A stirrer is provided that can more efficiently achieve shearing applied, by an action of an intermittent jet flow, to a fluid to be processed. The stirrer concentrically includes a rotor including a blade, a partition wall, and a screen, wherein: the screen includes a plurality of slits in a circumferential direction thereof and screen members located between the adjacent slit; by rotating at least the rotor of the two components, the fluid to be processed is discharged from the inside to the outside of the screen as the intermittent jet flow through the slit of the screen; the screen has a cylindrical shape having a circular cross section; an opening of the slit provided on the inner wall surface of the screen is used as an inflow opening; openings of the plurality of slits provided on the outer wall surface of the screen are used as outflow openings; and the width of the outflow openings in the circumferential direction is set to be smaller than the width of the inflow opening in the circumferential direction.

A vacuum deaerator degasses material to be processed by placing a rotating rotor with a screen in a vacuum vessel, introducing a liquid material to be processed into the rotor from the interior thereof and causing the liquid to pass through the screen to refine the same. The vacuum deaerator is characterized in that: the screen is a cylinder with a circular cross-section and is in the form of a porous plate in which a plurality of through holes are opened in the radial direction of the cylindrical screen; and the screen is provided such that the area of inflow openings is greater than the area of outflow openings, where the inflow openings are openings of a plurality of penetration portions provided on the inner wall face of the screen and the outflow openings are openings of the plurality of penetration portions provided on the outer wall dace of the screen. Thus, the processing capacity of the vacuum deaerator is improved without increasing the size of the device.

A stirrer is provided that can more efficiently achieve shearing applied, by an action of an intermittent jet flow, to a fluid to be processed. The stirrer concentrically includes a rotor including a blade, a partition wall, and a screen, wherein: the screen includes a plurality of slits in a circumferential direction thereof and screen members located between the adjacent slit; by rotating at least the rotor of the two components, the fluid to be processed is discharged from the inside to the outside of the screen as the intermittent jet flow through the slit of the screen; the screen has a cylindrical shape having a circular cross section; an opening of the slit provided on the inner wall surface of the screen is used as an inflow opening; openings of the plurality of slits provided on the outer wall surface of the screen are used as outflow openings; and the width of the outflow openings in the circumferential direction is set to be smaller than the width of the inflow opening in the circumferential direction.

Disclosed is a fine bubble water generator including: a housing being configured with an inflow line on one end thereof where air and fluid enters and a discharge line on an opposite end where fine bubble water is discharged; a partition allowing the air and fluid entered into the inflow line to flow in zigzags inside the housing; and a fine bubble water generation cylinder unit, being inserted into a space formed by the partition, allowing the air and fluid to be induced to collide with a surface thereof having bumps formed thereon and on an inner circumferential surface of the housing or the partition, thereby refining air bubbles and fluid by frictional force caused by a flat surface and the partition.

Disclosed is a fine bubble water generator including: a housing being configured with an inflow line on one end thereof where air and fluid enters and a discharge line on an opposite end where fine bubble water is discharged; a partition allowing the air and fluid entered into the inflow line to flow in zigzags inside the housing; and a fine bubble water generation cylinder unit, being inserted into a space formed by the partition, allowing the air and fluid to be induced to collide with a surface thereof having bumps formed thereon and on an inner circumferential surface of the housing or the partition, thereby refining air bubbles and fluid by frictional force caused by a flat surface and the partition.

A stirring-processing apparatus and a processing method are provided to realize excellent processing of a fluid regardless of the properties of the fluid. The stirring-processing apparatus is provided with the stirring blade and the stirring chamber provided with the screen, wherein the apparatus performs, under a state in which the stirring chamber is disposed in a fluid to be processed, a process of applying a shear force to the fluid by a relative rotation between the screen and the stirring blade. The stirring chamber is provided with the suction opening to suck the fluid from outside to inside and the ejecting opening to eject the fluid from inside to outside; these openings being disposed above and below. The suppressing body to control a flow of the fluid is disposed between the suction opening and the ejecting opening. The suppressing body is, for example, in the form of a cylinder, and is interposed between the suction flow and the ejecting flow, thereby suppressing interference between the two flows.

The present invention relates to a solid dispersion characterized in that it comprises carbamic acid 3-(4-benzyloxy-phenyl)-isoxazol-5-ylmethyl ester as an active ingredient and a water-soluble polymer having a glass transition temperature lower than the melting point of the active ingredient as a carrier, and it is prepared via melt extrusion. The solid dispersion of the present invention remarkably increases the solubility and dissolution rate of the active ingredient which is an insoluble drug to efficiently improve the bioavailability when it is orally administered.

The present invention relates to a solid dispersion characterized in that it comprises carbamic acid 3-(4-benzyloxy-phenyl)-isoxazol-5-ylmethyl ester as an active ingredient and a water-soluble polymer having a glass transition temperature lower than the melting point of the active ingredient as a carrier, and it is prepared via melt extrusion. The solid dispersion of the present invention remarkably increases the solubility and dissolution rate of the active ingredient which is an insoluble drug to efficiently improve the bioavailability when it is orally administered.

The present invention relates to a solid dispersion characterized in that it comprises carbamic acid 3-(4-benzyloxy-phenyl)-isoxazol-5-ylmethyl ester as an active ingredient and a water-soluble polymer having a glass transition temperature lower than the melting point of the active ingredient as a carrier, and it is prepared via melt extrusion. The solid dispersion of the present invention remarkably increases the solubility and dissolution rate of the active ingredient which is an insoluble drug to efficiently improve the bioavailability when it is orally administered.