A device (30) includes a base connector (32) having an opening (33) and an impeller connector (64) coupled to the base connector (32). The impeller connector (64) has a through-passage (66) aligned with the opening (33) of the base connector (32). Further, the device (30) includes a flexible tube (34) having a first end (36) and a second end (40), where the first end (36) of the flexible tube (34) is coupled to the impeller connector (64). Furthermore, the device (30) includes a seal component (38) and an impeller (42) coupled to the second end (40) of the flexible tube (34). Additionally, the device (34) includes an enclosure (46) disposed enclosing the impeller (42), the flexible tube (34), the impeller connector (64), and the base connector (32).

A device (30) includes a base connector (32) having an opening (33) and an impeller connector (64) coupled to the base connector (32). The impeller connector (64) has a through-passage (66) aligned with the opening (33) of the base connector (32). Further, the device (30) includes a flexible tube (34) having a first end (36) and a second end (40), where the first end (36) of the flexible tube (34) is coupled to the impeller connector (64). Furthermore, the device (30) includes a seal component (38) and an impeller (42) coupled to the second end (40) of the flexible tube (34). Additionally, the device (34) includes an enclosure (46) disposed enclosing the impeller (42), the flexible tube (34), the impeller connector (64), and the base connector (32).

An impeller assembly for a solid-liquid mixing device, which includes an impeller body, multiple mixing blades which are evenly distributed on the inner side of the impeller body and extended outwards from the shaft of the impeller body, and at least two baffle plates being disposed on the outer side of the impeller body along a radial direction thereof outwards and disposed in the circumferential direction of the impeller body. At least one pair of adjacent two baffle plates satisfies following conditions: curves projected by two opposite surfaces of each of adjacent baffle plates on a cross section of the impeller at any height are smooth curves, and at least one of the curves is not fully included in a circle with the center of the shaft as its center.

An impeller assembly for a solid-liquid mixing device, which includes an impeller body, multiple mixing blades which are evenly distributed on the inner side of the impeller body and extended outwards from the shaft of the impeller body, and at least two baffle plates being disposed on the outer side of the impeller body along a radial direction thereof outwards and disposed in the circumferential direction of the impeller body. At least one pair of adjacent two baffle plates satisfies following conditions: curves projected by two opposite surfaces of each of adjacent baffle plates on a cross section of the impeller at any height are smooth curves, and at least one of the curves is not fully included in a circle with the center of the shaft as its center.

Disclosed is direct ink write (DIW) print extrusion head for 3D printing of viscous elastomers. The disclosed print extrusion head comprises a mixer assembly, comprising a fluid distribution cap coupled to a carrier, an in-line mixer coupled to the fluid distribution cap. A cooling jacket surrounds the in-line mixer. A nozzle is coupled to the in-line mixer and protrudes below the cooling jacket over a work surface. The position of the nozzle relative to the work surface is changeable. At least one heat source is on the chassis and disposed adjacent to the fluid distribution cap. The at least one heat source comprises a heat guiding element to direct heat to a region onto the work surface below the nozzle.

Disclosed is direct ink write (DIW) print extrusion head for 3D printing of viscous elastomers. The disclosed print extrusion head comprises a mixer assembly, comprising a fluid distribution cap coupled to a carrier, an in-line mixer coupled to the fluid distribution cap. A cooling jacket surrounds the in-line mixer. A nozzle is coupled to the in-line mixer and protrudes below the cooling jacket over a work surface. The position of the nozzle relative to the work surface is changeable. At least one heat source is on the chassis and disposed adjacent to the fluid distribution cap. The at least one heat source comprises a heat guiding element to direct heat to a region onto the work surface below the nozzle.

A single-use bioreactor is provided. The single-use bioreactor may include a bioprocess container, a shell, at least one agitator, at least one sparger, at least one gas filter inlet port for the sparger(s) and headspace overlay, at least one fill port, at least one harvest port, at least one sample port, and at least one probe. In examples, at least one controller may monitor and control one or more parameters associated with the single-use bioreactor A method to cultivate and propagate mammalian cells is also provided. The method may include cultivating under suitable conditions and in a suitable culture medium in a first single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a second single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a third single-use bioreactor, and cultivating the cells in the third bioreactor.

A chemical mixer tool for use in a storage drum is described. The chemical mixer tool typically comprises a mixer housing assembly in which one end of a mixer shaft is secured, the distal end of the mixer shaft having at least one collapsible impeller assembly removably attached thereon. The chemical mixer tool is configured to be removably secured to the top portion of the storage drum, with the distal end of the mixing shaft extending into the interior of the storage drum.

A chemical mixer tool for use in a storage drum is described. The chemical mixer tool typically comprises a mixer housing assembly in which one end of a mixer shaft is secured, the distal end of the mixer shaft having at least one collapsible impeller assembly removably attached thereon. The chemical mixer tool is configured to be removably secured to the top portion of the storage drum, with the distal end of the mixing shaft extending into the interior of the storage drum.

A single stage clarifier and mixing assembly includes a housing, a mixing section within the housing and a clarifier section within the housing. The mixing section includes a mixing chamber having (a) an inlet, adapted for delivering an inlet stream to the mixing chamber, at an upper end, and (b) a mixing section outlet at a lower end. The clarifier section extends concentrically around the mixing section. The single stage clarifier and mixing assembly also includes an agitator adapted for mixing the inlet stream in the mixing chamber.