A reactor system includes a reactor vessel configured to contain a process fluid, and a sparger assembly that operably coupled to the reactor vessel and configured to supply a mixture of a gas and a recirculated process fluid to the reactor vessel. The sparger assembly includes a plurality of sparger chambers. Each sparger chamber includes a process fluid conduit fluidly coupled to a process fluid return of the reactor vessel via a process fluid inlet, wherein the process fluid inlet has a first block and bleed valve assembly. Each sparger chamber includes a sparger conduit fluidly coupled to the process fluid conduit and a sparger disposed within the sparger conduit and fluidly coupled to a gas source via a gas inlet. Each sparger chamber also includes a process fluid-gas mixture outlet that fluidly couples the sparger conduit to a sparger outlet of the reactor vessel.

Systems and methods are described for supplying a rinsing liquid including ultrapure water and an ammonia gas. The system includes an ultrapure water source and a gas mixture source in fluid communication with a contactor. The gas mixture includes ammonia gas and a carrier gas. The system includes a control unit configured to adjust a flow rate of the ultrapure water source such that an operational pressure of the contactor remains below a pressure threshold. The system includes a compressor configured to remove a residual transfer gas out of the contactor. The contactor generates a rinsing liquid having ultrapure water and a concentration of the ammonia gas dissolved therein. The system includes a pump in fluid communication between the contactor and an outlet. The pump is configured to deliver the rinsing liquid having a gaseous partial pressure below the pressure threshold at the outlet.

The present disclosure relates to an extrusion apparatus comprising: a) a planetary roller extruder; b) a melt pump arranged downstream of the extruder; c) optionally, a fluid feeding equipment; d) a static cooling mixer equipment arranged downstream of the melt pump; e) a foaming equipment arranged downstream of the static cooling mixer equipment. The present disclosure also relates to a process of manufacturing a foamed polymeric composition and uses thereof.

Emulsifier particles and methods for making and using same. The emulsifier particles can include an alkali metal salt or an alkaline earth metal salt of a carboxylic acid terminated fatty amine condensate, an alkali metal salt or an alkaline earth metal salt of a modified tall oil, or a blend of an alkali metal salt or an alkaline earth metal salt of a carboxylic acid terminated fatty amine condensate and an alkali metal salt or an alkaline earth metal salt of a modified tall oil. The emulsifier particles can have a BET specific surface area of about 0.3 m.sup.2/g to about 1 m.sup.2/g. The method for making the emulsifier particles can include reducing a size of an emulsifier solid via a mechanical attrition process to produce the emulsifier particles.

Provided are a method for preparing liposomes comprising ultrasound reactive microbubbles for drug delivery, comprising (a) a step of producing ultrasound reactive microbubbles comprising an inert gas therein and having a first shell formed on the outer surface thereof, followed by forming a uniform size distribution of the ultrasound reactive microbubbles through an extruder; and (b) a step of producing liposomes comprising the ultrasound reactive microbubbles distributed in a uniform size and a medicament therein and having a second shell formed on the outer surface thereof, followed by forming a uniform size distribution of the liposomes through an extruder; and a liposome using same.

The present invention is a liquid material vaporizing device that heats a liquid material supplying pipe without providing a heating mechanism, the liquid material vaporizing device including: a gas-liquid mixer unit configured to mix a liquid material and a gas to generate a gas-liquid mixture; a liquid material supplying pipe configured to supply the liquid material to the gas-liquid mixer unit; a vaporizer unit configured to heat the gas-liquid mixture to vaporize the liquid material; and a casing configured to house the gas-liquid mixer unit, the vaporizer unit, and the liquid material supplying pipe, in which a channel configured to guide convection of heat from the vaporizer unit to the liquid material supplying pipe is provided inside the casing.

Provided herein is a method for preparing microcarrier particles, comprising the steps of allowing the dispersed phase liquid flow through a multi-hole plate at a low temperature to form liquid microspheres in a continuous phase, and enabling a synthetic polymer and/or natural biological macromolecules within the liquid microspheres to be subject to a curing reaction at a low temperature to form particles. Further provided herein are the method for preparing an emulsion and an apparatus and process system for preparing microcarrier particles, which can be used for preparing emulsions and microcarrier particles on a large scale.

Provided is a slurry treatment apparatus includes: a treatment tank for performing any treatment of a solid-liquid reaction, a solid-gas reaction, a gas-liquid reaction, and solid-liquid separation on a slurry containing a metal or a metal compound; a first pipe; a second pipe; and a pump, in which one end of the first pipe has a suction opening for sucking the slurry from the treatment tank, the other end of the first pipe is connected to a suction port of the pump, one end of the second pipe is linked to a discharge port of the pump, the other end of the second pipe is connected to a microbubble generator, and the microbubble generator includes a throttle that throttles a flow of the slurry and a gas supply tube for supplying gas to the throttle, and supplies microbubbles to the slurry in the treatment tank.

Provided is a slurry treatment apparatus includes: a treatment tank for performing any treatment of a solid-liquid reaction, a solid-gas reaction, a gas-liquid reaction, and solid-liquid separation on a slurry containing a metal or a metal compound; a first pipe; a second pipe; and a pump, in which one end of the first pipe has a suction opening for sucking the slurry from the treatment tank, the other end of the first pipe is connected to a suction port of the pump, one end of the second pipe is linked to a discharge port of the pump, the other end of the second pipe is connected to a microbubble generator, and the microbubble generator includes a throttle that throttles a flow of the slurry and a gas supply tube for supplying gas to the throttle, and supplies microbubbles to the slurry in the treatment tank.

An ultra-fine bubble-containing liquid generating apparatus (UFB-containing liquid generating apparatus) includes a dissolving unit that generates a gas dissolving liquid and an ultra-fine bubble generating unit that generates ultra-fine bubbles in the gas dissolving liquid. Additionally, the UFB-containing liquid generating apparatus includes a temperature controlling unit that controls at least one of temperatures of the dissolving unit and the ultra-fine bubble generating unit such that the temperature of the ultra-fine bubble generating unit is equal to or lower than the temperature of the dissolving unit.