm.sup.2) to produce a clean water; and allowing the environmental cleaning equipment to filter wastewater to produce clean water continuously, thereby improving cleaning efficiency and reducing water consumption.

A water treatment device using a hollow fiber membrane module is provided, including: a water container filled with raw water; a hollow fiber membrane module installed in the water container and provided with hollow fiber membranes therein to perform water treatment by a water pressure difference; and a raw water supplying part positioned on the water container, and configured to supply the raw water into the water container through the hollow fiber membrane module, in which the hollow fiber membrane module causes the raw water supplied from the raw water supplying part collide with the hollow fiber membrane to move the hollow fiber membrane, so that it is possible to minimize contamination of the hollow fiber membrane, minimize use of energy using electricity, and wash the hollow fiber membrane by a physical method.