Apparatus and methods for mixing and dispersing a dispersed phase in a medium comprise a rotating surface for receiving the medium and an atomizing apparatus positioned at the rotating surface for depositing aerosolized constituents of the dispersed phase into the medium. The medium is made receptive and the dispersed phase is aerosolized. Constituents of the aerosolized dispersed phase are deposited into the receptive medium to form a compound or composite. The medium may be deposited onto a rotating disk, and the dispersed phase may be sprayed onto the disk. A thin film can be generated on the disk to transfer, distribute, and disperse the dispersed phase. Liquid ligaments formed at the edge of the rotating disk further transfer, distribute, and disperse the dispersed phase into the medium. Ligaments may be broken into aerosols or deformed by attenuation/drawing to further promote transfer, distribution, and dispersion. A bulk composite/compound may be collected.

[Problem] To provide a device for manufacturing composite particles constructed by flow paths having relatively great widths and capable of controlling an adsorption ratio of particles, and to provide a method for manufacturing composite particles using this manufacturing device.

[Solution] A device for manufacturing composite particles includes at least one first inlet flow path (2) for supplying a first fluid, at least one second inlet flow path (3) for supplying a second fluid, and a mixing flow path (5) for merging the first fluid and the second fluid supplied respectively from the first inlet flow path and the second inlet flow path and allowing the two kinds of fluids to flow down for a predetermined length while mixing the two kinds of fluids. The mixing flow path is a continuous flow path and has a heterogeneous cross-sectional flow path area in a continuity direction thereof.

The method of obtaining stable suspensions of heterocrystals of titanium dioxide and particles of silicon dioxide representing special class of quantum dots (QD). and stable suspensions obtained in such a way for initiation of active form of oxygen in the human body in use in medical forms. Starting material: Initial stuff in the form of aggregates with size more than 0.5 micrometer is mixed with an aqueous solution of pharmaceutical inorganic acid, with subsequent direction to homogenizing for the first stage of mixing, after that the obtained aqueous suspension is subjected to thermal treatment and, then aqueous suspension is directed to the rotary rotor-type evaporator periodically for evaporation of inorganic acid with suspension expense trough the rotor-type evaporator no more than 25 l/min and then the obtained activated particles are mixed with water in hydrodynamical cavitation-wave cavitational homogenizer to quasi-with regulated pulsating wave mode until obtaining stable suspension of heterocrystal of titanium dioxide or particles of silicon dioxide with size less than 450 nm, and presence on the lattice surface up to 60-80% of electronically-excited triplet oxygen .sup.3+TO.sub.23O2 in the energy centers, namely, in the quantum dotszones of local overheating, ensuring heat synthesis catalytic activity for formation of active forms of oxygen in the living organism human body.

The surface of Stable suspension obtained by said method is characterized by distribution of activated crystals of titanium dioxide or with size up to 1 nm being 0.3 vol %, up to 20 nm being 5-40 vol %, particles with size up to 80 nm being 10-80 vol %, particles with size up to 150 nm being 5-30 vol %, particles with size up to 250 nm being 5-20 vol %, particles with size more than 250 nm-no more than 10 vol %, and distribution of activated particles of silicon dioxide with size 40-80 nm being 10-80 vol %, particles with size 80-150 nm being 10-80 vol %, particles with size 150-250 nm being less than 30 vol %, particles with size more than 250 nmno more than 15%. The surface of heterocrystals of titanium dioxide and particles of silicon dioxide has sorption ability, that is an important factor for use in medical forms, ensuring detoxication of an organism, elimination of hypoxia, antiviral effect of a medical agent, antipathogenous effect in the body of living organism and elimination of under oxidation processes in the human body, increasing induction of immune response of vertebrata.

A thermal insulation layer of the present disclosure includes a binder resin. The binder resin contains a plurality of aggregates. The aggregate has a plurality of primary inorganic nanoparticles with hydrophobic functional groups on their surfaces and at least one pore formed by being surrounded by these primary inorganic nanoparticles. A coating liquid for forming the thermal insulation layer of the present disclosure includes the plurality of aggregates and a plurality of binder resin particles in solvent. The solvent contains water and alcohol. A ratio of the alcohol to the entire solvent is less than 46% by volume. In a method of manufacturing the thermal insulation layer of the present disclosure, the coating liquid is coated in a layered manner on a substrate, and then, the coated layer is dried to form the thermal insulation layer.