The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.

The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.

A system for separating solids from a fluid mixture includes a vessel including a first chamber to receive a solid-laden fluid mixture, and a second chamber to receive liquids separated from the solid-laden fluid mixture. In certain aspects, at least one eductor is disposed in the first chamber to flow the solid-laden fluid mixture out of the first chamber. In certain aspects, an auger is disposed in the first chamber to move at least solids of the solid-laden fluid mixture out of the first chamber.

The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.

The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.

The unique shape of the helical beater described herein not only achieves higher mixing performance but also power efficiency. By using high strength plastics instead of metal, the improved helical beater design described herein will lower or fix material and manufacturing costs and will provide a better method of controlling the geometry of the beater body.

A device, which serves to separate particles of a bulk material, which is deliverable at an input location and is removable processed in different or at least approximately unitary particle sizes at an output location, includes at least one separating element, which has a metal separating plate with through-openings provided therein, which separating element can be provided with ultrasonic energy and for this purpose is connected to an ultrasonic transducer and which is held by a holding device. The holding device is a mounting shaft, which is held at one end or at both ends fixedly or movably, in particular rotatably and/or axially displaceable, and which at one end or at both ends is connected to an ultrasonic transducer, by means of which ultrasonic energy is couplable via the mounting shaft into the separating element, which is designed to be dimensionally stable.

Disclosed is a washing machine with an improved stirring device. The washing machine includes a tub, a rotating tub rotatably provided in the tub, a stirring device including a first stirring portion rotatably provided below the rotating tub, and a second stirring portion coupled to the first stirring portion. The second stirring portion includes a cylindrical wash rod body and a groove that is recessed from an outer surface of the wash rod body and extends in a longitudinal direction to accommodate a parting line formed by a manufacturing process.

Disclosed is a washing machine with an improved stirring device. The washing machine includes a tub, a rotating tub rotatably provided in the tub, a stirring device including a first stirring portion rotatably provided below the rotating tub, and a second stirring portion coupled to the first stirring portion. The second stirring portion includes a cylindrical wash rod body and a groove that is recessed from an outer surface of the wash rod body and extends in a longitudinal direction to accommodate a parting line formed by a manufacturing process.

A device, which serves to separate particles of a bulk material, which is deliverable at an input location and is removable processed in different or at least approximately unitary particle sizes at an output location, includes at least one separating element, which has a metal separating plate with through-openings provided therein, which separating element can be provided with ultrasonic energy and for this purpose is connected to an ultrasonic transducer and which is held by a holding device. The holding device is a mounting shaft, which is held at one end or at both ends fixedly or movably, in particular rotatably and/or axially displaceable, and which at one end or at both ends is connected to an ultrasonic transducer, by means of which ultrasonic energy is couplable via the mounting shaft into the separating element, which is designed to be dimensionally stable.