A single-screw extruder for conveying and plasticizing a meltable material, including a screw and a heated cylinder, wherein the screw is rotatably held in the heated cylinder, the screw has a core and a helical main flight, which is at a first distance from the internal wall of the cylinder, a region of a transition zone and a melting zone has at least two successive, non-overlapping barrier portions, and a cylinder-side outside flight surface of one or more overflow flights is chamfered in full or in part over a flight width such that a conical gap that gets narrower in an overflow direction is formed between the internal wall of the cylinder and the cylinder-side outside flight surface.

A single-screw extruder for conveying and plasticizing a meltable material, including a screw and a heated cylinder, wherein the screw is rotatably held in the heated cylinder, the screw has a core and a helical main flight, which is at a first distance from the internal wall of the cylinder, a region of a transition zone and a melting zone has at least two successive, non-overlapping barrier portions, and a cylinder-side outside flight surface of one or more overflow flights is chamfered in full or in part over a flight width such that a conical gap that gets narrower in an overflow direction is formed between the internal wall of the cylinder and the cylinder-side outside flight surface.

A dosing machine for dosing fluid products includes: containers having vertical longitudinal axes and configured to contain fluid products, rotary stirring elements located inside respective containers and operable in rotation by electric motors, and a dispensing head having nozzles connected to respective containers, where each container is associated with a level measuring device having: a floater containing a permanent magnet and free to move inside the container, a magnetic detector arranged outside the container, and having magnetic sensors spaced apart from each other in a vertical direction and each of which is configured to detect a variation in a magnetic field caused by passage in its proximity of said floater, and a control unit which analyzes signals provided by the magnetic sensors to detect a fluid level inside the container and passage of the floater in a vicinity of one or more of said magnetic sensors.

A single-use bioreactor is provided. The single-use bioreactor may include a bioprocess container, a shell, at least one agitator, at least one sparger, at least one gas filter inlet port for the sparger(s) and headspace overlay, at least one fill port, at least one harvest port, at least one sample port, and at least one probe. In examples, at least one controller may monitor and control one or more parameters associated with the single-use bioreactor A method to cultivate and propagate mammalian cells is also provided. The method may include cultivating under suitable conditions and in a suitable culture medium in a first single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a second single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a third single-use bioreactor, and cultivating the cells in the third bioreactor.

A stirrer includes a shaft, and a plurality of stirring blades mounted on the shaft along a longitudinal direction of the shaft. The stirrer is configured to stir molten glass in a stirring vessel by causing the plurality of stirring blades to turn about the shaft in association with rotation of the shaft. The plurality of stirring blades (blade bodies) each have a through opening and a distal end portion extending along the longitudinal direction of the shaft. The plurality of stirring blades are mounted on the shaft so that, when the plurality of stirring blades turn about the shaft, the stirring blades that are closer to one end side of the shaft are delayed in phase around the shaft with respect to the stirring blades on another end side of the shaft.

A stirrer includes a shaft, and a plurality of stirring blades mounted on the shaft along a longitudinal direction of the shaft. The stirrer is configured to stir molten glass in a stirring vessel by causing the plurality of stirring blades to turn about the shaft in association with rotation of the shaft. The plurality of stirring blades (blade bodies) each have a through opening and a distal end portion extending along the longitudinal direction of the shaft. The plurality of stirring blades are mounted on the shaft so that, when the plurality of stirring blades turn about the shaft, the stirring blades that are closer to one end side of the shaft are delayed in phase around the shaft with respect to the stirring blades on another end side of the shaft.

The present invention relates to a bio-reaction stirrer using a magnetic force. According to an embodiment of the present invention, a driving coupling part is axially formed inside a housing part and a plurality of impellers are provided according to the height direction of the driving coupling part, and the respective impellers can be selectively driven as necessary, thereby efficiently stirring the entire inside of the housing part.

The changes to the abstract are shown below:

The present invention relates to a bio-reaction stirrer using a magnetic force. According to an embodiment of the present invention, a driving coupling part is axially formed inside a housing part and a plurality of impellers are provided according to the height direction of the driving coupling part, and the respective impellers can be selectively driven as necessary, thereby efficiently stirring the entire inside of the housing part.

The present invention provides for precision stirrers and mixers which are precision devices for the control of mixing and stirring in liquid and non-liquid systems. As will become obvious, the devices provided for in the present invention may be used for mixing or stirring by adjusting the device configurations and allow precise desired ingredient addition.

An impeller, for example, a Rushton impeller for a bioreactor system is disclosed. The impeller includes a hub, optionaly including a slot, a plurality of blades, and one or more turbulators. The plurality of blades is disposed along a circumferential direction of the hub and spaced apart from each other. Each of the plurality of blades is coupled to at least a portion of a circumference and/or a top surface of the hub. Each blade of the plurality of blades includes a pressure face and a suction face. The one or more turbulators is disposed on at least a portion of the suction face, the pressure face, or both, of a blade of the plurality of blades.

An impeller, for example, a Rushton impeller for a bioreactor system is disclosed. The impeller includes a hub, optionaly including a slot, a plurality of blades, and one or more turbulators. The plurality of blades is disposed along a circumferential direction of the hub and spaced apart from each other. Each of the plurality of blades is coupled to at least a portion of a circumference and/or a top surface of the hub. Each blade of the plurality of blades includes a pressure face and a suction face. The one or more turbulators is disposed on at least a portion of the suction face, the pressure face, or both, of a blade of the plurality of blades.